Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tuula Kuukasjärvi"'
Autor:
Kirsi Syrjäkoski, Tuula Kuukasjärvi, Kati Waltering, Karin Haraldsson, Anssi Auvinen, Åke Borg, Tommi Kainu, Olli-P Kallioniemi, Pasi A. Koivisto
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 5, Pp 541-545 (2004)
The etiology and pathogenesis of male breast cancer (MBC) are poorly known. This is due to the fact that the disease is rare, and large-scale genetic epidemiologic studies have been difficult to carry out. Here, we studied the frequency of eight recu
Externí odkaz:
https://doaj.org/article/0ec309226fc14aeeaeead309f6e3816f
Autor:
Kaija Holli, Emma-Leena Alarmo, Seppo Parkkila, Liisa Pylkkänen, Tarja Korhonen, Heini Huhtala, Tuula Kuukasjärvi, Anne Kallioniemi
Publikováno v:
Modern Pathology. 26(1):10-21
Bone morphogenetic proteins (BMPs) are extracellular signaling molecules that belong to the transforming growth factor β (TGFβ) superfamily and are known to regulate cell proliferation, differentiation and motility, especially during development. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aacbceb5f27c473ecbbc5d6b61170f5
http://juuli.fi/Record/0039843613
http://juuli.fi/Record/0039843613
Publikováno v:
British Journal of Cancer
Increased copy numbers of 17q23 chromosomal region have been shown to occur in different tumour types and to be associated with tumour progression and with poor prognosis. Several genes have earlier been proposed as potential oncogenes at this region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3e4f1691f37dac8c2fdf5b31422f2f
https://doi.org/10.1038/sj.bjc.6603692
https://doi.org/10.1038/sj.bjc.6603692
Publikováno v:
Breast Cancer Research and Treatment. 103:239-246
Bone morphogenetic proteins (BMPs) regulate diverse cellular processes, such as proliferation, differentiation, and apoptosis. The BMPs have been studied in several cancers, but thus far contradictory results have been obtained and, especially in bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e12380d658b529dccfd83950ef3dbe1
https://doi.org/10.1007/s10549-006-9362-1
https://doi.org/10.1007/s10549-006-9362-1
Autor:
Ritva Karhu, Emma-Leena Alarmo, Tuula Kuukasjärvi, Jenita Rauta, Anne Kallioniemi, Päivikki Kauraniemi
Publikováno v:
Genes, Chromosomes and Cancer. 45:411-419
Bone morphogenetic proteins (BMP) make up a family of extracellular signaling molecules that play a critical role in vertebrate development and both inhibit and stimulate growth in cancer cells. BMP7 was recently identified in our genomewide copy num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f0cc45b6156d4d5cff72425e2947c7
https://doi.org/10.1002/gcc.20307
https://doi.org/10.1002/gcc.20307
Autor:
Anne Kallioniemi, Ritva Karhu, Tuula Kuukasjärvi, Päivikki Kauraniemi, Emma-Leena Alarmo, Jenita Rauta
Publikováno v:
Breast Cancer Research and Treatment. 95:257-263
The serine-threonine protein phosphatase PPM1D is likely to play an important role in tumorigenesis. Through inactivation of p38 MAPK, PPM1D acts as a negative feedback regulator of p53 tumour suppressor gene and controls the expression of other cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475caef1cc9d591684056c8f05077202
https://doi.org/10.1007/s10549-005-9017-7
https://doi.org/10.1007/s10549-005-9017-7
Publikováno v:
International Journal of Cancer. 111:968-971
Genetic events underlying the pathogenesis of breast cancer have been studied extensively and several clinically significant markers have been identified. For example, amplification and overexpression of the ERBB2 oncogene is associated with poor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cd1e45f149f652fec01d58b7e4b7ef5
https://doi.org/10.1002/ijc.20307
https://doi.org/10.1002/ijc.20307
Publikováno v:
Scopus-Elsevier
Amplification of the ERBB2 oncogene at 17q12 is clinically the most relevant genetic aberration in breast cancer and several studies have linked ERBB2 activation to poor clinical outcome. The development of targeted antibody-based therapy for ERBB2-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c38a6cabbaf76aa99a78f49a96af22
https://doi.org/10.1016/s0002-9440(10)63556-0
https://doi.org/10.1016/s0002-9440(10)63556-0
Autor:
Johanna Schleutker, Mika P. Matikainen, Tuula Kuukasjärvi, Annika Rökman, Heikki Helin, Marita Poutiainen, Ritva Karhu, Pasi A. Koivisto, Olli-P. Kallioniemi
Publikováno v:
The Prostate. 46:233-239
Background Germline mutations in recessive cancer predisposition genes are uncovered by somatic genetic deletions during tumor development. Analysis of genetic changes in tumor tissues from patients with an inherited predisposition may therefore high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00aafa329885124c5a400dea6273f482
https://doi.org/10.1002/1097-0045(20010215)46:3<233::aid-pros1028>3.0.co
https://doi.org/10.1002/1097-0045(20010215)46:3<233::aid-pros1028>3.0.co
Autor:
Pasi A. Koivisto, Johanna Schleutker, Mika P. Matikainen, Teuvo L.J. Tammela, Kirsi Syrjäkoski, Henna Fredriksson, Tuula Kuukasjärvi, Tarja Ikonen, Ville Autio
Publikováno v:
International Journal of Cancer. 118:518-520
Hereditary hemochromatosis (HH), the most common genetic disease in northern Europeans, is an autosomal recessive disorder of iron metabolism. The association between hepatocellular carcinoma and HFE homozygosity is well documented, but recently HFE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c690dea4ee559fe16503e9feb7f9109b
https://doi.org/10.1002/ijc.21331
https://doi.org/10.1002/ijc.21331