NHEJ-dependent recruitment of PR-Set7 to DNA double strand breaks facilitates H4K20 methylation and 53BP1 accumulation

Autor: Yokomori, K, Tuzon, CT, Spektor, T, Kong, X, Cheung, P, Kuo, AJ, Congdon, LM, Schotta, G, Jasin, M, Gozani, O, Rice, JC

Publikováno v: Yokomori, K; Tuzon, CT; Spektor, T; Kong, X; Cheung, P; Kuo, AJ; et al.(2014). NHEJ-dependent recruitment of PR-Set7 to DNA double strand breaks facilitates H4K20 methylation and 53BP1 accumulation.. Cell Rep., [Epub]. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4n57j8t8
Cell Rep., vol [Epub]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4bcdcabe551a88de28086fada43f4945
http://www.escholarship.org/uc/item/4n57j8t8

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FGF signaling patterns cell fate at the interface between tendon and bone.

Autor: Roberts RR; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA.; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Bobzin L; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA.; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Teng CS; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, CA 90033, USA., Pal D; Research Division, Shriners Hospital for Children, Oregon Health & Science University, Portland, OR 97239, USA., Tuzon CT; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA.; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Schweitzer R; Research Division, Shriners Hospital for Children, Oregon Health & Science University, Portland, OR 97239, USA., Merrill AE; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA amerrill@usc.edu.; Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.

Autor: Neben CL; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry.; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Tuzon CT; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry.; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Mao X; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry.; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Lay FD; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Merrill AE; Center for Craniofacial Molecular Biology, Ostrow School of Dentistry.; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.

Autor: Bromberg KD; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Mitchell TR; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Upadhyay AK; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Jakob CG; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Jhala MA; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Comess KM; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Lasko LM; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Li C; Department of Immunology, University of Toronto, Medical Sciences Building, Toronto, Canada., Tuzon CT; Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA., Dai Y; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Li F; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Nuber A; Ludwig-Maximilians-Universität München and Munich Center for Integrated Protein Science (CiPSM), Biomedical Center, Planegg-Martinsried, Germany., Soni NB; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Manaves V; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Algire MA; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Sweis RF; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Torrent M; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Schotta G; Ludwig-Maximilians-Universität München and Munich Center for Integrated Protein Science (CiPSM), Biomedical Center, Planegg-Martinsried, Germany., Sun C; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Michaelides MR; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Shoemaker AR; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Santhakumar V; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Martin A; Department of Immunology, University of Toronto, Medical Sciences Building, Toronto, Canada., Rice JC; Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA., Chiang GG; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA.; eFFECTOR Therapeutics, San Diego, California, USA., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Pappano WN; Discovery, Research and Development, AbbVie, North Chicago, Illinois, USA.

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