Výsledky vyhledávání - "Tuysuz, E.C."

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Co-polysomy of 1p/19q in glial tumors: Retrospective analysis of 221 cases from single center

Autor: Kuskucu, A., Tuysuz, E.C., Gurkan, S., Demir, Z., Yaltirik, C.K., Ozkan, F., Ture, U.

Glial tumors are malignant brain tumors that arise from glial cells of brain or spine and have genetic aberrations in their genome. 1p/19q co-deletion is associated with increased Overall Survival (OS) time with enhanced response to chemo- and radio-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::f0841549524e4bcad471945e6980ecf8
https://hdl.handle.net/20.500.11831/848

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Distinctive role of dysregulated miRNAs in chordoma cancer stem-like cell maintenance

Autor: Tuysuz, E.C., Gulluoglu, S., Yaltirik, C.K., Ozbey, U., Kuskucu, A., Çoban, E.A., Bayrak, O.F.

Chordoma is a rare, slow-growing tumor thought to arise from remnants of embryonic notochord associated with an aggressive outcome. Cancer stem-like cells (CSCs)are related to tumorigenesis, recurrence, and resistance in cancers. Therefore, chordoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::3ee2fc97cac3e6b852c88c7ac0982f10
https://hdl.handle.net/20.500.11831/3690

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The role of TNF-? in chordoma progression and inflammatory pathways

Autor: Gulluoglu, S., Tuysuz, E.C., Sahin, M., Yaltirik, C.K., Kuskucu, A., Ozkan, F., Bayrak, O.F.

Purpose: Chordomas are highly therapy-resistant primary bone tumors that exhibit high relapse rates and may induce local destruction. Here, we evaluated the effects of tumor necrosis factor-alpha (TNF-?) on chordoma progression and clinical outcome.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::976581c11f65bd5c81fe41350b2b2884
https://hdl.handle.net/20.500.11831/1718

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Smooth muscle cell differentiation from rabbit amniotic cells

Autor: Senel, U., Coskun, O.S., Tuysuz, E.C., Sahin, M., Bayrak, O.F., Cakmak, B., Kuskucu, A.

Amniotic fluid (AF) is the liquid layer that provides mechanical support and allows movement of the fetus during embryogenesis. Mesenchymal stem cells (MSCs), which have differentiation capacity, are also found in AF-derived cells at a low ratio. Smo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::49ba2568712026c91fd6954396c04e0c
https://hdl.handle.net/20.500.11831/3693

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Simultaneous miRNA and mRNA transcriptome profiling of glioblastoma samples reveals a novel set of OncomiR candidates and their target genes

Autor: Gulluoglu, S., Tuysuz, E.C., Sahin, M., Kuskucu, A., Kaan Yaltirik, C., Ture, U., Dalan, A.B.

Although glioblastomas are common, there remains a need to elucidate the underlying mechanisms behind their initiation and progression and identify molecular pathways for improving treatment. In this study, sixteen fresh-frozen glioblastoma samples a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::94f46fd2f1f9e997ca5059e229545b07
https://hdl.handle.net/20.500.11831/650

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Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c

Autor: Dalan, A.B., Gulluoglu, S., Tuysuz, E.C., Kuskucu, A., Yaltirik, C.K., Ozturk, O., Bayrak, O.F.

Background: Although meningioma is a common disease, there is a lack of understanding of the underlying molecular mechanisms behind its initiation and progression. We used combined miRNA-mRNA transcriptome analysis to discover dysregulated genes and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::ce39c7062620ec1611b170e90cc23fc6
https://hdl.handle.net/20.500.11831/3588

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A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/ß-catenin pathway

Autor: Doğan, A., Demirci, S., Apdik, H., Bayrak, O.F., Gulluoglu, S., Tuysuz, E.C., Şahin, Fikrettin

Obesity is a worldwide medical problem resulting in serious morbidity and mortality involving differentiation of pre-adipocytes into mature adipocytes (adipogenesis). Boron treatment has been reported to be associated with weight reduction in experim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::69b917ac381c3b9559ce39751901c3ed
https://hdl.handle.net/20.500.11831/1397

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Leukemia inhibitory factor promotes aggressiveness of Chordoma

Autor: Gulluoglu, S., Sahin, M., Tuysuz, E.C., Yaltirik, C.K., Kuskucu, A., Ozkan, F., Bayrak, O.F.

Chordomas are rare tumors of the spine and skull base that are locally destructive and resistant to chemotherapy and radiation therapy, with a poor prognosis and limited therapeutic options. Chordoma patients have a long life expectancy with high mor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10007::845cf5dac8c329c081daf3f59d0443e1
https://hdl.handle.net/20.500.11831/107

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