Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tushar G. Kokate"'
Publikováno v:
Neuropharmacology. 35:423-431
Ibogaine is an hallucinogenic indole alkaloid claimed to have anti-addictive properties. Although its mechanism of action is unknown, binding studies have indicated that the drug may interact with N-methyl-D-aspartate (NMDA) receptors. We further inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc37d946342ba20ca2018f2bad8cb2c7
https://doi.org/10.1016/0028-3908(96)84107-4
https://doi.org/10.1016/0028-3908(96)84107-4
Autor:
Tushar G. Kokate, Dung Q. Le, Michael A. Rogawski, Swaminathan Subramaniam, Lewis K. Pannell, Shunichi Yamaguchi, Duangchan Uyakul
Publikováno v:
Epilepsia. 36:566-571
Summary: ADCI (5-aminocarbonyl-10, 11-dihydro-5H-dibenzo[a, d] cyclohepten-5,10-imine), a low-affinity uncompetitive N-methyl-d-aspartate (NMDA) antagonist, is a broad-spectrum anticonvulsant with a favorable side-effect profile. In the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac19629e9f2e217e44e54d3c4270f0c
https://doi.org/10.1111/j.1528-1157.1995.tb02568.x
https://doi.org/10.1111/j.1528-1157.1995.tb02568.x
Autor:
Shun Ichi Yamaguchi, Tushar G. Kokate, Jose Llamas, R.Duncan Kirkby, Michael A. Rogawski, Kyungho N. Juhng
Publikováno v:
Brain research. 831(1-2)
Pregnenolone sulfate (PS) is an endogenous neurosteroid known to antagonize GABAA receptor-mediated inhibitory responses and potentiate NMDA receptor-mediated excitatory responses in vitro. To assess the actions of the steroid as a modulator of seizu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdc2df096fd1699c0e1782edd3e4cff
https://pubmed.ncbi.nlm.nih.gov/10411990
https://pubmed.ncbi.nlm.nih.gov/10411990
Autor:
Shun Ichi Yamaguchi, Mordecai P. Blaustein, Michael A. Rogawski, R. S. Rogowski, Tushar G. Kokate, B. Y. Kim, K. N. Juhng
Publikováno v:
Epilepsy research. 34(2-3)
The scorpion venom peptide toxins tityustoxin-K(alpha) (TsTx-K(alpha)) and pandinustoxin-K(alpha) (PiTx-K(alpha)) are novel, highly potent and selective blockers of voltage-activated K+ channels. PiTx-K(alpha) preferentially blocks rapidly inactivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebac8acadd93dc7282292ad6cdb8e315
https://pubmed.ncbi.nlm.nih.gov/10210033
https://pubmed.ncbi.nlm.nih.gov/10210033
Further studies on anti- and proconvulsant effects of inhibitors of nitric oxide synthase in rodents
Publikováno v:
European journal of pharmacology. 344(1)
We confirmed that the effects of inhibitors of nitric oxide (NO) synthase, such as Nomega-nitro-L-arginine methyl ester and Nomega-nitro-L-arginine, differ depending on several experimental factors. Both compounds but not their less active enantiomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c127ee0cd96a77e98d8be544c401dc5a
https://pubmed.ncbi.nlm.nih.gov/9570442
https://pubmed.ncbi.nlm.nih.gov/9570442
Publikováno v:
Neuropharmacology. 35(8)
Several structurally related metabolites of progesterone (3 alpha-hydroxy pregnane-20-ones) and deoxycorticosterone (3 alpha-hydroxy pregnane-21-diol-20-ones) and their 3 beta-epimers were evaluated for protective activity against pilocarpine-, kaini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba5bd1c522890ba52e71c624ca10a61
https://pubmed.ncbi.nlm.nih.gov/9121607
https://pubmed.ncbi.nlm.nih.gov/9121607
Autor:
Tushar G. Kokate, George B. Frank
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 67:435-441
The effect of several opioid drugs was tested on the K+ contractures in frog's skeletal muscle. These contractures are produced by the entrance of extracellular Ca2+ ions via the voltage-dependent, slow Ca2+ channels located in the T tubules. Morphin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5813b70fd563125973ddd5c2563a32
https://doi.org/10.1139/y89-070
https://doi.org/10.1139/y89-070