Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Tuula Janatuinen"'
Autor:
Jarna C. Hannukainen, Kari K. Kalliokoski, Jaakko Kaprio, Pirjo Nuutila, Olli J. Heinonen, Patricia Iozzo, Urho M. Kujala, Tapio Viljanen, Antti Viljanen, R. Borra, Tuula Janatuinen, Riitta Parkkola, Merja Haaparanta
Publikováno v:
Obesity, 18(2), 261-265. Wiley-Blackwell
Visceral adipose tissue has been shown to have high lipolytic activity. The aim of this study was to examine whether free fatty acid (FFA) uptake into visceral adipose tissue is enhanced compared to abdominal subcutaneous tissue in vivo. Abdominal ad
Autor:
Juhani Knuuti, Stefan Lundt, Riikka Kalliokoski, Kari K. Kalliokoski, Tuula Janatuinen, Juha Koskenvuo, Jarna C. Hannukainen
Publikováno v:
The American Journal of Cardiology. 99:1648-1652
Recent randomized clinical studies failed to show cardiovascular protection with postmenopausal hormone therapy (HT), instead raising widespread concerns about possible increased cardiovascular risk. However, these studies primarily assessed the comb
Autor:
Tuula Janatuinen, Terho Lehtimäki, Pekka J. Karhunen, Juhani Knuuti, Erkki Ilveskoski, Reijo Laaksonen, Risto Vesalainen, Pekka Laippala, Pirjo Nuutila
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 67:723-734
Apolipoprotein E (apoE) polymorphism affects the risk of advanced coronary artery disease, but its role in early atherosclerosis remains unknown. We used positron emission tomography (PET) to study whether coronary reactivity or its response to prava
Autor:
Tapio Viljanen, Tuula Janatuinen, Olli J. Heinonen, Juhani Knuuti, Jaakko Kaprio, Borra Ronald, Urho M. Kujala, Pirjo Nuutila, Tapani Rönnemaa, Merja Haaparanta, Jarna C. Hannukainen, Jukka Kapanen, Kari K. Kalliokoski, Riitta Parkkola
Publikováno v:
The Journal of Physiology. 578:347-358
Exercise is considered to be beneficial for free fatty acid (FFA) metabolism, although reports of the effects of increased physical activity on FFA uptake and oxidation in different tissues in vivo in humans have been inconsistent. To investigate the
Autor:
Urho M. Kujala, Jarna C. Hannukainen, Tapio Viljanen, Merja Haaparanta-Solin, Kari K. Kalliokoski, Jaakko Kaprio, Juhani Knuuti, Tuula Janatuinen, Tapani Rönnemaa, Jukka Kapanen, Olli J. Heinonen, Pirjo Nuutila
Publikováno v:
Journal of Applied Physiology. 101:1303-1311
We investigated heredity-independent effects of increased physical activity and aerobic fitness on skeletal muscle free fatty acid (FFA) uptake, perfusion, and their heterogeneity at rest and during exercise. Also, the relationship between local skel
Autor:
Terho Lehtimäki, Reijo Laaksonen, Tuula Janatuinen, Juhani Knuuti, Pirjo Nuutila, Riikka Rontu, Hanna Laine, Yue-Mei Fan, Olli T. Raitakari, Risto Vesalainen
Publikováno v:
Atherosclerosis. 188:391-397
Background The hepatic lipase (HL) gene C-480T promoter polymorphism affects gene transcription and enzyme activity and leads to CC, CT, and TT genotypes. Recently, HL expression was detected in macrophages. It has been postulated that HL might have
Autor:
Hannu Päivä, Riikka Rontu, Tuula Janatuinen, Reijo Laaksonen, Terho Lehtimäki, Juhani Knuuti, Jussi Matinheikki, Dieter Lütjohann, Karin M. Thelen, Klaus von Bergmann, Risto Vesalainen
Publikováno v:
Atherosclerosis. 185:206-209
Sterol regulatory element binding proteins-1 and -2 (SREBPs) are transcription factors controlling lipid homeostasis in human cells. The G-allele carriers of the SREBF-1 gene C-G polymorphism in exon 18c and coding for glycine at the protein level (G
Autor:
Pirjo Nuutila, Tuula Janatuinen, Jan Sundell, Ilkka Kantola, Juhani Knuuti, Kari K. Kalliokoski, Maila Penttinen, Jorma Viikari, Jarna C. Hannukainen, Riikka Kalliokoski, Olli T. Raitakari, Erik Engblom
Publikováno v:
Journal of Inherited Metabolic Disease. 29:112-118
Fabry disease (McKusick 301500) is an X-linked lysosomal storage disorder secondary to deficient alpha-galactosidase A activity which leads to the widespread accumulation of globotriaosylceramide (Gb(3)) and related glycosphingolipids, especially in
Autor:
Juhani Knuuti, Tuula Janatuinen, Reijo Laaksonen, Klaus von Bergmann, Risto Vesalainen, Karin M. Thelen, Dieter Lütjohann, Terho Lehtimäki
Publikováno v:
European Journal of Clinical Pharmacology. 62:9-14
The HMG-CoA reductase inhibitors, or statins, are well established in the prevention and treatment of coronary artery disease, mainly by lowering low-density lipoprotein (LDL) cholesterol levels. These compounds are structurally similar, but differ i
Autor:
Juhani Knuuti, Tapio Viljanen, Kirsti Hällsten, Risto Huupponen, Peter Lönnroth, Tapani Rönnemaa, Fredrik Lönnqvist, Patricia Iozzo, Kirsi A. Virtanen, Ele Ferrannini, Riitta Parkkola, Tuula Janatuinen, Pirjo Nuutila
Publikováno v:
Diabetes. 54:2720-2726
To evaluate the relative impact of abdominal obesity and newly diagnosed type 2 diabetes on insulin action in skeletal muscle and fat tissue, we studied 61 men with (n = 31) or without (n = 30) diabetes, subgrouped into abdominally obese or nonobese