Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Tuula, Pirttilä"'
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 858-870 (2005)
Chronic inflammation is known to play an important role in the heterogeneous pathogenesis of Alzheimer's disease (AD). Activated astrocytes expressing glial fibrillary acidic protein (GFAP) are closely associated with AD pathology, such as tangles, n
Externí odkaz:
https://doaj.org/article/1221fbdf843c498a85a83bb5cacf7587
The intracytoplasmic aggregation of alpha-synuclein (alphaS) protein is a common denominator for a group of neurodegenerative disorders currently known as synucleinopathies. It is generally assumed that the incorporation of alphaS protein into compac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a5b82f083c0b62a534149e4bb48dac
https://ora.ox.ac.uk/objects/uuid:e78ef162-f4a3-4779-bfd0-85381fc55346
https://ora.ox.ac.uk/objects/uuid:e78ef162-f4a3-4779-bfd0-85381fc55346
Autor:
Hilkka Soininen, Tuula Pirttilä, Päivi Hartikainen, Tero Tapiola, Laura Parkkinen, Sanna-Kaisa Herukka, Irina Alafuzoff
Background: There is a clear need to develop an objective diagnostic test for Alzheimer disease (AD). Changes in the levels of cerebrospinal fluid (CSF) tau protein and β-amyloid 42 (Aβ42) peptide in patients with AD have been well documented, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611436df7661e4f16893f827a808f8d2
https://ora.ox.ac.uk/objects/uuid:a6f5647d-8c6f-4e8b-9705-803a615e88b2
https://ora.ox.ac.uk/objects/uuid:a6f5647d-8c6f-4e8b-9705-803a615e88b2
Autor:
H. Soininen, Tuula Pirttilä, M Sotaniemi, Ilona Hallikainen, Laura Hokkanen, Veijo Pulliainen, T. Hänninen
Publikováno v:
Acta Neurologica Scandinavica. 125:16-23
Sotaniemi M, Pulliainen V, Hokkanen L, Pirttila T, Hallikainen I, Soininen H, Hanninen T. CERAD-neuropsychological battery in screening mild Alzheimer’s disease. Acta Neurol Scand: 2012: 125: 16–23. © 2011 John Wiley & Sons A/S. Objectives – T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e447d3beae81ae76b180fce52cdc14
https://doi.org/10.1111/j.1600-0404.2010.01459.x
https://doi.org/10.1111/j.1600-0404.2010.01459.x
Autor:
Tarja Välimäki, Juhani Sivenius, Sirpa Hartikainen, Jaana Suhonen, Hilkka Soininen, Kristiina Karttunen, Asta Hiltunen, Pertti Karppi, Tuula Pirttilä, Janne Martikainen, Hannu Valtonen, Matti Vanhanen
Publikováno v:
International Journal of Geriatric Psychiatry. 26:473-482
Background: Neuropsychiatric symptoms (NPS) are common manifestations of Alzheimer’ s disease (AD). Objective: To examine the prevalence and significance of NPS in very mild and mild AD patients with emphasis on their influence on the well-being of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45f1e953c5c0d6adaf40cef7b3ad481
https://doi.org/10.1002/gps.2550
https://doi.org/10.1002/gps.2550
Autor:
Jaakko Rinne, Sannakaisa Vainikka, Anne M. Koivisto, Mikael von und zu Fraunberg, Juuso N. Tamminen, Okko T. Pyykkö, Jaana Rummukainen, Juha E. Jääskeläinen, Sakari Savolainen, Tuula Pirttilä, Tomi Tillgren, Hilkka Soininen, Juhani A A Mölsä, Ville Leinonen, Irina Alafuzoff
Publikováno v:
Annals of Neurology. 68:446-453
Objective: Amyloid-beta(A beta) aggregates are presumed to be found in the brain at an early stage of Alzheimer's disease (AD) but have seldom been assessed by brain biopsy during life in often elderly patients. Methods: Between 1991 and 2006 we eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eeb5b5e0a4e49bcb822a4e4f8e50094
https://doi.org/10.1002/ana.22100
https://doi.org/10.1002/ana.22100
Autor:
Teppo Varilo, Chris H. Polman, Maria-Liisa Sumelahti, Stacey Gabriel, Anna-Maija Kristiina Sulonen, Arpo Aromaa, David A. Hafler, Pentti J. Tienari, Inger-Lise Mero, Eveliina Jakkula, Stephen L. Hauser, Aarno Palotie, Daniel B. Mirel, Mauri Reunanen, Leena Peltonen, Ludwig Kappos, Shaun Purcell, Annette Bang Oturai, Anu Kemppinen, Helle Bach Søndergaard, Irina Elovaara, Hanne F. Harbo, Philip L. De Jager, Tuula Pirttilä, Keijo Koivisto, Virpi Leppa, Janna Saarela, Mark J. Daly, Suvi P. Kallio
Publikováno v:
American journal of human genetics, 86(2), 285-291. Cell Press
