Zobrazeno 1 - 10
of 320
pro vyhledávání: '"TurboID"'
Autor:
Natsuki Shinoda, Masayuki Miura
Publikováno v:
Frontiers in Cell Death, Vol 3 (2024)
Caspases are cysteine aspartic acid proteases conserved in animals that not only execute apoptosis, but also regulate diverse cellular processes independent of apoptosis, which are termed caspase-dependent non-lethal cellular processes (CDPs). Owing
Externí odkaz:
https://doaj.org/article/b0341022f059485084af6da60e9e8636
Autor:
Zhi-Wei Zhang, Meng Wang, Li-Xiu Sun, Hany M. Elsheikha, Cheng-Lin Lei, Jin-Lei Wang, Bao-Quan Fu, Jian-Xun Luo, Xing-Quan Zhu, Ting-Ting Li
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background To successfully replicate within the host cell, Toxoplasma gondii employs several mechanisms to overcome the host cell defenses and mitigate the harmful effects of the free radicals resulting from its own metabolic processes using
Externí odkaz:
https://doaj.org/article/d5526581245047be8aa269604713f5e4
Publikováno v:
eLife, Vol 13 (2024)
Immunofluorescence localises proteins via fluorophore-labelled antibodies. However, some proteins evade detection due to antibody-accessibility issues or because they are naturally low abundant or antigen density is reduced by the imaging method. Her
Externí odkaz:
https://doaj.org/article/7935edb07619427ea4286357d94e9d4a
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Virus receptors determine the tissue tropism of viruses and have a certain relationship with the clinical outcomes caused by viral infection, which is of great importance for the identification of virus receptors to understand the infection mechanism
Externí odkaz:
https://doaj.org/article/455a1f4ddfbd4660a60d3815330d54f8
Autor:
Max Petersen, Anna Chorzalska, Makayla Pardo, Anaelena Rodriguez, John Morgan, Nagib Ahsan, Ting C. Zhao, Olin Liang, Leszek Kotula, Paul Bertone, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2356-2379 (2023)
Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity‐dependent labeling (PDL) with biotin follo
Externí odkaz:
https://doaj.org/article/9feb2424ca384d45925ebb57c2e9eae4
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Protein‒protein, protein‒RNA, and protein‒DNA interaction networks form the basis of cellular regulation and signal transduction, making it crucial to explore these interaction networks to understand complex biological processes. Tradi
Externí odkaz:
https://doaj.org/article/799bf1f5074c4df399069d6cf42c7240
Autor:
Yaofang Hu, Changsheng Jiang, Yueqiao Zhao, Hua Cao, Jingping Ren, Wei Zeng, Mengjia Zhang, Yongtao Li, Qigai He, Wentao Li
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-14 (2023)
Abstract Actinobacillus pleuropneumoniae (APP) is a gram-negative pathogenic bacterium responsible for porcine contagious pleuropneumonia (PCP), which can cause porcine necrotizing and hemorrhagic pleuropneumonia. Actinobacillus pleuropneumoniae-RTX-
Externí odkaz:
https://doaj.org/article/41e9189903d04ae4b05cafc364c17abb
Publikováno v:
Plant Direct, Vol 7, Iss 12, Pp n/a-n/a (2023)
Abstract Proximity labeling was recently developed to detect protein–protein interactions and members of subcellular multiprotein structures in living cells. Proximity labeling is conducted by fusing an engineered enzyme with catalytic activity, su
Externí odkaz:
https://doaj.org/article/6d1346e139fb4b81ae3e4d794cae3bd6
Publikováno v:
Redox Report, Vol 28, Iss 1 (2023)
ABSTRACTBackground Methionine sulfoxide reductases are found in all aerobic organisms. They function in antioxidant defense, cellular regulation by reversible oxidation of methionine in proteins, and in protein structure. However, very few in vivo bi
Externí odkaz:
https://doaj.org/article/c029bc9868a6416093526019eff81f90
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Protein‒protein interactions (PPIs) are the foundation of the life activities of cells. TurboID is a biotin ligase with higher catalytic efficiency than BioID or APEX that reduces the required labeling time from 18 h to 10 min.
Externí odkaz:
https://doaj.org/article/9b68ff5b7f5a420bb8c685f58b6d0924