Basal-epithelial subpopulations underlie and predict chemotherapy resistance in triple-negative breast cancer.

Autor: Inayatullah M; Institute for Molecular Medicine, University of Southern Denmark, Odense M, Denmark., Mahesh A; Institute for Molecular Medicine, University of Southern Denmark, Odense M, Denmark., Turnbull AK; Edinburgh Breast Cancer Now Research Group, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Dixon JM; Edinburgh Breast Cancer Now Research Group, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Natrajan R; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK., Tiwari VK; Institute for Molecular Medicine, University of Southern Denmark, Odense M, Denmark. tiwari@health.sdu.dk.; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queens University Belfast, Belfast, BT9 7BL, UK. tiwari@health.sdu.dk.; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, BT9 7AE, UK. tiwari@health.sdu.dk.; Danish Institute for Advanced Study (DIAS), Odense M, Denmark. tiwari@health.sdu.dk.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. tiwari@health.sdu.dk.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2024 Apr; Vol. 16 (4), pp. 823-853. Date of Electronic Publication: 2024 Mar 13.

Neoadjuvant endocrine therapy in postmenopausal women with HR+/HER2- breast cancer.

Autor: Martínez-Pérez C; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Edinburgh Breast Cancer Now Research Team, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Turnbull AK; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Edinburgh Breast Cancer Now Research Team, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Kay C; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Edinburgh Breast Cancer Now Research Team, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Dixon JM; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Edinburgh Breast Cancer Now Research Team, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Edinburgh Breast Unit, Western General Hospital, Edinburgh, Scotland.

Publikováno v: Expert review of anticancer therapy [Expert Rev Anticancer Ther] 2023 Jan; Vol. 23 (1), pp. 67-86. Date of Electronic Publication: 2023 Jan 19.

Characterisation of the Stromal Microenvironment in Lobular Breast Cancer.

Autor: Gómez-Cuadrado L; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK., Bullock E; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK., Mabruk Z; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK., Zhao H; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada., Souleimanova M; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada., Noer PR; Department of Molecular Biology and Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark., Turnbull AK; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK., Oxvig C; Department of Molecular Biology and Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark., Bertos N; Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada., Byron A; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK., Dixon JM; Edinburgh Breast Unit, University of Edinburgh, Edinburgh EH4 2XU, UK., Park M; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada., Haider S; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Natrajan R; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Sims AH; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK., Brunton VG; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK.

Publikováno v: Cancers [Cancers (Basel)] 2022 Feb 11; Vol. 14 (4). Date of Electronic Publication: 2022 Feb 11.

A Novel Approach for the Discovery of Biomarkers of Radiotherapy Response in Breast Cancer.

Autor: Meehan J; Translational Oncology Research Group, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Gray M; The Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh, Midlothian EH25 9RG, UK., Martínez-Pérez C; Translational Oncology Research Group, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.; Breast Cancer Now Edinburgh Research Team, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Kay C; Translational Oncology Research Group, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.; Breast Cancer Now Edinburgh Research Team, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Wills JC; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK.; Firefinch Software Ltd., Edinburgh EH12 9DQ, UK., Kunkler IH; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK., Dixon JM; Breast Cancer Now Edinburgh Research Team, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Turnbull AK; Translational Oncology Research Group, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.; Breast Cancer Now Edinburgh Research Team, Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.

Publikováno v: Journal of personalized medicine [J Pers Med] 2021 Aug 14; Vol. 11 (8). Date of Electronic Publication: 2021 Aug 14.

The Signal Transducer IL6ST (gp130) as a Predictive and Prognostic Biomarker in Breast Cancer.

Autor: Martínez-Pérez C; Breast Cancer Now Edinburgh Research Team, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Leung J; Breast Cancer Now Edinburgh Research Team, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Kay C; Breast Cancer Now Edinburgh Research Team, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Meehan J; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Gray M; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Dixon JM; Breast Cancer Now Edinburgh Research Team, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK., Turnbull AK; Breast Cancer Now Edinburgh Research Team, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.; Translational Oncology Research Group, MRC Institute of Genetics and Cancer, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XU, UK.

Publikováno v: Journal of personalized medicine [J Pers Med] 2021 Jun 29; Vol. 11 (7). Date of Electronic Publication: 2021 Jun 29.