Keeping together: older people in longitudinal research studies, the case of TwinsUK

Autor: Mein, Gill, Bhatti, Taha, Bailey, Sarah, Steves, Claire J., Hart, Deborah, Garcia, Paz, Tinker, Anthea

Publikováno v: Working with Older People, 2020, Vol. 25, Issue 2, pp. 105-114.

Externí odkaz: http://www.emeraldinsight.com/doi/10.1108/WWOP-02-2020-0007

Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches

Autor: Marko Tijardović, Toma Keser, Gordan Lauc, Markus Perola, Tim D. Spector, Olga Gornik, Massimo Mangino, Domagoj Kifer, Cristina Menni, Mario Falchi, Ana Cvetko

Publikováno v: BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)

IntroductionPrediction of type 2 diabetes mellitus (T2DM) and its preceding factors, such as insulin resistance (IR), is of great importance as it may allow delay or prevention of onset of the disease. Plasma protein N-glycome has emerged as a promis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aea09848ecba2b5a91c6e9cc3c3c14b
https://pubmed.ncbi.nlm.nih.gov/34518155

Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs

Autor: Craig A. Glastonbury, Alexessander Couto Alves, Kerrin S. Small, Julia S. El-Sayed Moustafa

Publikováno v: American Journal of Human Genetics
Glastonbury, C A, Couto Alves, A, El-Sayed Moustafa, J S & Small, K S 2019, ' Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs ', American Journal of Human Genetics, vol. 104, no. 6, pp. 1013-1024 . https://doi.org/10.1016/j.ajhg.2019.03.025

Adipose tissue is an important endocrine organ with a role in many cardiometabolic diseases. It is comprised of a heterogeneous collection of cell types that can differentially impact disease phenotypes. Cellular heterogeneity can also confound -omic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7905f50dd7141e92bedf4e660f18b364
https://doi.org/10.1101/283929

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Prevalence and risk factors of dry eye disease in a British female cohort

Autor: Christopher J Hammond, Pirro G. Hysi, Jelle Vehof, Diana Kozareva

Publikováno v: BRITISH JOURNAL OF OPHTHALMOLOGY, 98(12), 1712-1717. BMJ PUBLISHING GROUP

To estimate the prevalence and risk factors of dry eye disease (DED) in a female cohort in the UK.Population-based cross-sectional association study of 3824 women from the TwinsUK cohort aged 20-87 years. A questionnaire was used to evaluate DED and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4d630c847cc4b8eb0820ee0759c0b5
https://doi.org/10.1136/bjophthalmol-2014-305201