Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Tuvia Gilat"'
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 1, Pp 114-119 (2001)
A simple, sensitive, and specific liquid chromatography-electrospray tandem mass spectrometry (LC-MS/MS) method for the determination of bile acids in human bile has been developed. The bile acids were extracted with a C18 (octadecyl) reversed-phase
Externí odkaz:
https://doaj.org/article/af3ed416bf874802b54e2211215282ae
Autor:
Tuvia Gilat, Fred Konikoff
Publikováno v:
Canadian Journal of Gastroenterology, Vol 14, Iss Suppl D, Pp 55D-59D (2000)
Pregnancy induces many physiological changes, some of which may have pathological results. In population studies, gallstones were found in 6.5% to 8.4% of nulliparous women, and in 18.4% to 19.3% of women with two to three or more pregnancies. In wom
Externí odkaz:
https://doaj.org/article/c950b2db6882474fa9ea0d83aca3b2ef
Publikováno v:
Liver. 10:173-176
— Lithogenicity of human bile is dependent not only on cholesterol saturation, but also on the presence of nucleating and antinucleating factors. Most of the research in this field is directed toward biliary proteins, particularly glycoproteins. In
Autor:
Tuvia Gilat, Zamir Halpern, Y Peled, J Rattan, Gideon Goldman, Dov Lichtenberg, Fred M. Konikoff
Publikováno v:
Liver. 12:107-111
Nucleating factors are thought to be responsible for the more rapid nucleation of gallbladder bile from patients with gallstones as compared to controls. Biliary proteins and, in particular, mucus and non-mucus glycoproteins are the focus of current
Autor:
Christine Juhel, Fred M. Konikoff, Tuvia Gilat, Ilana Goldiner, Diana Gobbi, Alicia Leikin-Frenkel, Huguette Lafont
Publikováno v:
Hepatology. 38:436-442
Fatty acid bile acid conjugates (FABACs) are a new family of synthetic molecules designed to solubilize biliary cholesterol. They were shown to prevent and dissolve cholesterol gallstones in inbred C57L/J mice fed a lithogenic, high-fat diet (HFD). I
Publikováno v:
Hepatology. 35:597-600
Gallstones, mostly cholesterol stones, affect some 15% of the population. Oral bile salts dissolve human cholesterol gallstones, but with low efficacy, and surgery remains the main therapeutic option. Fatty acid bile acid conjugates (FABACs) were sho
Autor:
Zamir Halpern, Alicia Leikin-Frenkel, Hava Laufer, Ilana Goldiner, Fred M. Konikoff, Tuvia Gilat
Publikováno v:
Lipids. 36:1135-1140
We have recently synthesized fatty acid bile acid conjugates (FABAC) that were able to reduce and retard cholesterol crystallization in model and human biles. When given orally, they prevented the formation of cholesterol crystals in the bile of hams
Autor:
Fred M. Konikoff, Zamir Halpern, G J Somjen, R Rosenberg, Tuvia Gilat, A Leikin-Frenkel, Y Mazur
Publikováno v:
Gut. 48:75-79
BACKGROUND—Cholesterol gall stones are a frequent disease for which at present surgery is the usual therapy. Despite the importance of bile acids it has become evident that phospholipids are the main cholesterol solubilisers in bile. Even phospholi
Autor:
Yael Villa, Tuvia Gilat, Nadir Arber, Rami Eliakim, Alexandra Lavy, Julian Paz, Shimon Reif, Alexander Fich, Yaron Niv, Efrat Broide, Yulia Ron, D. Keter, Aharon Halak, Odes Hs
Publikováno v:
Digestive Diseases and Sciences. 46:1717-1721
Cigarette smoking worsens Crohn's disease (CD) but ameliorates ulcerative colitis (UC). In Israel, where there is no epidemiological association of smoking with CD, we examined the effects of current smoking on the course of CD and UC. Patients at ni
Autor:
Shmuel Odes, Alexander Fich, Shimon Reif, Yishai Ron, Tuvia Gilat, Efrat Broide, D. Keter, Aharon Halak, Rami Eliakim, Alexandra Lavy, Julian Paz, Yael Villa, Yaron Niv
Publikováno v:
European Journal of Gastroenterology & Hepatology. 12:975-979
Background The association between smoking and inflammatory bowel disease (IBD) is well established. There are, however, no large scale studies of passive smoking in inflammatory bowel disease and this has never been surveyed in the Jewish population