Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

Autor: Jin, X., Bauer, D. E., Tuttleton, S. E., Lewin, S., Gettie, A., Blanchard, J., Irwin, C. E., Safrit, J. T., Mittler, J., Weinberger, L., Kostrikis, Leontios G., Zhang, L., Perelson, A. S., Ho, David D.

Publikováno v: Journal of Experimental Medicine
J.Exp.Med.
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 189, iss 6

To determine the role of CD8+ T cells in controlling simian immunodeficiency virus (SIV) replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 monoclonal antibody, OKT8F. There was on average a 99.9% reductio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a20753deea88141bdbf167b08183ffd
https://doi.org/10.1084/jem.189.6.991