Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tupa Basuroy"'
Autor:
Archit Trivedi, Aanchal Mehrotra, Caitlin E. Baum, Brandon Lewis, Tupa Basuroy, Thomas Blomquist, Robert Trumbly, Fabian V. Filipp, Vijayasaradhi Setaluri, Ivana L. de la Serna
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Pharmacologic inhibition of bromodomain and extra-terminal (BET) proteins is currently being explored as a new therapeutic approach in cancer. Some studies have also implicated BET proteins as regulators of cell identity and diffe
Externí odkaz:
https://doaj.org/article/3388d5c1150043a58943b8a9ef32ec3a
Autor:
Ila Datar, Gardiyawasam Kalpana, Jungmin Choi, Tupa Basuroy, Robert Trumbly, Sri Krishna Chaitanya Arudra, Michael D McPhee, Ivana de la Serna, Kam C Yeung
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0204387 (2019)
Recent high-throughput-sequencing of cancer genomes has identified oncogenic mutations in the B-Raf genetic locus as one of the critical events in melanomagenesis. B-Raf encodes a serine/threonine kinase that regulates the MAPK/ERK kinase (MEK) and e
Externí odkaz:
https://doaj.org/article/9aa92ab37aad431c84285c9996b27860
Autor:
Tupa Basuroy, Megan Dreier, Caitlin Baum, Thomas Blomquist, Robert Trumbly, Fabian V. Filipp, Ivana L. de la Serna
Publikováno v:
Pigment Cell Melanoma Res. 36, 19-32 (2023)
Lineage-specific differentiation programs are activated by epigenetic changes in chromatin structure. Melanin-producing melanocytes maintain a gene expression program ensuring appropriate enzymatic conversion of metabolites into the pigment, melanin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68a6cc7d1a03fa12b76e28d35f8c92b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66392
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66392
Autor:
Vijayasaradhi Setaluri, Caitlin E. Baum, Ivana L. de la Serna, Brandon Lewis, Thomas M. Blomquist, Tupa Basuroy, Robert J. Trumbly, Archit R. Trivedi, Aanchal Mehrotra, Fabian V. Filipp
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-18 (2020)
Epigenetics Chromatin 13:14 (2020)
Epigenetics & Chromatin
Epigenetics Chromatin 13:14 (2020)
Epigenetics & Chromatin
BackgroundPharmacologic inhibition of bromodomain and extra-terminal (BET) proteins is currently being explored as a new therapeutic approach in cancer. Some studies have also implicated BET proteins as regulators of cell identity and differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc5d4c65f2e1a773a923abaa01ccad0
http://link.springer.com/article/10.1186/s13072-020-00333-z
http://link.springer.com/article/10.1186/s13072-020-00333-z
Autor:
Cory M. Howard, Ivana L. de la Serna, Sangita Sridharan, Boopathi Subramaniyan, Tupa Basuroy, Dayanidhi Raman, Augustus M C Tilley, Elke Butt
Publikováno v:
Cancers, Vol 12, Iss 2372, p 2372 (2020)
Cancers
Volume 12
Issue 9
Cancers
Volume 12
Issue 9
The CXCL12-CXCR4 axis plays a vital role in many steps of breast cancer metastasis, but the molecular mechanisms have not been fully elucidated. We previously reported that activation of CXCR4 by CXCL12 promotes the nuclear localization of LASP1 (LIM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897b210cdcb302cd30b5d770e73d39f8
https://www.mdpi.com/2072-6694/12/9/2372
https://www.mdpi.com/2072-6694/12/9/2372
Autor:
Archit Trivedi, Aanchal Mehrotra, Baum, Caitlin E., Lewis, Brandon, Tupa Basuroy, Blomquist, Thomas, Trumbly, Robert, Filipp, Fabian V., Vijayasaradhi Setaluri, Serna, Ivana L. De La
Additional file 3: Fig. S3. Melb-a cells were differentiated for 48 h in the presence of vehicle or 500nM +JQ1. RNA was isolated and subjected to RNA-seq. Differential gene expression ((+)JQ1 vs. Vehicle) was determined based on the average of three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2c40d2dd85028e4c4d0ba19e6d441c
Autor:
Archit Trivedi, Aanchal Mehrotra, Baum, Caitlin E., Lewis, Brandon, Tupa Basuroy, Blomquist, Thomas, Trumbly, Robert, Filipp, Fabian V., Vijayasaradhi Setaluri, Serna, Ivana L. De La
Additional file 2: Fig. S2. Neonatal human epidermal melanocytes (NHEMs) were cultured in the presence of vehicle (VC) or 500nM (+)JQ1 for the indicated number of days. Cells were pelleted and photographed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bc306cf3feae63e94592cb0eeb3684
Autor:
Archit Trivedi, Aanchal Mehrotra, Baum, Caitlin E., Lewis, Brandon, Tupa Basuroy, Blomquist, Thomas, Trumbly, Robert, Filipp, Fabian V., Vijayasaradhi Setaluri, Serna, Ivana L. De La
Additional file 1: Fig. S1. Melb-a cells were differentiated for the indicated number of days in vehicle (VC) or 500 nM PFI-1. Cells were pelleted and photographed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d70fc3cb6d46c91a99e8ab7b41b904a
Autor:
Gaurav Mehta, Ivana L. de la Serna, Matthias Weider, Himangi Marathe, Michael Wegner, Alana Hoffmann, Aanchal Mehrotra, Tupa Basuroy, Dawn E. Watkins-Chow, Dorothy C. Bennett, Shweta Aras, Archit R. Trivedi, William J. Pavan
Publikováno v:
Nucleic Acids Research
Mutations in SOX10 cause neurocristopathies which display varying degrees of hypopigmentation. Using a sensitized mutagenesis screen, we identified Smarca4 as a modifier gene that exacerbates the phenotypic severity of Sox10 haplo-insufficient mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc66e9aea86bc5d3e7fa101f3ba012c4
https://doi.org/10.1093/nar/gkx259
https://doi.org/10.1093/nar/gkx259
Autor:
Sri Krishna Chaitanya Arudra, Kam C. Yeung, Gardiyawasam Kalpana, Jungmin Choi, Ila Datar, Ivana L. de la Serna, Michael D. McPhee, Robert J. Trumbly, Tupa Basuroy
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0204387 (2019)
Recent high-throughput-sequencing of cancer genomes has identified oncogenic mutations in the B-Raf genetic locus as one of the critical events in melanomagenesis. B-Raf encodes a serine/threonine kinase that regulates the MAPK/ERK kinase (MEK) and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863f590c7a713d7686dabe45b9f526f0
https://pubmed.ncbi.nlm.nih.gov/30995246
https://pubmed.ncbi.nlm.nih.gov/30995246