Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies.

Autor: Chen BM; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan., Chen E; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan., Lin YC; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan., Tran TTM; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan., Turjeman K; Department of Biochemistry and Molecular Biology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel., Yang SH; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan., Cheng TL; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan., Barenholz Y; Department of Biochemistry and Molecular Biology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel., Roffler SR; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Publikováno v: ACS nano [ACS Nano] 2024 Aug 20; Vol. 18 (33), pp. 22122-22138. Date of Electronic Publication: 2024 Aug 09.

Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA-Lipid Complexes.

Autor: Szebeni J; Nanomedicine Research and Education Center, Department of Translational Medicine, Semmelweis University, Budapest 1089, Hungary.; Department of Nanobiotechnology and Regenerative Medicine, Faculty of Health Sciences, Miskolc University, Miskolc 2880, Hungary.; School of Chemical Engineering and Translational Nanobioscience Research Center, Sungkyunkwan University, Suwon 16419, Korea., Kiss B; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest 1094, Hungary.; Hungarian Centre of Excellence for Molecular Medicine (HCEMM), In Vivo Imaging Advanced Core Facility, Budapest 1094, Hungary.; ELKH-SE Biophysical Virology Research Group, Budapest 1094, Hungary., Bozó T; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest 1094, Hungary.; Hungarian Centre of Excellence for Molecular Medicine (HCEMM), In Vivo Imaging Advanced Core Facility, Budapest 1094, Hungary., Turjeman K; The Laboratory of Membrane and Liposome Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem 9112102, Israel., Levi-Kalisman Y; Institute of Life Sciences and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel., Barenholz Y; The Laboratory of Membrane and Liposome Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem 9112102, Israel., Kellermayer M; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest 1094, Hungary.; Hungarian Centre of Excellence for Molecular Medicine (HCEMM), In Vivo Imaging Advanced Core Facility, Budapest 1094, Hungary.; ELKH-SE Biophysical Virology Research Group, Budapest 1094, Hungary.

Publikováno v: ACS nano [ACS Nano] 2023 Jul 25; Vol. 17 (14), pp. 13147-13157. Date of Electronic Publication: 2023 Jul 07.

Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines.

Autor: Szebeni J; Nanomedicine Research and Education Center, Institute of Translational Medicine, Semmelweis University, Budapest, Hungary.; SeroScience LCC, Budapest, Hungary.; Department of Nanobiotechnology and Regenerative Medicine, Faculty of Health, Miskolc University, Miskolc, Hungary., Storm G; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, the Netherlands.; Department of Biomaterials Science and Technology, University of Twente, Enschede, the Netherlands.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ljubimova JY; Terasaki Institute for Biomedical Innovation, Los Angeles, CA, USA., Castells M; Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Phillips EJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Turjeman K; Laboratory of Membrane and Liposome Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Barenholz Y; Laboratory of Membrane and Liposome Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Crommelin DJA; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, the Netherlands., Dobrovolskaia MA; Nanotechnology Characterization Laboratory, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD, USA. marina@mail.nih.gov.

Publikováno v: Nature nanotechnology [Nat Nanotechnol] 2022 Apr; Vol. 17 (4), pp. 337-346. Date of Electronic Publication: 2022 Apr 07.

Liposome-Assisted Drug Delivery in the Treatment of Multiple Sclerosis.

Autor: Greco, Giuliana^1,2 (AUTHOR) giuliana.greco@phd.unict.it, Sarpietro, Maria Grazia^2,3 (AUTHOR) mg.sarpietro@unict.it

Publikováno v: Molecules. Oct2024, Vol. 29 Issue 19, p4689. 22p.

Current landscape of mRNA technologies and delivery systems for new modality therapeutics.

Autor: Lu, Ruei-Min¹ (AUTHOR), Hsu, Hsiang-En¹ (AUTHOR), Perez, Ser John Lynon P.¹ (AUTHOR), Kumari, Monika² (AUTHOR), Chen, Guan-Hong¹ (AUTHOR), Hong, Ming-Hsiang¹ (AUTHOR), Lin, Yin-Shiou¹ (AUTHOR), Liu, Ching-Hang¹ (AUTHOR), Ko, Shih-Han¹ (AUTHOR), Concio, Christian Angelo P.³ (AUTHOR), Su, Yi-Jen² (AUTHOR), Chang, Yi-Han¹ (AUTHOR), Li, Wen-Shan^1,3 (AUTHOR) wenshan@gate.sinica.edu.tw, Wu, Han-Chung^1,2 (AUTHOR) hcw0928@gate.sinica.edu.tw

Publikováno v: Journal of Biomedical Science. 9/10/2024, Vol. 31 Issue 1, p1-36. 36p.