Disruptive anti-IgE inhibitors prevent mast cell-dependent early airway response in viable atopic lung tissue

Autor: Delgado, S.J., Dehmel, S., Twisterling, E., Wichmann, J., Jonigk, D., Warnecke, G., Braubach, P., Fieguth, H.-G., Wilkens, L., Dahlmann, F., Kaup, F.-J., Eggel, A., Knauf, S., Sewald, K., Braun, A.

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Disruptive anti-IgE inhibitors prevent mast cell-dependent early airway response in viable atopic lung tissue.

Autor: Delgado SJ; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany., Dehmel S; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany., Twisterling E; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany; German Primate Center GmbH, Leibniz-Institute for Primate Research, Goettingen, Germany., Wichmann J; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany; German Primate Center GmbH, Leibniz-Institute for Primate Research, Goettingen, Germany., Jonigk D; Institute for Pathology, Hannover Medical School, Hannover, Germany, Member of the German Center for Lung Research (DZL), Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Research Network, Hannover, Germany., Warnecke G; Institute for Pathology, Hannover Medical School, Hannover, Germany, Member of the German Center for Lung Research (DZL), Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Research Network, Hannover, Germany., Braubach P; Institute for Pathology, Hannover Medical School, Hannover, Germany, Member of the German Center for Lung Research (DZL), Hannover, Germany, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH) Research Network, Hannover, Germany., Fieguth HG; Institute of Pathology, Klinikum Region Hannover (KRH), Hannover, Germany., Wilkens L; Institute of Pathology, Klinikum Region Hannover (KRH), Hannover, Germany., Dahlmann F; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany., Kaup FJ; German Primate Center GmbH, Leibniz-Institute for Primate Research, Goettingen, Germany., Eggel A; Department of Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland., Knauf S; German Primate Center GmbH, Leibniz-Institute for Primate Research, Goettingen, Germany., Sewald K; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany. Electronic address: katherina.sewald@item.fraunhofer.de., Braun A; Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Center for Lung Research (DZL), Biomedical Research in Endstage and Obstructive Lung Disease (BREATH) research network, Hannover, Germany.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2020 Feb; Vol. 145 (2), pp. 719-722.e1. Date of Electronic Publication: 2019 Dec 16.