In-depth analysis of transcriptomes in ovarian cortical follicles from children and adults reveals interfollicular heterogeneity.

Autor: Rooda I; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden. ilmatar.rooda@ki.se.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden. ilmatar.rooda@ki.se.; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia. ilmatar.rooda@ki.se., Hassan J; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Hao J; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.; Department of Reproductive Medicine, Xiangya Hospital, Central South University, Changsha, PR China., Wagner M; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Moussaud-Lamodière E; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Jääger K; Institute of Computer Science, University of Tartu, Tartu, Estonia.; Competence Centre on Health Technologies, Tartu, Estonia., Otala M; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Knuus K; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Lindskog C; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Papaikonomou K; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Gidlöf S; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Langenskiöld C; Department of Pediatric Oncology, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden., Vogt H; Crown Princess Victoria Children's Hospital, and Division of Children's and Women's Health, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Frisk P; Department of Women's and Children's Health, Uppsala University Children's Hospital, Uppsala, Sweden., Malmros J; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Tuuri T; Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Salumets A; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.; Competence Centre on Health Technologies, Tartu, Estonia.; Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia., Jahnukainen K; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Women's and Children's Health, NORDFERTIL Research Lab Stockholm, Karolinska Institutet and University Hospital, Stockholm, Sweden., Velthut-Meikas A; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia., Damdimopoulou P; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Huddinge, Stockholm, Sweden. pauliina.damdimopoulou@ki.se.; Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden. pauliina.damdimopoulou@ki.se.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 21; Vol. 15 (1), pp. 6989. Date of Electronic Publication: 2024 Aug 21.

Correction to: Induced Pluripotent Stem Cells as a Possible Approach for Exploring the Pathophysiology of Polycystic Ovary Syndrome (PCOS).

Autor: Khatun M; Department of Obstetrics and Gynecology, University of Helsinki, Helsinki University Central Hospital, Haartmaninkatu 8, 00029 HUS, Helsinki, Finland. masuma.khatun@helsinki.fi., Lundin K; Department of Obstetrics and Gynecology, University of Helsinki, Helsinki University Central Hospital, Haartmaninkatu 8, 00029 HUS, Helsinki, Finland., Naillat F; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland., Loog L; Institute of Genomics, University of Tartu, 51010, Tartu, Estonia.; Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK., Saarela U; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Tuuri T; Department of Obstetrics and Gynecology, University of Helsinki, Helsinki University Central Hospital, Haartmaninkatu 8, 00029 HUS, Helsinki, Finland., Salumets A; Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tartu, 50406, Tartu, Estonia.; Competence Centre of Health Technologies, 50411, Tartu, Estonia.; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, 14186, Huddinge, Stockholm, Sweden., Piltonen TT; Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center, Oulu University Hospital, University of Oulu, Oulu, Finland., Tapanainen JS; Department of Obstetrics and Gynecology, University of Helsinki, Helsinki University Central Hospital, Haartmaninkatu 8, 00029 HUS, Helsinki, Finland.; Department of Obstetrics and Gynecology, HFR - Cantonal Hospital of Fribourg and University of Fribourg, Fribourg, Switzerland.

Publikováno v: Stem cell reviews and reports [Stem Cell Rev Rep] 2024 Feb; Vol. 20 (2), pp. 583.

Reference standards for follicular density in ovarian cortex from birth to sexual maturity.

Autor: Hassan J; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynaecology, Karolinska Institutet, Stockholm, Sweden; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden. Electronic address: jasmin.hassan@ki.se., Knuus K; Department of Obstetrics and Gynaecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Lahtinen A; Applied Tumour Genomics Research Programme, Faculty of Medicine, University of Helsinki, Finland; Department of Medical and Clinical Genetics, Medicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Rooda I; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynaecology, Karolinska Institutet, Stockholm, Sweden; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Otala M; University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Tuuri T; Department of Obstetrics and Gynaecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Gidlöf S; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynaecology, Karolinska Institutet, Stockholm, Sweden; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Edlund E; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Menezes J; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Malmros J; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Byström P; Department of Clinical Science, Intervention and Technology, Division of Paediatrics, Karolinska Institutet, Stockholm, Sweden; Section of Paediatric Haematology, Immunology and HCT, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Sundin M; Department of Clinical Science, Intervention and Technology, Division of Paediatrics, Karolinska Institutet, Stockholm, Sweden; Section of Paediatric Haematology, Immunology and HCT, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Langenskiöld C; Department of Paediatric Oncology, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden., Vogt H; Crown Princess Victoria's Child and Youth Hospital, Linköping, Sweden; Department of Biomedical and Clinical Sciences, Division of Children's and Women's Health, Linköping University, Linköping, Sweden., Frisk P; Department of Women's and Children's Health, Uppsala University Children's Hospital, Uppsala, Sweden., Petersen C; NORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Department of Paediatric Oncology, Karolinska University Hospital, Stockholm, Sweden., Damdimopoulou P; Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynaecology, Karolinska Institutet, Stockholm, Sweden; Department of Gynaecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden., Jahnukainen K; NORDFERTIL Research Lab Stockholm, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Children's Hospital, Paediatric Research Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Publikováno v: Reproductive biomedicine online [Reprod Biomed Online] 2023 Oct; Vol. 47 (4), pp. 103287. Date of Electronic Publication: 2023 Jul 17.

Human pluripotent stem cell-derived cells endogenously expressing follicle-stimulating hormone receptors:modeling the function of an inactivating receptor mutation

Autor: Lundin, K. (K.), Sepponen, K. (K.), Väyrynen, P. (P.), Liu, X. (X.), Yohannes, D. A. (D. A.), Survila, M. (M.), Ghimire, B. (B.), Känsäkoski, J. (J.), Katayama, S. (S.), Partanen, J. (J.), Vuoristo, S. (S.), Paloviita, P. (P.), Rahman, N. (N.), Raivio, T. (T.), Luiro, K. (K.), Huhtaniemi, I. (I.), Varjosalo, M. (M.), Tuuri, T. (T.), Tapanainen, J. S. (J. S.)

Follicle-stimulating hormone (FSH) is crucial in the development and regulation of reproductive functions. The actions of human FSH and its receptor (FSHR) and mutations therein have mainly been studied using in vivo models, primary cells, cancer cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2423::6d9d42673809e334cefc3ce37ae4ff3c
https://massive.ucsd.edu/

Small RNA expression and miRNA modification dynamics in human oocytes and early embryos

Autor: Paloviita, P. (Pauliina), Hydén-Granskog, C. (Christel), Yohannes, D. A. (Dawit A.), Paluoja, P. (Priit), Kere, J. (Juha), Tapanainen, J. S. (Juha S.), Krjutškov, K. (Kaarel), Tuuri, T. (Timo), Võsa, U. (Urmo), Vuoristo, S. (Sanna)

Small noncoding RNAs (sRNAs) play important roles during the oocyte-to-embryo transition (OET), when the maternal phenotype is reprogrammed and the embryo genome is gradually activated. The transcriptional program driving early human development has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2423::422e53207115afaf2645367ec42b664c
http://urn.fi/urn:nbn:fi-fe2021122262946