Galactosylation of human IgG monoclonal anti-D produced by EBV-transformed B-lymphoblastoid cell lines is dependent on culture method and affects Fc receptor-mediated functional activity

Autor: Bm, Kumpel, Tw, Rademacher, Graham Rook, Pj, Williams, Ib, Wilson

Publikováno v: Europe PubMed Central

Human monoclonal antibodies to the Rh D blood group antigen were produced by EBV-transformed B cell lines grown in serum-free medium in low density (LD) static cultures or high density (HD) hollow fiber bioreactors. Glycosylation analysis of the puri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::18b071fb750a354774e45e9adba1d3b8
https://pubmed.ncbi.nlm.nih.gov/7756579

The isolation by ligand affinity chromatography of a novel form of alpha-L-fucosidase from almond

Autor: Scudder P, David Neville, Td, Butters, Gw, Fleet, Ra, Dwek, Tw, Rademacher, Gs, Jacob

Publikováno v: Europe PubMed Central

An alpha-fucosidase has been extracted from almond meal and purified 163,000-fold to apparent homogeneity using a novel affinity ligand, N-(5-carboxy-1-pentyl)-1,5-dideoxy-1,5-imino-L-fucitol, coupled to Affi-Gel 102. Substrate specificity studies de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::80ec32dcb229c25781b2c0a6e631a4ad
https://pubmed.ncbi.nlm.nih.gov/2398059

A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test.

Autor: Scioscia M; Department of Obstetrics and Gynaecology, Policlinico Hospital, Abano Terme, Padua 35031, Italy. Electronic address: marcoscioscia@gmail.com., Dekker GA; Robinson Research Institute and School of Medicine, University of Adelaide, Adelaide, SA, Australia., Chaouat G; Institut National de Santé et de Recherche Médicale, INSERM UMR-976, Saint-Louis Hospital, Research Center, Paris, France., Dawonauth L; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius., Dechend R; Experimental and Clinical Research Center, Max-Delbrück Center for Molecular Medicine and Charité Universitätsmedizin Berlin, Berlin, Germany., Goldman-Wohl D; Magda and Richard Hoffman Center for Human Placenta Research, Department of Obstetrics and Gynecology, Hebrew University Hadassah Medical Center, Jerusalem, Israel., Gumilar E; Department Obstetrics & Gynecology, DR Soetomo-UNAIR Hospital, Universitas Airlangga, Surabaya, Indonesia., Karumanchi SA; Departments of Medicine and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Nephrology Division, Departments of Medicine, Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Kell DB; School of Chemistry, The University of Manchester, Manchester, UK., Rademacher TW; Division of Infection and Immunity, University College London Medical School, London, UK; Middlesex University, London, UK., Robertson S; Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Saito S; Department of Obstetrics and Gynecology, University of Toyama, Toyama, Japan., Scherjon S; Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands., Staff AC; Division of Obstetrics and Gynaecology, Oslo University Hospital, Norway; Faculty of Medicine, University of Oslo, Norway., Vatish M; Nuffield Department of Women's & Reproductive Health, University of Oxford, Women's Centre, John Radcliffe Hospital, Oxford, UK., Robillard PY; Service de Réanimation néonatale, Centre d'Etudes Périnatales Océan Indien, Centre Hospitalier Universitaire Sud-Réunion, Saint-Pierre, France.

Publikováno v: The Lancet. Global health [Lancet Glob Health] 2019 Oct; Vol. 7 (10), pp. e1312-e1313.

New insights into early and late onset subgroups of preeclampsia from longitudinal versus cross-sectional analysis of urinary inositol-phosphoglycan P-Type.

Autor: L'Omelette AD; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address: domiioshugoki@gmail.com., Dawonauth L; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius., Rademacher L; Sylus Pharmaceuticals Ltd., Abingdon, Oxford, United Kingdom., Robillard PY; Service de Néonatologie, Centre Hospitalier Universitaire Sud Réunion, La Réunion, Saint Pierre, France., Scioscia M; Department of Obstetrics and Gynecology, Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy., Jankee S; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius., Lee Kwai Yan MY; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius., Razgia JB; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius., Rademacher TW; Division of Infection and Immunity, University College London Medical School, London, United Kingdom; Middlesex University, London, United Kingdom.

Publikováno v: Journal of reproductive immunology [J Reprod Immunol] 2018 Feb; Vol. 125, pp. 64-71. Date of Electronic Publication: 2017 Dec 06.

Urinary inositol phosphoglycan-P type: near patient test to detect preeclampsia prior to clinical onset of the disease. A study on 416 pregnant Mauritian women.

Autor: Dawonauth L; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address: poonythl@uom.ac.mu., Rademacher L; Sylus Pharmaceuticals Ltd, Centre for Innovation and Enterprise, University of Oxford, Begbroke Science Park, Sandy Lane, Yarnton OX5 1PF, United Kingdom. Electronic address: laurensrademacher@syluspharma.com., L'Omelette AD; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address: domiioshugoki@gmail.com., Jankee S; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address: jankees@uom.ac.mu., Lee Kwai Yan MY; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address: leekwaiy@uom.ac.mu., Jeeawoody RB; Department of Medicine, Faculty of Science, University of Mauritius, Réduit, Mauritius. Electronic address: adil.jeeawoody@gmail.com., Rademacher TW; Research Department of Immunology, Division of Infection and Immunity, University College London Medical School, Windeyer Building, 46 Cleveland Street, London W1P 6DB, United Kingdom. Electronic address: t.rademacher@ucl.ac.uk.

Publikováno v: Journal of reproductive immunology [J Reprod Immunol] 2014 Mar; Vol. 101-102, pp. 148-152. Date of Electronic Publication: 2013 Aug 02.