Delayed DNase-I Administration but Not Gasdermin-D Inhibition Induces Hemorrhagic Transformation After Transient Focal Cerebral Ischemia in Mice.

Autor: Yin D; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).; Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.)., Wang C; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).; Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.)., Singh V; Institute of Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Germany (V.S., A.A.T., M.G.)., Tuz AA; Institute of Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Germany (V.S., A.A.T., M.G.)., Doeppner TR; Department of Neurology, University Hospital Gießen, Justus-Liebig-University Gießen, Germany (T.R.D.)., Gunzer M; Institute of Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Germany (V.S., A.A.T., M.G.).; Leibniz-Institut für Analytische Wissenschaften e.V. (ISAS), Dortmund, Germany (M.G.)., Hermann DM; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).; Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).

Publikováno v: Stroke [Stroke] 2024 Nov; Vol. 55 (11), pp. e297-e299. Date of Electronic Publication: 2024 Sep 30.

Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion.

Autor: Tuz AA; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Ghosh S; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany., Karsch L; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Ttoouli D; Bioinformatics and Computational Biophysics, Faculty of Biology and Centre for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany., Sata SP; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany., Ulusoy Ö; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Kraus A; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Hoerenbaum N; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Wolf JN; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Lohmann S; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Zwirnlein F; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Kaygusuz V; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Lakovic V; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Tummes HL; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Beer A; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Gallert M; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Thiebes S; Department of Immunodynamics, Institute of Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Qefalia A; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Cibir Z; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Antler M; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Korste S; Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital, University of Duisburg-Essen, Essen, Germany., Haj Yehia E; Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital, University of Duisburg-Essen, Essen, Germany., Michel L; Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital, University of Duisburg-Essen, Essen, Germany., Rassaf T; Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital, University of Duisburg-Essen, Essen, Germany., Kaltwasser B; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Abdelrahman H; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Mohamud Yusuf A; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Wang C; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Yin D; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Haeusler L; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Lueong S; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen), German Cancer Research Center (DKFZ), Heidelberg, Germany., Richter M; Institute for Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Universität Münster, Münster, Germany., Engel DR; Department of Immunodynamics, Institute of Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Stenzel M; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany., Soehnlein O; Institute for Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Universität Münster, Münster, Germany., Frank B; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Solo-Nomenjanahary M; Optimisation Thérapeutique en Neuropsychopharmacologie, Université Paris Cité, U1144 Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France., Ho-Tin-Noé B; Optimisation Thérapeutique en Neuropsychopharmacologie, Université Paris Cité, U1144 Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France., Siveke JT; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, partner site Essen), German Cancer Research Center (DKFZ), Heidelberg, Germany., Totzeck M; Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital, University of Duisburg-Essen, Essen, Germany., Hoffmann D; Bioinformatics and Computational Biophysics, Faculty of Biology and Centre for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany., Grüneboom A; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany., Hagemann N; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Hasenberg A; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany., Desilles JP; Optimisation Thérapeutique en Neuropsychopharmacologie, Université Paris Cité, U1144 Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.; Interventional Neuroradiology Department and Biological Resources Center, Rothschild Foundation Hospital, Paris, France., Mazighi M; Optimisation Thérapeutique en Neuropsychopharmacologie, Université Paris Cité, U1144 Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.; Interventional Neuroradiology Department and Biological Resources Center, Rothschild Foundation Hospital, Paris, France., Sickmann A; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany.; Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany.; Department of Chemistry, College of Physical Sciences, University of Aberdeen, Aberdeen, UK., Chen J; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany., Hermann DM; Department of Neurology, University Hospital, University of Duisburg-Essen, Essen, Germany., Gunzer M; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany. matthias.gunzer@uk-essen.de.; Leibniz-Institut für Analytische Wissenschaften - ISAS-e.V., Dortmund, Germany. matthias.gunzer@uk-essen.de., Singh V; Institute for Experimental Immunology and Imaging, University Hospital, University of Duisburg-Essen, Essen, Germany. vikramjeet.singh@uk-essen.de.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2024 May; Vol. 3 (5), pp. 525-540. Date of Electronic Publication: 2024 Apr 23.

Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs.

Autor: Spangenberg P; Department of Immunodynamics, Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany.; Center for Protein Diagnostics (ProDi), Ruhr-University Bochum, Bochum, Germany., Hagemann N; Department of Neurology, University Hospital Essen, Essen, Germany., Squire A; Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Förster N; Center for Protein Diagnostics (ProDi), Ruhr-University Bochum, Bochum, Germany.; Bioinformatics Group, Faculty for Biology and Biotechnology, Ruhr-University Bochum, Germany., Krauß SD; Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Qi Y; Department of Neurology, University Hospital Essen, Essen, Germany., Mohamud Yusuf A; Department of Neurology, University Hospital Essen, Essen, Germany., Wang J; Department of Neurology, University Hospital Essen, Essen, Germany., Grüneboom A; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Kowitz L; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Korste S; Department of Cardiology and Vascular Medicine, University Hospital Essen, Essen, Germany., Totzeck M; Department of Cardiology and Vascular Medicine, University Hospital Essen, Essen, Germany., Cibir Z; Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Tuz AA; Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Singh V; Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Siemes D; Department of Immunodynamics, Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Struensee L; Center for Protein Diagnostics (ProDi), Ruhr-University Bochum, Bochum, Germany., Engel DR; Department of Immunodynamics, Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany., Ludewig P; Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Martins Nascentes Melo L; Clinic of Dermatology, University Hospital Essen, Essen, Germany., Helfrich I; Clinic of Dermatology, University Hospital Essen, Essen, Germany., Chen J; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Gunzer M; Institute for Experimental Immunology and Imaging, University Hospital Essen, Essen, Germany.; Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany., Hermann DM; Department of Neurology, University Hospital Essen, Essen, Germany., Mosig A; Center for Protein Diagnostics (ProDi), Ruhr-University Bochum, Bochum, Germany.; Bioinformatics Group, Faculty for Biology and Biotechnology, Ruhr-University Bochum, Germany.

Publikováno v: Cell reports methods [Cell Rep Methods] 2023 Mar 17; Vol. 3 (3), pp. 100436. Date of Electronic Publication: 2023 Mar 17 (Print Publication: 2023).

Coronavirus Disease 2019 in Patients with Asthma: Case Study from a Tertiary Center Regarding Their Phenotypes and Their Adherence to Asthma Treatment by Telemedicine.

Autor: Çalışkaner Öztürk B; Department of Pulmonary Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey., Güngördü Mazıcan N; Department of Pulmonary Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey., Çalışkan EB; Department of Pulmonary Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey., Tuz AA; Department of Pulmonary Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey., Gemicioğlu B; Department of Pulmonary Diseases, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey.

Publikováno v: Turkish thoracic journal [Turk Thorac J] 2022 Jan; Vol. 23 (1), pp. 25-31.