Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Tuula, Pelkonen"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Although rarely reported, bilateral loss of vision is a severe complication of childhood bacterial meningitis. We assessed its frequency in five prospective treatment trials performed in Europe, Latin America, and Angola in 1984–2017. Cour
Externí odkaz:
https://doaj.org/article/5dc7a0af22ac4bf38eba93f601fb4d00
Autor:
Okko Savonius, Cintia F. de Souza, Cláudia Fançony, Manuel Leite Cruzeiro, Miguel Brito, Tuula Pelkonen
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background In malaria-endemic areas, children presenting to hospitals with a decreased level of consciousness remain a diagnostic dilemma. The definition of cerebral malaria in a comatose child demands exclusion of other possible reasons, wh
Externí odkaz:
https://doaj.org/article/b9a5def5986a46338b66c96213f92a26
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Our objective was to explore the importance of underweight on the course of childhood bacterial meningitis (BM) at different study sites, because prior studies showed discrepant results. Using directly comparable, prospective data from three
Externí odkaz:
https://doaj.org/article/c745c6e425b04eba8327b3a87c8bc1ce
Autor:
Hamada S Badr, PhD, Josh M Colston, PhD, Nhat-Lan H Nguyen, BA, Yen Ting Chen, MD, Eleanor Burnett, MPH, Syed Asad Ali, MPH, Ajit Rayamajhi, MD, Syed M Satter, MPH, Nguyen Van Trang, PhD, Daniel Eibach, PD, Ralf Krumkamp, DrPH, Jürgen May, MD, Ayola Akim Adegnika, PhD, Gédéon Prince Manouana, PhD, Peter Gottfried Kremsner, MD, Roma Chilengi, MSc, Luiza Hatyoka, PhD, Amanda K Debes, PhD, Jerome Ateudjieu, PhD, Abu S G Faruque, MPH, M Jahangir Hossain, MSc, Suman Kanungo, PhD, Karen L Kotloff, MD, Inácio Mandomando, PhD, M Imran Nisar, PhD, Richard Omore, PhD, Samba O Sow, MSc, Anita K M Zaidi, SM, Nathalie Lambrecht, PhD, Bright Adu, PhD, Nicola Page, MPH, James A Platts-Mills, MD, Cesar Mavacala Freitas, MD, Tuula Pelkonen, PhD, Per Ashorn, PhD, Kenneth Maleta, PhD, Tahmeed Ahmed, PhD, Pascal Bessong, PhD, Zulfiqar A Bhutta, PhD, Carl Mason, MD, Estomih Mduma, PhD, Maribel P Olortegui, MPH, Pablo Peñataro Yori, MPH, Aldo A M Lima, PhD, Gagandeep Kang, PhD, Jean Humphrey, ScD, Robert Ntozini, MPH, Andrew J Prendergast, DPhil, Kazuhisa Okada, PhD, Warawan Wongboot, PhD, Nina Langeland, PhD, Sabrina J Moyo, PhD, James Gaensbauer, MD, Mario Melgar, MD, Matthew Freeman, PhD, Anna N Chard, MPH, Vonethalom Thongpaseuth, MD, Eric Houpt, MD, Benjamin F Zaitchik, PhD, Margaret N Kosek, MD
Publikováno v:
The Lancet Global Health, Vol 11, Iss 3, Pp e373-e384 (2023)
Summary: Background: Diarrhoeal disease is a leading cause of childhood illness and death globally, and Shigella is a major aetiological contributor for which a vaccine might soon be available. The primary objective of this study was to model the spa
Externí odkaz:
https://doaj.org/article/bf7cee71ef0a40cfb55dc0350ac997ee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Our objective was to quantify the differences in the outcomes from childhood bacterial meningitis (BM) and to describe the factors associated with them in different parts of the world. This study is a secondary analysis of prospectively coll
Externí odkaz:
https://doaj.org/article/460814bdad39410ea087b7d47e728f7a
Publikováno v:
International Journal of Infectious Diseases, Vol 106, Iss , Pp 223-227 (2021)
Background: Yearly, about two million infants die during the first 28 days of life. Most of these deaths occur in sub-Saharan Africa and a third of those are caused by severe infections. The early identification of infants at risk of death is importa
Externí odkaz:
https://doaj.org/article/b4fd099953cc42b79e882e5699b4a5c2
Autor:
Tuula Pelkonen, Suvi Urtti, Elizabete dos Anjos, Ondina Cardoso, Linda de Gouveia, Irmeli Roine, Heikki Peltola, Anne von Gottberg, Moe H. Kyaw
Publikováno v:
International Journal of Infectious Diseases, Vol 97, Iss , Pp 251-257 (2020)
Background: Despite effective antibiotics and vaccines, bacterial meningitis (BM) remains one of the leading causes of morbidity and mortality in young infants worldwide. Data from Africa on the aetiology and antibiotic susceptibility are scarce. Obj
Externí odkaz:
https://doaj.org/article/9d79753dda394552852e9a908261ff5c
Publikováno v:
BMJ Open, Vol 12, Iss 3 (2022)
Objectives To describe the prevalence and severity of anaemia and to examine its associations with outcome in children with bacterial meningitis (BM).Design Secondary analysis of descriptive data from five randomised BM treatment trials.Setting Hospi
Externí odkaz:
https://doaj.org/article/7a5591bc82384c5c8220d400475e8f3a
Autor:
Emilie Rugemalira, Irmeli Roine, Julia Kuligowski, Ángel Sánchez-Illana, José David Piñeiro-Ramos, Sture Andersson, Manuel Leite Cruzeiro, Máximo Vento, Tuula Pelkonen
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 621 (2023)
Neuronal damage in bacterial meningitis (BM) partly stems from the host´s inflammatory response and induced oxidative stress (OS). We studied the association of cerebrospinal fluid (CSF) biomarkers indicating oxidative damage to proteins with course
Externí odkaz:
https://doaj.org/article/8e55282493254ea3968cbe1bf7c18824
Autor:
Josh M. Colston, Benjamin F. Zaitchik, Hamada S. Badr, Eleanor Burnett, Syed Asad Ali, Ajit Rayamajhi, Syed M. Satter, Daniel Eibach, Ralf Krumkamp, Jürgen May, Roma Chilengi, Leigh M. Howard, Samba O. Sow, M. Jahangir Hossain, Debasish Saha, M. Imran Nisar, Anita K. M. Zaidi, Suman Kanungo, Inácio Mandomando, Abu S. G. Faruque, Karen L. Kotloff, Myron M. Levine, Robert F. Breiman, Richard Omore, Nicola Page, James A. Platts‐Mills, Ulla Ashorn, Yue‐Mei Fan, Prakash Sunder Shrestha, Tahmeed Ahmed, Estomih Mduma, Pablo Penatero Yori, Zulfiqar Bhutta, Pascal Bessong, Maribel P. Olortegui, Aldo A. M. Lima, Gagandeep Kang, Jean Humphrey, Andrew J. Prendergast, Robert Ntozini, Kazuhisa Okada, Warawan Wongboot, James Gaensbauer, Mario T. Melgar, Tuula Pelkonen, Cesar Mavacala Freitas, Margaret N. Kosek
Publikováno v:
GeoHealth, Vol 6, Iss 1, Pp n/a-n/a (2022)
Abstract Diarrheal disease, still a major cause of childhood illness, is caused by numerous, diverse infectious microorganisms, which are differentially sensitive to environmental conditions. Enteropathogen‐specific impacts of climate remain undere
Externí odkaz:
https://doaj.org/article/03f18da390284377aac41ad948842268