Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tuomo Nikula"'
Autor:
Michael Dr.-Ing. Schilp, Joachim Sciuk, H. Wengenmair, Arndt Rimpler, Ilona Barth, G. Leissner, Oliver Buck, Tuomo Nikula, J. Kopp
Publikováno v:
Zeitschrift für Medizinische Physik. 19:193-199
Zusammenfassung Die endovaskulare Brachytherapie mit Hilfe eines mit Re-188-Losung gefullten Ballonkatheters ist eine Erfolg versprechende Methode zur Restenoseprophylaxe nach perkutaner transluminaler Angioplastie (PTA) im peripheren Stromgebiet. Da
Autor:
Sabine Seidenschwang, Roswitha Beck, Hedwig Schröck, E Schmid, Markus Schwaiger, Karl-Friedrich Becker, Christof Seidl, Christos Apostolidis, Reingard Senekowitsch-Schmidtke, Tuomo Nikula, Elisabeth Kremmer, Michael Abend
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 32:274-285
Radioimmunotherapy with alpha-particle-emitting nuclides, such as 213Bi, is a promising concept for the elimination of small tumour nodules or single disseminated tumour cells. The aim of this study was to investigate cellular damage and the mode of
Autor:
Matthias Miederer, Christof Seidl, Jozef J. Comor, Karl-Friedrich Becker, Roswitha Huber, Reingard Senekowitsch-Schmidtke, Sanja Vranjes-Duric, D. E. Charlton, Gerd-Jurgen Beyer, Christoph Schuhmacher, Christos Apostolidis, Tuomo Nikula
Publikováno v:
Radiation Research
We investigated the effects of the a-particle emitters Tb-149 and Bi-213 coupled to a tumor-specific antibody targeting the mutated delta 9 E-cadherin (d9 E-Cad) on single cells and cell pellets. The d9 mutation of the adhesion molecule E-cadherin is
Autor:
Kari Åkerman, Tuomo Nikula, Jukka Hiltunen, Jari Tiihonen, Jyrki T. Kuikka, Kim A. Bergström, Christian Foged, Christer Halldin, Simo Lötjönen, Meixiang Yu
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 13:177-182
The imidazobenzodiazepine derivate 123I-labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)-7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine (NNC 13–8241) is a partial benzodiazepine agonist and binds with a high affinity to the b
Publikováno v:
Cell Adhesion and Communication. 5:325-333
Rhenium (Re)-188 is a generator (W-188/Re-188) produced high energy beta-emitter suitable for radionuclide therapy (T1/2 is 16.9 hrs and Emax 2.1 MeV (range 11 mm)). We have labelled monoclonal antibody (MAb) raised against vascular cell adhesion mol
Publikováno v:
The Journal of Physiology. 504:233-239
1. The effects of dynamic and isometric muscle contractions on the lymph flow dynamics in human skeletal muscle were studied with a scintographic method. 2. Radioactively labelled human serum albumin (99mTc-HSA) was injected bilaterally into the vast
Autor:
Tuomo Nikula, R. Molinet, W Janssens, A. Ouadi, R. Carlos-Marquez, Christos Apostolidis, M. Betti
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S806-S808
Autor:
Ilona, Barth, Arndt, Rimpler, Tuomo, Nikula, Michael, Schilp, Oliver, Buck, Hermann, Wengenmair, Giesbert, Leissner, Jürgen, Kopp, Joachim, Sciuk
Publikováno v:
Zeitschrift fur medizinische Physik. 19(3)
Endovascular brachytherapy using a balloon catheter filled with Re-188 solution is a promising method for the prophylaxis of restenosis in peripheral blood circulation after percutaneous transluminal angioplasty (PTA) treatments. Thereby about 20 GBq
Autor:
Roswitha, Huber, Christof, Seidl, Ernst, Schmid, Sabine, Seidenschwang, Karl-Friedrich, Becker, Christoph, Schuhmacher, Christos, Apostolidis, Tuomo, Nikula, Elisabeth, Kremmer, Markus, Schwaiger, Reingard, Senekowitsch-Schmidtke
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(10 Pt 2)
The locoregional application of tumor-specific antibodies conjugated with highly cytotoxic alpha-emitters is a promising new strategy for therapy of i.p. tumor cell dissemination. Using this approach, an antibody specifically targeting diffuse-type g
Autor:
K Vandenbulcke, Filip De Vos, Hubert Thierens, Guido Slegers, Klaus Bacher, R. Molinet, Christophe Lahorte, Fritz Offner, Jan Philippé, Virginie de Gelder, Christos Apostolidis, Rudi Dierckx, Tuomo Nikula, Anne Vral
Publikováno v:
European journal of nuclear medicine and molecular imaging. 30(10)
External source radiotherapy and beta radioimmunotherapy (RIT) are effective treatments for lymphoid malignancies. The development of RIT with alpha emitters is attractive because of the high linear energy transfer (LET) and short path length, allowi