Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations.

Autor: Dulla K; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Slijkerman R; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., van Diepen HC; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Albert S; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Dona M; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Beumer W; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Turunen JJ; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Chan HL; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Schulkens IA; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Vorthoren L; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., den Besten C; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Buil L; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Schmidt I; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Miao J; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Venselaar H; Center for Molecular and Biomolecular Informatics, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Zang J; University of Zürich, Institute of Molecular Life Sciences, 8057 Zürich, Switzerland., Neuhauss SCF; University of Zürich, Institute of Molecular Life Sciences, 8057 Zürich, Switzerland., Peters T; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Broekman S; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Pennings R; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Kremer H; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Platenburg G; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands., Adamson P; ProQR Therapeutics, Zernikedreef 9, 2333 CK Leiden, the Netherlands; UCL, Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK., de Vrieze E; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., van Wijk E; Department of Otorhinolaryngology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands. Electronic address: erwin.vanwyk@radboudumc.nl.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Aug 04; Vol. 29 (8), pp. 2441-2455. Date of Electronic Publication: 2021 Apr 23.

Probabilistic assessment of the impact of bottom sediment on doses to humans from a groundwater-mediated radionuclide release in a farm-lake scenario.

Autor: Pohjola JK; Tampere University, Pohjoisranta 11 A, FI-28100, Pori, Finland., Turunen JJ, Lipping T, Ikonen ATK

Publikováno v: Journal of radiological protection : official journal of the Society for Radiological Protection [J Radiol Prot] 2019 Jun; Vol. 39 (2), pp. 564-578. Date of Electronic Publication: 2019 Mar 26.

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.

Autor: Sork H; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Nordin JZ; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Turunen JJ; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Wiklander OP; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Bestas B; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Zaghloul EM; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden.; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, El-Khartoum square, Alexandria, Egypt., Margus H; Department of Developmental Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Padari K; Department of Developmental Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Duru AD; Department of Medicine, Center for Infectious Medicine, Novum, Karolinska Institutet, Huddinge, Sweden.; Cell Therapies Institute, Nova Southeastern University, Fort Lauderdale, Florida, USA., Corso G; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Bost J; Department of Biomedical Engineering, College of Engineering and Technology, Wentworth Institute of Technology, Boston, Massachusetts, USA., Vader P; Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands., Pooga M; Department of Developmental Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Smith CE; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden., Wood MJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Schiffelers RM; Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands., Hällbrink M; Department of Neurochemistry, Stockholm University, Stockholm, Sweden., Andaloussi SE; Department of Laboratory Medicine, Clinical Research Center, Novum, Karolinska Institutet, Huddinge, Sweden.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2016 Mar 08; Vol. 5, pp. e290. Date of Electronic Publication: 2016 Mar 08.

Agammaglobulinemia: causative mutations and their implications for novel therapies.

Autor: Berglöf A; Department of Laboratory Medicine, Karolinska Institutet, Hälsovägen 7, SE-14186 Huddinge, Sweden., Turunen JJ, Gissberg O, Bestas B, Blomberg KE, Smith CI

Publikováno v: Expert review of clinical immunology [Expert Rev Clin Immunol] 2013 Dec; Vol. 9 (12), pp. 1205-21.

The significant other: splicing by the minor spliceosome.

Autor: Turunen JJ; Institute of Biotechnology, University of Helsinki, Helsinki, Finland., Niemelä EH, Verma B, Frilander MJ

Publikováno v: Wiley interdisciplinary reviews. RNA [Wiley Interdiscip Rev RNA] 2013 Jan-Feb; Vol. 4 (1), pp. 61-76. Date of Electronic Publication: 2012 Oct 16.