Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Turid Nilsen"'
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Pharmacodynamic studies of naloxone require opioid agonism. Steady state condition may be achieved by remifentanil TCI (target controlled infusion). Opioid agonism can be measured by pupillometry. It is not known whether there are arterioveno
Publikováno v:
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 139(13)
Bystander administration with naloxone nasal spray can prevent deaths from opioid overdose. To achieve optimal nasal absorption of naloxone, the spray must be administered at low volume with high concentration of the drug. The study aimed to investig
Publikováno v:
Tidsskrift for Den norske legeforening.
Background Bystander administration with naloxone nasal spray can prevent deaths from opioid overdose. To achieve optimal nasal absorption of naloxone, the spray must be administered at low volume with high concentration of the drug. The study aimed
Autor:
Trond Sand, Ida Tylleskar, Øyvind Salvesen, Turid Nilsen, Ola Dale, Arne Kristian Skulberg, Sissel Skarra, Thorsteinn Loftsson
Publikováno v:
European Journal of Clinical Pharmacology
This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone formulation 8 mg/ml to intramuscular 0.8 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2851cb7a605f208fbd8a5c6bd44b2f
https://hdl.handle.net/11250/2593952
https://hdl.handle.net/11250/2593952
Autor:
Arne Kristian Skulberg, Sissel Skarra, Phatsawee Jansook, Ola Dale, Turid Nilsen, Ida Tylleskar
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Nasal naloxone is wanted for bystander administration in opioid overdose and as a needle-free alternative for emergency medical personnel. Epidemiologic studies have indicated a therapeutic effect of bystander administration of low-concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3090e03c0138679520b77f136d245e42
http://hdl.handle.net/11250/2443082
http://hdl.handle.net/11250/2443082
Autor:
Bjørn Olav Haugen, Thor Wilhelm Bjelland, Turid Nilsen, Pål Klepstad, Ola Dale, Øyvind Salvesen
Publikováno v:
Acta Anaesthesiologica Scandinavica. 58:709-715
Background The clearance of sedatives and analgesics may be reduced by therapeutic hypothermia. However, little is known about the concentrations of such drugs during rewarming. The aim of this study was to describe the serum concentrations of sedati
Publikováno v:
Drug Metabolism and Disposition. 41:214-223
Therapeutic hypothermia (TH) may induce pharmacokinetic changes that may affect the level of sedation. We have compared the disposition of morphine, midazolam, fentanyl, and propofol in TH with normothermia in man. Fourteen patients treated with TH f
Publikováno v:
Acta Medica Scandinavica. 216:93-99
Hemodialysis was performed in 6 uremic patients with either a bolus dose of 5 000 IU heparin or prostacyclin at a constant infusion rate of 5 ng/kg/min. Clinical data, plasma triglycerides (TG), free fatty acids (FFA), platelet aggregation, white blo
Publikováno v:
Acta Medica Scandinavica. 216:85-92
The lipid patterns of plasma from 6 patients on hemodialysis (HD) and 6 patients on continuous ambulatory peritoneal dialysis (CAPD) were compared and correlated to plasma toxicity as measured by the survival of human macrophages cultured in vitro. T
Autor:
Pål Klepstad, Kristin Moksnes, Turid Nilsen, Olav Magnus S. Fredheim, Ola Dale, Stein Kaasa, Anders Angelsen
Publikováno v:
European Journal of Clinical Pharmacology. 64:497-502
We have investigated the arterio-venous difference in the pharmacokinetics of 50 microg fentanyl during the first hour following nasal administration and documented its tolerability in opioid-naïve middle-aged to elderly patients.Twelve male patient