Výsledky vyhledávání - "Turner Darryl G"

Akademický článek

Production of eosinophil chemoattractant activity by ovine gastrointestinal nematodes

Autor: Wildblood, Louise A., Kerr, Karen, Clark, Douglas A.S., Cameron, Alisdair, Turner, Darryl G., Jones, Douglas G. ^*

Publikováno v: In Veterinary Immunology and Immunopathology 2005 107(1):57-65

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Akademický článek

TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis

Autor: Mellanby Richard J, Cambrook Helen, Turner Darryl G, O’Connor Richard A, Leech Melanie D, Kurschus Florian C, MacDonald Andrew S, Arnold Bernd, Anderton Stephen M

Publikováno v: Journal of Neuroinflammation, Vol 9, Iss 1, p 248 (2012)

Abstract Background Experimental autoimmune encephalomyelitis (EAE) depends on the initial activation of CD4+ T cells responsive to myelin autoantigens. The key antigen presenting cell (APC) population that drives the activation of naïve T cells mos

Externí odkaz: https://doaj.org/article/7365feb4aef04f5baabaa9f5da48a34c

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Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors

Autor: Colbeck, Emily J, Hindley, James P, Smart, Kathryn, Jones, Emma, Bloom, Anja, Bridgeman, Hayley, McPherson, Rhoanne C, Turner, Darryl G, Ladell, Kristin, Price, David A, O'Connor, Richard A, Anderton, Stephen M, Godkin, Andrew J, Gallimore, Awen M

Publikováno v: Colbeck, E J, Hindley, J P, Smart, K, Jones, E, Bloom, A, Bridgeman, H, McPherson, R C, Turner, D G, Ladell, K, Price, D A, O'Connor, R A, Anderton, S M, Godkin, A J & Gallimore, A M 2015, ' Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors ', Oncotarget, vol. 6, no. 28, pp. 24649-59 . https://doi.org/10.18632/oncotarget.5584

Foxp3+ regulatory T cells (Tregs) are often highly enriched within the tumor-infiltrating T cell pool. Using a well-characterised model of carcinogen-induced fibrosarcomas we show that the enriched tumor-infiltrating Treg population comprises largely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6610019ae46174a00831709867bcd476

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Exposure to inflammatory cytokines selectively limits GM-CSF production by induced T regulatory cells

Autor: Reynolds, Ben C., Turner, Darryl G., McPherson, Rhoanne C., Prendergast, Catriona T., Phelps, Richard G., Turner, Neil A., O'Connor, Richard A., Anderton, Stephen M.

Publikováno v: Reynolds, B C, Turner, D G, McPherson, R C, Prendergast, C T, Phelps, R G, Turner, N A, O'Connor, R A & Anderton, S M 2014, ' Exposure to inflammatory cytokines selectively limits GM-CSF production by induced T regulatory cells ', European Journal of Immunology, vol. 44, no. 11, pp. 3342–3352 . https://doi.org/10.1002/eji.201444687

Interest in manipulating the immunosuppressive powers of Foxp3-expressing T regulatory (Treg) cells as an immunotherapy has been tempered by their reported ability to produce pro-inflammatory cytokines when manipulated in vitro, or in vivo. Understan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ed4b2d5f940c6ab6c696f4b4feaa7b1f
https://eprints.gla.ac.uk/109287/1/109287.pdf

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