Jakkula, E, Leppa, V, Sulonen, A M, Varilo, T, Kallio, S, Kemppinen, A, Purcell, S, Koivisto, K, Tienari, P, Sumelahti, M L, Elovaara, I, Pirttila, T, Reunanen, M, Aromaa, A, Oturai, A B, Sondergaard, H B, Harbo, H F, Mero, I L, Gabriel, S B, Mirel, D B, Hauser, S L, Kappos, L, Polman, C H, de Jager, P L, Hafler, D A, Daly, M J, Palotie, A, Saarela, J & Peltonen, L 2010, ' Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene ', American journal of human genetics, vol. 86, no. 2, pp. 285-291 . https://doi.org/10.1016/j.ajhg.2010.01.017
Jakkula, E, Leppa, V, Sulonen, A M, Varilo, T, Kallio, S, Kemppinen, A, Purcell, S, Koivisto, K, Tienari, P, Sumelahti, M L, Elovaara, I, Pirttila, T, Reunanen, M, Aromaa, A, Oturai, A B, Sondergaard, H B, Harbo, H F, Mero, I L, Gabriel, S B, Mirel, D B, Hauser, S L, Kappos, L, Polman, C H, de Jager, P L, Hafler, D A, Daly, M J, Palotie, A, Saarela, J & Peltonen, L 2010, ' Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene ', American journal of human genetics, vol. 86, no. 2, pp. 285-291 . https://doi.org/10.1016/j.ajhg.2010.01.017
Genetic risk for multiple sclerosis (MS) is thought to involve both common and rare risk alleles. Recent GWAS and subsequent meta-analysis have established the critical role of the HLA locus and identified new common variants associated to MS. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1ddbb7bb17173c8b5e8e0d4ba16514
https://doi.org/10.1016/j.ajhg.2010.01.017
https://doi.org/10.1016/j.ajhg.2010.01.017
Autor:
Bengt Winblad, Jean-Pierre Michel, Vasileios Papaliagkas, George Anogianakis, Bruno Vellas, Lutz Frölich, Frans R.J. Verhey, Pieter Jelle Visser, H. Soininen, Murat Emre, Tuula Pirttilä, Roberto Bernabei, Tomasz Sobów, Magda Tsolaki, M.G.M. Olde Rikkert
Publikováno v:
Journal of Nutrition, Health & Aging, 14, 2, pp. 131-5
Journal of Nutrition Health & Aging, 14(2), 131-135. Springer
Journal of Nutrition, Health & Aging, 14, 131-5
Tsolaki, M, Papaliagkas, V, Anogianakis, G, Bernabei, R, Emre, M, Frolich, L, Visser, P J, Michel, J P, Pirttila, T, Rikkert, M O, Soininen, H, Sobow, T, Vellas, B, Verhey, F & Winblad, B 2010, ' Consensus Statement on Dementia Education and Training in Europe ', Journal of Nutrition Health and Aging, vol. 14, no. 2, pp. 131-135 . https://doi.org/10.1007/s12603-009-0238-z
Journal of Nutrition Health and Aging, 14(2), 131-135. Springer Paris
Journal of Nutrition, Health and Aging, Vol. 14, No 2 (2010) pp. 131-135
Journal of Nutrition Health & Aging, 14(2), 131-135. Springer
Journal of Nutrition, Health & Aging, 14, 131-5
Tsolaki, M, Papaliagkas, V, Anogianakis, G, Bernabei, R, Emre, M, Frolich, L, Visser, P J, Michel, J P, Pirttila, T, Rikkert, M O, Soininen, H, Sobow, T, Vellas, B, Verhey, F & Winblad, B 2010, ' Consensus Statement on Dementia Education and Training in Europe ', Journal of Nutrition Health and Aging, vol. 14, no. 2, pp. 131-135 . https://doi.org/10.1007/s12603-009-0238-z
Journal of Nutrition Health and Aging, 14(2), 131-135. Springer Paris
Journal of Nutrition, Health and Aging, Vol. 14, No 2 (2010) pp. 131-135
Item does not contain fulltext OBJECTIVES: The aim of the current statement is to agree on: (1) what is the current situation with education and training on dementia in Europe; (2) what are the minimum educational requirements for professionals (neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7f2c6aac349c7220a6c607790023bd
https://doi.org/10.1007/s12603-009-0238-z
https://doi.org/10.1007/s12603-009-0238-z
Autor:
Auli Verkkoniemi, Leena Niinistö, Raimo Sulkava, Sari Rastas, Esko Länsimies, Kimmo Mattila, Tuula Pirttilä, Kati Juva
Publikováno v:
Neurobiology of Aging. 31:1-7
The aim of this study was to evaluate the association between dementia and common vascular risk factors including blood pressure, blood lipids, homocysteine and diabetes mellitus in a population of very old people. This study is a 9-year follow-up pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af182c9204ced87121e8df5d79fc121
https://doi.org/10.1016/j.neurobiolaging.2008.02.020
https://doi.org/10.1016/j.neurobiolaging.2008.02.020
Publikováno v:
Aging & Mental Health. 13:799-807
The main objective is to examine the sense of coherence (SOC) of spouse caregivers. The aim was further investigate the association of SOC, health-related quality of life (HRQoL), depressive symptoms, distress and how severity of Alzheimer's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab7140d5128df5176bddeeeb8a951aa
https://doi.org/10.1080/13607860903046487
https://doi.org/10.1080/13607860903046487