Elevated Serum Anti-Saccharomyces cerevisiae, Anti-I2 and Anti-OmpW Antibody Levels in Patients with Suspicion of Celiac Disease

Autor: Jonathan Braun, Merja Ashorn, Bo Wei, Pekka Collin, Katri Kaukinen, Hanna Raukola, Tiina Luukkaala, Markku Mäki, Sari Iltanen, Tuuli Välineva, Sara Ashorn, Immo Rantala

Publikováno v: Journal of Clinical Immunology. 28:486-494

Expression of anti-Saccharomyces cerevisiae antibodies (ASCA) identifies patients and individuals at risk for Crohn's disease and has also been reported in 40-60% of celiac disease (CD) cases, suggesting a role of host response to enteric microbiota

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3558c99d87a3378a397b6296d5303997
https://doi.org/10.1007/s10875-008-9200-9

The Transcriptional Co-activator Protein p100 Recruits Histone Acetyltransferase Activity to STAT6 and Mediates Interaction between the CREB-binding Protein and STAT6

Autor: Riitta Palovuori, Jie Yang, Tuuli Välineva, Olli Silvennoinen

Publikováno v: Journal of Biological Chemistry. 280:14989-14996

STAT6 is a critical regulator of transcription for interleukin-4 (IL-4)-induced genes. Activation of gene expression involves recruitment of coactivator proteins that function as bridging factors connecting sequence-specific transcription factors to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76566edb8342d35e6ae3d8e32a11124a
https://doi.org/10.1074/jbc.m410465200

Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome

Autor: Juha Saarikettu, Anna Golovko, Andrey A. Zamyatnin, Peter V. Bozhkov, Tuuli Välineva, Eugene I. Savenkov, Eva Sundberg, Olli Silvennoinen, Budhi Sagar Tiwari, Ulf Stahl, Alena Vaculova, Andrei Smertenko, Elena A. Minina, Maria F. Suarez, Boris Zhivotovsky, Anton V. Zavialov, Salvador Rodriguez-Nieto, Jens F. Sundström, Patrick J. Hussey, Mikko J. Frilander

Publikováno v: Nature cell biology. 11(11)

Programmed cell death (PCD) is executed by proteases, which cleave diverse proteins thus modulating their biochemical and cellular functions. Proteases of the caspase family and hundreds of caspase substrates constitute a major part of the PCD degrad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7511719aeb12b03e2b9dec1eee2f2397
https://pubmed.ncbi.nlm.nih.gov/19820703

Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome

Autor: Ole N. Jensen, Jie Yang, Olli Silvennoinen, Mikko J. Frilander, Jingxin Hong, Zhi Yao, Tianxu Bu, Tuuli Välineva

Publikováno v: Yang, J, Valineva, T, Hong, J, Bu, T, Zao, Z, Jensen, O N, Frilander, MJ & Silvennoinen, O 2007, ' Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome ', Nucleic Acids Research, vol. 35, no. 13, pp. 4485-4494 . https://doi.org/10.1093/nar/gkm470
Nucleic Acids Research

Transcription and pre-mRNA splicing are the key nuclear processes in eukaryotic gene expression, and identification of factors common to both processes has suggested that they are functionally coordinated. p100 protein has been shown to function as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e037d00c28926602d27070e98aa36b
https://portal.findresearcher.sdu.dk/da/publications/998ee150-d4b1-11dc-b2ba-000ea68e967b

Elevated Serum Anti- Saccharomyces cerevisiae , Anti-I2 and Anti-OmpW Antibody Levels in Patients with Suspicion of Celiac Disease.

Autor: Sara Ashorn, Hanna Raukola, Tuuli Välineva, Bo Wei, Jonathan Braun, Immo Rantala, Tiina Luukkaala, Pekka Collin

Publikováno v: Journal of Clinical Immunology; Sep2008, Vol. 28 Issue 5, p486-494, 9p