Werner syndrome protein prevents DNA breaks upon chromatin structure alteration.

Autor: Turaga, Ramachander V. N.¹, Massip, Laurent¹, Chavez, Alejandro², Johnson, F. Brad², Lebel, Michel¹ michel.lebel@crhdq.ulaval.ca

Publikováno v: Aging Cell. Aug2007, Vol. 6 Issue 4, p471-481. 11p. 1 Color Photograph, 3 Black and White Photographs, 4 Graphs.

Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue.

Autor: Massip L; Centre de Recherche en Cancérologie de l'Université Laval, Hôpital Hôtel-Dieu de Québec, CHUQ, 9 McMahon St, Québec, Qué., Canada G1R 2J6., Garand C, Turaga RV, Deschênes F, Thorin E, Lebel M

Publikováno v: Experimental gerontology [Exp Gerontol] 2006 Feb; Vol. 41 (2), pp. 157-68. Date of Electronic Publication: 2005 Dec 05.