Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tushar H More"'
Autor:
Amanda D. Vasconcelos, Carlos M. Donado-Pestana, Tushar H. More, Graziela B. S. Duarte, Stephany G. Duarte, Caroline G. Dias, Larissa Rodrigues, Guilherme N. Hernandez, Ricardo Fock, Karsten Hiller, Jarlei Fiamoncini
Publikováno v:
Food Production, Processing and Nutrition, Vol 6, Iss 1, Pp 1-12 (2024)
Abstract The hormonal decline during menopause increases women's risk of chronic diseases. D-limonene, a monoterpene found in the human diet, possesses biological properties related to hypolipemic, antioxidant, anti-inflammatory, and gut microbiota-m
Externí odkaz:
https://doaj.org/article/98cc37d687ad4b6b8c93eae4ce0e3c18
Autor:
Tushar H. More, Karsten Hiller, Martin Seifert, Thomas Illig, Rudi Schmidt, Raphael Gronauer, Thomas von Hahn, Hauke Weilert, Axel Stang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundCachexia is a body wasting syndrome that significantly affects well-being and prognosis of cancer patients, without effective treatment. Serum metabolites take part in pathophysiological processes of cancer cachexia, but apart from altered
Externí odkaz:
https://doaj.org/article/877b087badc74524b315595bfa9f72aa
Autor:
Liliana Francois, Pavle Boskovic, Julian Knerr, Wei He, Gianluca Sigismondo, Carsten Schwan, Tushar H. More, Magdalena Schlotter, Myra E. Conway, Jeroen Krijgsveld, Karsten Hiller, Robert Grosse, Peter Lichter, Bernhard Radlwimmer
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112217- (2023)
Externí odkaz:
https://doaj.org/article/229f5b8a382341f4a205339cc231a4fe
Autor:
Leticia Soriano-Baguet, Melanie Grusdat, Henry Kurniawan, Mohaned Benzarti, Carole Binsfeld, Anouk Ewen, Joseph Longworth, Lynn Bonetti, Luana Guerra, Davide G. Franchina, Takumi Kobayashi, Veronika Horkova, Charlène Verschueren, Sergio Helgueta, Deborah Gérard, Tushar H. More, Antonia Henne, Catherine Dostert, Sophie Farinelle, Antoine Lesur, Jean-Jacques Gérardy, Christian Jäger, Michel Mittelbronn, Lasse Sinkkonen, Karsten Hiller, Johannes Meiser, Dirk Brenner
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112153- (2023)
Summary: Pyruvate dehydrogenase (PDH) is the central enzyme connecting glycolysis and the tricarboxylic acid (TCA) cycle. The importance of PDH function in T helper 17 (Th17) cells still remains to be studied. Here, we show that PDH is essential for
Externí odkaz:
https://doaj.org/article/4c586aa5408c4295a1eead933ab65a54
Autor:
Antonia Henne, Anna Vigh, Andre Märtens, Yannic Nonnenmacher, Melanie Ohm, Shirin Hosseini, Tushar H. More, Mario A. Lauterbach, Hendrikus Garritsen, Martin Korte, Wei He, Karsten Hiller
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
A reliable method for metabolite extraction is central to mass spectrometry-based metabolomics. However, existing methods are lengthy, mostly due to the step of scraping cells from cell culture vessels, which restricts metabolomics in broader applica
Externí odkaz:
https://doaj.org/article/26d5326798a54162a402ca3cc2ff8f03
Autor:
Tushar H. More, Bahareh Mozafari, Andre Märtens, Christian Herr, Philipp M. Lepper, Guy Danziger, Thomas Volk, Sabrina Hoersch, Marcin Krawczyk, Katharina Guenther, Karsten Hiller, Robert Bals
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1058 (2022)
Pneumonia is a common cause of morbidity and mortality and is most often caused by bacterial pathogens. COVID-19 is characterized by lung infection with potential progressive organ failure. The systemic consequences of both disease on the systemic bl
Externí odkaz:
https://doaj.org/article/5a85c475588346eaadc30512bfb9448f
Autor:
Arshad Rizvi, Arvind Shankar, Ankita Chatterjee, Tushar H. More, Tungadri Bose, Anirban Dutta, Kannan Balakrishnan, Lavanya Madugulla, Srikanth Rapole, Sharmila S. Mande, Sharmistha Banerjee, Shekhar C. Mande
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Metabolic adaptation of Mycobacterium tuberculosis (M. tuberculosis) to microbicidal intracellular environment of host macrophages is fundamental to its pathogenicity. However, an in-depth understanding of metabolic adjustments through key reaction p
Externí odkaz:
https://doaj.org/article/02529eb3495744e8acfc211eef82c069
Autor:
Khushman Taunk, Anupama Mane, Ravindra Taware, Tushar H. More, Srikanth Rapole, Muralidhararao Bagadi
Publikováno v:
RSC Advances. 11:397-407
The need of identifying alternative therapeutic targets for invasive ductal carcinoma (IDC) of the breast with high specificity and sensitivity for effective therapeutic intervention is crucial for lowering the risk of fatality. Lipidomics has emerge
Autor:
Tushar H More, Karsten Hiller
Publikováno v:
Current Opinion in Biotechnology. 75:102711
Subcellular compartmentalization provides cells with tremendous advantages for the operation of cellular metabolism. Spatial separation of metabolism generates microenvironments with distinct concentrations of metabolites and cofactors allowing the c
Autor:
Liliana Francois, Pavle Boskovic, Julian Knerr, Wei He, Gianluca Sigismondo, Carsten Schwan, Tushar H. More, Magdalena Schlotter, Myra E. Conway, Jeroen Krijgsveld, Karsten Hiller, Robert Grosse, Peter Lichter, Bernhard Radlwimmer
Publikováno v:
Cell reports. 41(3)
The metabolic enzyme branched-chain amino acid transaminase 1 (BCAT1) drives cell proliferation in aggressive cancers such as glioblastoma. Here, we show that BCAT1 localizes to mitotic structures and has a non-metabolic function as a mitotic regulat