Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Turi Lombardo"'
Autor:
Concetta Ruberto, Dominique Labie, Sonia Spina, And Angela Ragusa, Maria Antonietta Buccheri, Turi Lombardo
Publikováno v:
Hemoglobin. 37:423-434
Fetal hemoglobin (Hb F) is the principal ameliorating factor of β-thalassemia (β-thal) and sickle cell disease. Persistent production in adult life is a quantitative trait regulated by loci inside or outside the β-globin gene cluster. From genome-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b38c5d5f5f68dcb79a1c425c511abe
https://doi.org/10.3109/03630269.2013.800823
https://doi.org/10.3109/03630269.2013.800823
Autor:
Disma Renda, Caterina Borgna-Pignatti, Gian Luca Forni, Maria Grazia Bisconte, Turi Lombardo, Maria Eliana Lai, Antonella Mandas, Aurelio Maggio, Antonio Piga, Maria Domenica Cappellini, Gianluca Vergine, Paolo Cianciulli
Publikováno v:
British Journal of Haematology. 124:114-117
Hepatocellular carcinoma (HCC) frequently complicates hepatic cirrhosis secondary to viral infection or iron overload. Therefore, patients affected by thalassaemia syndromes have a theoretically high risk of developing the tumour. We collected data o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec86b5e6726c78c98284db690b2c6e36
https://doi.org/10.1046/j.1365-2141.2003.04732.x
https://doi.org/10.1046/j.1365-2141.2003.04732.x
Autor:
Michele Rizzo, Crocetta Argento, Angela Vitrano, Pietro Violi, R. Malizia, Domenico Giuseppe D'Ascola, Carmelo Magnano, Aurelio Maggio, Marcello Capra, Saveria Campisi, Francesco Cantella, Francesca Valeria Commendatore, Francesco Gagliardotto, Liana Cuccia, Giovanni Giugno, Rocca Cingari, Carmelo Fidone, Maria Antonietta Romeo, Paolo Rigano, Luciano Prossomariti, Anna Meo, Paolo Cianciulli, Gaetano Roccamo, Aldo Filosa, Maria Concetta Galati, Gaetano Giuffrida, Vincenzo Caruso, Turi Lombardo, Angela Ciancio, Calogera Gerardi
The prognosis for thalassemia major has dramatically improved in the last two decades. However, many transfusion-dependent patients continue to develop progressive accumulation of iron. This can lead to tissue damage and eventually death, particularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c528499eeaa1c4acab63f412e90b29eb
http://hdl.handle.net/10447/62337
http://hdl.handle.net/10447/62337
Autor:
Caterina, Borgna-Pignatti, Gianluca, Vergine, Turi, Lombardo, Maria Domenica, Cappellini, Paolo, Cianciulli, Aurelio, Maggio, Disma, Renda, Maria Eliana, Lai, Antonella, Mandas, Gianluca, Forni, Antonio, Piga, Maria Grazia, Bisconte
Hepatocellular carcinoma (HCC) frequently complicates hepatic cirrhosis secondary to viral infection or iron overload. Therefore, patients affected by thalassaemia syndromes have a theoretically high risk of developing the tumour. We collected data o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d3c9694498eb59b4e00836cfd57a77be
http://hdl.handle.net/2318/36351
http://hdl.handle.net/2318/36351
Autor:
Angela, Ragusa, Silvestra, Amata, Turi, Lombardo, Lucia, Castiglia, Micheline, Maier-Redelsperger, Dominique, Labie, Luigi, Bernini
Publikováno v:
Haematologica. 88(10)
We report on two families in which the beta(0)-thalassemia mutation IVS2+1G--A occurs either in the homozygous or compound heterozygous condition with other beta-thalassemia determinants. In the first family the proband, homozygous for the IVS2+1 det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21badbe628b68ba08ab790e3e9af6220
https://pubmed.ncbi.nlm.nih.gov/14555304
https://pubmed.ncbi.nlm.nih.gov/14555304
Autor:
M. Lombardo, A. Ragusa, V. Frontini, S. Amata, Dominique Labie, Ronald L. Nagel, Turi Lombardo, R. Krishnamoorthy
