UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice

Autor: Daniel Ryskamp Rijsketic, Austen B. Casey, Daniel A. N. Barbosa, Xue Zhang, Tuuli M. Hietamies, Grecia Ramirez-Ovalle, Matthew B. Pomrenze, Casey H. Halpern, Leanne M. Williams, Robert C. Malenka, Boris D. Heifets

Publikováno v: bioRxiv

The effects of context on the subjective experience of serotonergic psychedelics have not been fully examined in human neuroimaging studies, partly due to limitations of the imaging environment. Here, we administered saline or psilocybin to mice in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbb028a2780211f796c748bbf4f67a4
https://europepmc.org/articles/PMC9980055/

Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia

Autor: Gabriel Martínez, Ríona Mc Ardle, Emma Elliott, Zoë Tieges, Terry J Quinn, Tuuli M Hietamies

Publikováno v: Quinn, T, Elliot, E, Hietamies, T, Martinez, G, Tieges, Z & Mc Ardle, R 2020, ' Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia ', Cochrane Database of Systematic Reviews . https://doi.org/10.1002/14651858.CD013724

ObjectivesThis is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:Our main objective is to assess the test accuracy of any multidomain cognitive test delivered remotely for the diagnosis of any form of dementia.Our review

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a556ee0162d7a06892dd928eaefbd4c6
https://doi.org/10.1002/14651858.cd013724

UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment : questionnaire and workshop proceedings

Autor: Malcolm R. Macleod, Margaux Aimable, Scott Miners, Matthew MacGregor Sharp, Hilary V O Carswell, Philip M.W. Bath, Ashton Bernard, Emily S. Sena, Claire S. White, Rhian M. Touyz, Patrick G. Kehoe, Tracy D. Farr, Lorraine M. Work, Stefan Szymkowiak, Gillian L. Currie, Catherine N. Hall, Bettina Platt, Andrew N. Clarkson, Gaia Brezzo, Stuart M. Allan, Mark Andrew Good, Roxana O. Carare, Alison D. McNeilly, Alyson A. Miller, Jill H. Fowler, Barry W. McColl, Tuuli M Hietamies, Christopher McCabe, Rebecca C. Trueman, Vincent Mok, Rajesh N. Kalaria, Michael O'Sullivan, Terence J. Quinn, Karen Horsburgh, Atticus H. Hainsworth, Patrick Strangeward, Catherine E. Lawrence, Aisling McFall

Publikováno v: McFall, A, Hietamies, T M, Bernard, A, Aimable, M, Allan, S M, Bath, P M, Brezzo, G, Carare, R O, Carswell, H V, Clarkson, A N, Currie, G, Farr, T D, Fowler, J, Good, M, Hainsworth, A H, Hall, C, Horsburgh, K, Kalaria, R, Kehoe, P, Lawrence, C, MacLeod, M, McNeilly, A, Miller, A A, Miners, S, Mok, V, O'Sullivan, M, Platt, B, Sena, E, Sharp, M, Strangeward, P, Szymkowiak, S, Touyz, R M, Trueman, R C, White, C, McCabe, C, Work, L M & Quinn, T J 2020, ' UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings ', Journal of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678X20910552
Journal of Cerebral Blood Flow & Metabolism
McFall, A, Hietamies, T M, Bernard, A, Aimable, M, Allan, S M, Bath, P M, Brezzo, G, Carare, R O, Carswell, H V, Clarkson, A N, Currie, G, Farr, T D, Fowler, J H, Good, M, Hainsworth, A H, Hall, C, Horsburgh, K, Kalaria, R, Kehoe, P, Lawrence, C, Macleod, M, McColl, B W, McNeilly, A, Miller, A A, Miners, S, Mok, V, O'Sullivan, M, Platt, B, Sena, E S, Sharp, M, Strangeward, P, Szymkowiak, S, Touyz, R M, Trueman, R C, White, C, McCabe, C, Work, L M & Quinn, T J 2020, ' UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment : questionnaire and workshop proceedings ', Journal of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678X20910552

Assessment of outcome in preclinical studies of vascular cognitive impairment (VCI) is heterogenous. Through an ARUK Scottish Network supported questionnaire and workshop (mostly UK-based researchers), we aimed to determine underlying variability and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eef0fbd3bfb3e2bea0c06634a444e02
https://strathprints.strath.ac.uk/71920/7/McFall_etal_JCBFM_2020_UK_consensus_on_pre_clinical_vascular_cognitive.pdf

Abstract TP420: Variability in Functional Outcome Measures Used in Contemporary Animal Models of Stroke and Vascular Cognitive Impairment

Autor: Pei Zhong, Terence J. Quinn, Lorraine M. Work, Luyang Feng, Tuuli M Hietamies, Caroline Ostrowski

Publikováno v: Stroke. 49

Functional measures are recommended as primary outcome within clinical stroke trials but there is substantial heterogeneity in the assessments used. There may be a similar lack of consistency to outcome assessment in preclinical studies. Our aim was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b649c26fd35547e6d42625e393faea13
https://doi.org/10.1161/str.49.suppl_1.tp420