Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Tuyet-Hang Pham"'
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 9, Pp n/a-n/a (2022)
Abstract Objectives A subset of chronic obstructive pulmonary disease (COPD) patients have increased numbers of airway eosinophils associated with elevated markers of T2 inflammation. This analysis focussed on mast cell counts and mast cell‐related
Externí odkaz:
https://doaj.org/article/282a9301448549498729db524e7334d5
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Benralizumab, a humanized, afucosylated, monoclonal antibody that targets interleukin-5 receptor α, depletes eosinophils and basophils by enhanced antibody-dependent cell-mediated cytotoxicity. It demonstrated efficacy for patien
Externí odkaz:
https://doaj.org/article/90a089f740a64c94927d146811d4e10a
Autor:
Vamsi P, Guntur, Laurie A, Manka, Camille M, Moore, Elizabeth, Wynn, Eszter K, Vladar, Rafeul, Alam, Tuyet-Hang, Pham, Tasha E, Fingerlin, Richard J, Martin
Publikováno v:
Journal of Allergy and Clinical Immunology. 149:1970-1980
Refractory asthma (RA) remains poorly controlled, resulting in high health care utilization despite guideline-based therapies. Patients with RA manifest higher neutrophilia as a result of increased airway inflammation and subclinical infection, the u
Autor:
Jonathan, Corren, Tuyet-Hang, Pham, Esther, Garcia Gil, Kinga, Sałapa, Pin, Ren, Jane R, Parnes, Gene, Colice, Janet M, Griffiths
Publikováno v:
Allergy. 77:1786-1796
Tezepelumab is a human monoclonal antibody that blocks activity of thymic stromal lymphopoietin (TSLP). In the phase IIb PATHWAY study (NCT02054130), tezepelumab significantly reduced annualized asthma exacerbation rates (AAERs) versus placebo in adu
Publikováno v:
Annals of Allergy, Asthma & Immunology. 127:689-691
Akademický článek
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Akademický článek
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Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-12 (2019)
Respiratory Research
Respiratory Research
Background Benralizumab, a humanized, afucosylated, monoclonal antibody that targets interleukin-5 receptor α, depletes eosinophils and basophils by enhanced antibody-dependent cell-mediated cytotoxicity. It demonstrated efficacy for patients with m
Publikováno v:
Immunology and Allergy Clinics of North America. 38:611-628
Periostin and dipeptidyl peptidase-4 (DPP-4) are proteins induced by type 2 cytokines interleukin (IL)-4 and IL-13 and show increased expression in asthma and diseases with type 2 inflammation, including atopic dermatitis and chronic rhinosinusitis.
Autor:
Josiah V Dungwa, Sriram Sridhar, Umme Kolsum, Paul Newbold, Jian Li, Thomas Scott, Dave Singh, Andrew Higham, Thomas Southworth, Tuyet-Hang Pham
Publikováno v:
Southworth, T, Higham, A, Kolsum, U, Li, J, Scott, T, Dungwa, J, Sridhar, S, Pham, TH, Newbold, P & Singh, D 2021, ' The relationship between airway immunoglobulin activity and eosinophils in COPD ', Journal of cellular and molecular medicine, vol. 25, no. 4, pp. 2203-2212 . https://doi.org/10.1111/jcmm.16206
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine
In chronic obstructive pulmonary disease (COPD), the effects of inhaled corticosteroids are predicted by blood eosinophil counts. We previously briefly reported increased immunoglobulin (Ig)A and IgM levels in bronchoalveolar lavage (BAL) of COPD pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce151ff8a5f477226fe932d9309276d
https://www.research.manchester.ac.uk/portal/en/publications/the-relationship-between-airway-immunoglobulin-activity-and-eosinophils-in-copd(6b345be9-aa13-4d4b-8fc2-26be1aa73a92).html
https://www.research.manchester.ac.uk/portal/en/publications/the-relationship-between-airway-immunoglobulin-activity-and-eosinophils-in-copd(6b345be9-aa13-4d4b-8fc2-26be1aa73a92).html