Publikováno v:
American Journal of Hematology. 40:313-315
African admixture in Sicily has been long suspected because of the presence of the sickle gene. Nevertheless, the degree of African admixture cannot be derived from the study of HbS frequency, since this gene was most likely expanded by the selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6f002b7df37de3ceefe3667198450a
https://doi.org/10.1002/ajh.2830400413
https://doi.org/10.1002/ajh.2830400413
Autor:
Dominique Labie, Ryad Tamouza, Turi Lombardo, Flavia Fiorenza, Gino Schilirò, Claudine Lapoumeroulie, Marco Fichera, Angela Ragusa, Angela Spalletta
Publikováno v:
Human genetics. 99(3)
To evaluate the allelic frequency and genetic diversity of alpha-thalassemia defects in Sicily, both epidemiological and patient-oriented studies were carried out. For the epidemiological study, phenotypic data were collected on more than 1000 Sicili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd490d97178eb537fcc9403753f7b8b
https://pubmed.ncbi.nlm.nih.gov/9050927
https://pubmed.ncbi.nlm.nih.gov/9050927
Autor:
Concetta Ruberto, Jacques Elion, Cherif Beldjord, Rajagopal Krishnamoorthy, Turi Lombardo, A. Ragusa, Ronald L. Nagel, M. Lombardo
Publikováno v:
American journal of hematology. 40(3)
The present epidemiological study of the molecular characteristics of beta-thalassemia in Sicily was prompted by the disparate phenotypic expression (in clinical status and absolute HbF level) observed in two beta-thalassemic homozygotes who were als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bfc7c2be43eb527e6658a0715ad91c
https://pubmed.ncbi.nlm.nih.gov/1376963
https://pubmed.ncbi.nlm.nih.gov/1376963
Autor:
Carmelo Magnano, Angela Ciancio, Domenico Giuseppe D'Ascola, Michele Rizzo, Liana Cuccia, Paolo Cianciulli, Maria Antonietta Romeo, Paolo Rigano, Giovanni Giugno, Turi Lombardo, Calogera Gerardi, Carmelo Fidone, Marika Galati, Rosario Cantella, Anna Meo, Gaetano Roccamo, Francesca Valeria Commendatore, Crocetta Argento, Luciano Prossomariti, Gaetano Giuffrida, Angela Vitrano, Vincenzo Caruso, Pietro Violi, Aldo Filosa, Saveria Campisi, Aurelio Maggio, Marcello Capra, Francesco Gagliardotto, R. Malizia
Publikováno v:
Blood. 112:3885-3885
Prognosis of thalassemia major patients has dramatically improved in the past two decades. Previous papers, including retrospective and prospective non-randomised clinical trials, suggested that mortality, due mainly to cardiac damage, was less or co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::319b8b9ced4a57e26ac1bf050c394e7a
https://doi.org/10.1182/blood.v112.11.3885.3885
https://doi.org/10.1182/blood.v112.11.3885.3885
Autor:
Carmelo Magnano, R. Malizia, Domenico Giuseppe D'Ascola, Gaetano Giuffrida, Saveria Campisi, Vincenzo Caruso, Paolo Cianciulli, Aldo Filosa, Gaetano Roccamo, Turi Lombardo, Maria G. Friscia, Maria Antonietta Romeo, Francesca Valeria Commendatore, Crocetta Argento, Calogera Gerardi, Carmelo Fidone, Anna Meo, Michele Rizzo, Marika Galati, Gennaro D'Amico, Alberto Fragasso, Aurelio Maggio, Roberto Giugno, Marcello Capra, Francesco Gagliardotto, Pietro Violi, Alessia Pepe, Alberto Morabito, Francesco Cantella, Liana Cuccia
Publikováno v:
Blood. 110:575-575
Three short-term randomised clinical trials suggested not difference of Deferiprone (L1) vs Deferoxamine (DFO) in term of iron overload efficacy in thalassemia major (TM) patients. To assess whether L1 (75mg/Kg) alone was comparable to a sequential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ec8bc825db6484cee59c3ccfea7db1
https://doi.org/10.1182/blood.v110.11.575.575
https://doi.org/10.1182/blood.v110.11.575.575