Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Twishi Gulati"'
Autor:
Susanne Ramm, Robert Vary, Twishi Gulati, Jennii Luu, Karla J. Cowley, Michael S. Janes, Nicholas Radio, Kaylene J. Simpson
Publikováno v:
Organoids, Vol 2, Iss 1, Pp 1-19 (2022)
Technical advances in microscopy and automation have enabled image-based phenotypic screening of spheroids and organoids to become increasingly high throughput and high content at the same time. In particular, matrix-embedded 3D structures can recapi
Externí odkaz:
https://doaj.org/article/9872d9af8f674af8a0a211c1ce1aa687
Autor:
Cristina Gamell, Ivona Bandilovska, Twishi Gulati, Arielle Kogan, Syer Choon Lim, Zaklina Kovacevic, Elena A. Takano, Clelia Timpone, Arjelle D. Agupitan, Cassandra Litchfield, Giovanni Blandino, Lisa G. Horvath, Stephen B. Fox, Scott G. Williams, Andrea Russo, Enzo Gallo, Piotr J. Paul, Catherine Mitchell, Shahneen Sandhu, Simon P. Keam, Sue Haupt, Des R. Richardson, Ygal Haupt
Publikováno v:
iScience, Vol 22, Iss , Pp 1-15 (2019)
Summary: Although primary prostate cancer is largely curable, progression to metastatic disease is associated with very poor prognosis. E6AP is an E3 ubiquitin ligase and a transcriptional co-factor involved in normal prostate development. E6AP drive
Externí odkaz:
https://doaj.org/article/b647e01078dd499387cf60597e19c626
Autor:
Giovanni Blandino, Des R. Richardson, Arielle Kogan, Arjelle Decasa Agupitan, Andrea Russo, Ivona Bandilovska, Simon P. Keam, Piotr J. Paul, Syer Choon Lim, Scott Williams, Ygal Haupt, Cristina Gamell, Sue Haupt, Lisa G. Horvath, Cassandra Litchfield, Clelia Timpone, Stephen B. Fox, Enzo Gallo, Zaklina Kovacevic, Catherine Mitchell, Shahneen Sandhu, Twishi Gulati, Elena A Takano
Publikováno v:
iScience, Vol 22, Iss, Pp 1-15 (2019)
iScience
iScience
Summary Although primary prostate cancer is largely curable, progression to metastatic disease is associated with very poor prognosis. E6AP is an E3 ubiquitin ligase and a transcriptional co-factor involved in normal prostate development. E6AP drives
Autor:
Sue Haupt, Scott Williams, Simon P. Keam, Cheng Huang, Dinesh Raghu, Cristina Gamell, Piotr J. Paul, Robert J. A. Goode, Oded Kleifeld, Ralf B. Schittenhelm, Franco Caramia, Ygal Haupt, Twishi Gulati
Publikováno v:
Molecular & Cellular Proteomics. 17:1170-1183
Prostate cancer is a common cause of cancer-related death in men. E6AP (E6-Associated Protein), an E3 ubiquitin ligase and a transcription cofactor, is elevated in a subset of prostate cancer patients. Genetic manipulations of E6AP in prostate cancer
Autor:
Oded Kleifeld, Ralf B. Schittenhelm, Ygal Haupt, Paul J Neeson, Cheng Huang, Simon P. Keam, Cristina Gamell, Scott Williams, Franco Caramia, Twishi Gulati
Publikováno v:
The Prostate. 78:563-575
Introduction The development of radioresistance in prostate cancer (PCa) is an important clinical issue and is still largely uninformed by personalized molecular characteristics. The aim of this study was to establish a platform that describes the ea
Autor:
Giovanni Blandino, Dinesh Raghu, Scott Williams, Cristina Gamell, Siddhartha Deb, Ygal Haupt, Andrea Russo, Christine Khoo, Shahneen Sandhu, Stephen B. Fox, Ai-Leen Chan, Twishi Gulati, Enzo Gallo, Sue Haupt, Elena A Takano, Piotr J. Paul
Publikováno v:
Oncotarget
Prostate cancer (PC) is the most common cancer in men. Elevated levels of E3 ligase, E6-Associated Protein (E6AP) were previously linked to PC, consistent with increased protein expression in a subset of PC patients. In cancers, irregular E3 ligase a
Autor:
Osamu Ohara, Mathias Müller, Supreet Kaur, Matthew J. Watt, Catriona McLean, Tony Tiganis, Pei Pk Goh, S. D. Archer, Esteban Nicolas Gurzov, Geraldine Gj Ooi, Aliki A. Rasmiena, Wendy A. Brown, Florian Wiede, Marcus Grohmann, Garron Gt Dodd, Aislinn Ae Treloar, Tariq M. Butt, Twishi Gulati
Publikováno v:
Cell, 175 (5
Cell
Cell
Summary Obesity is a major driver of cancer, especially hepatocellular carcinoma (HCC). The prevailing view is that non-alcoholic steatohepatitis (NASH) and fibrosis or cirrhosis are required for HCC in obesity. Here, we report that NASH and fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2fcbf32bd702a49d00d75d13c4ba75
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/284063
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/284063
Autor:
Luke S. Lambeth, Robert L. Vessella, Mark Shackleton, Ai-Leen Chan, Dinesh Raghu, Eriko Takano, Scott Williams, Piotr J. Paul, Ygal Haupt, Elizabeth D. Williams, Stephen B. Fox, Cristina Gamell, Twishi Gulati, Clare G Fedele, Marco J Herold, Sue Haupt, Jim Hagekyriakou
Publikováno v:
Oncogene. 35:6235-6245
Restoration of tumor suppression is an attractive onco-therapeutic approach. It is particularly relevant when a tumor suppressor is excessively degraded by an overactive oncogenic E3 ligase. We previously discovered that the E6-associated protein (E6
Autor:
Oded Kleifeld, Ralf B. Schittenhelm, Cheng Huang, Franco Caramia, Gisela Mir Arnau, Cristina Gamell, Ygal Haupt, Paul J Neeson, Simon P. Keam, Twishi Gulati, Scott Williams
Publikováno v:
Radiation and environmental biophysics. 57(3)
Transcriptional dosimetry is an emergent field of radiobiology aimed at developing robust methods for detecting and quantifying absorbed doses using radiation-induced fluctuations in gene expression. A combination of RNA sequencing, array-based and q
Autor:
Bojiang Shen, Divya Bhargav, Sarennya Pathmanandavel, Twishi Gulati, Aiqun Wei, Ashish D. Diwan, Lisa A. Williams, Zhimin Fang
Publikováno v:
Journal of Orthopaedic Research. 34:279-289
During embryogenesis vertebral segmentation is initiated by sclerotomal cell migration and condensation around the notochord, forming anlagen of vertebral bodies and intervertebral discs. The factors that govern the segmentation are not clear. Previo