Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tuomas Komulainen"'
Autor:
Tuomas Komulainen, Patrik Daymond, Kristiina E. Hietanen, Ilkka S. Kaartinen, Tero A. H. Järvinen
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionKeloids form as a pathological response to skin wound healing, and their etiopathology is poorly understood. Myofibroblasts, which are cells transformed from normal fibroblasts, are believed to contribute to pathological scar formation in
Externí odkaz:
https://doaj.org/article/78c2083641ed4a5d94a1923c4686c8eb
Autor:
Reetta Kälviäinen, Johanna Arola, Leena Jutila, Johanna Hynynen, Kari Majamaa, Matias Röyttä, Heikki Mäkisalo, Eija Tukiainen, Tuomas Komulainen, Reetta Hinttala, Arno Nordin, Johanna Uusimaa
Publikováno v:
Liver Transplantation. 20:1402-1412
Patients with mutations in the POLG1 gene encoding mitochondrial DNA polymerase gamma have an increased risk of valproate-induced liver failure. POLG1 mutations are common, and these patients often suffer from intractable seizures. The role of liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9aa8e771cdded7822daf7a5751f6d0
https://doi.org/10.1002/lt.23965
https://doi.org/10.1002/lt.23965
Autor:
Peppi Koivunen, Tiffany Lodge, Mika Pietilä, Jukka Hakkola, Tuomas Komulainen, Karl J. Morten, Reetta Hinttala, Johanna Uusimaa, Joanna Poulton, Maija Bolszak
Publikováno v:
Toxicology. 331
Sodium valproate (VPA) is a potentially hepatotoxic antiepileptic drug. Risk of VPA-induced hepatotoxicity is increased in patients with mitochondrial diseases and especially in patients with POLG1 gene mutations. We used a HepG2 cell in vitro model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c03a2ed82ed92758e130f243cc4c0d8
https://pubmed.ncbi.nlm.nih.gov/25745980
https://pubmed.ncbi.nlm.nih.gov/25745980
Autor:
Johanna Uusimaa, Reetta Hinttala, Outi Saarenpää-Heikkilä, Vesa Vähäsarja, Päivi Vieira, Hannu Tuominen, Heikki Rantala, Tuomas Komulainen, Petri Lehenkari, Päivi Olsén, Pietari Kinnunen, Salla Pakanen, Johanna Palmio, Kari Majamaa, Milla-Riikka Hautakangas
Publikováno v:
JIMD Reports ISBN: 9783662474662
To study the clinical manifestations and occurrence of mtDNA depletion and deletions in paediatric patients with neuromuscular diseases and to identify novel clinical phenotypes associated with mtDNA depletion or deletions.Muscle DNA samples from pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c8e834b1cb3f857d4a5e012b4310e1
https://pubmed.ncbi.nlm.nih.gov/25940035
https://pubmed.ncbi.nlm.nih.gov/25940035
Autor:
Johanna, Hynynen, Tuomas, Komulainen, Eija, Tukiainen, Arno, Nordin, Johanna, Arola, Reetta, Kälviäinen, Leena, Jutila, Matias, Röyttä, Reetta, Hinttala, Kari, Majamaa, Heikki, Mäkisalo, Johanna, Uusimaa
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 20(11)
Patients with mutations in the POLG1 gene encoding mitochondrial DNA polymerase gamma have an increased risk of valproate-induced liver failure. POLG1 mutations are common, and these patients often suffer from intractable seizures. The role of liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::650e5b892094549e092b5cae57fb044b
https://pubmed.ncbi.nlm.nih.gov/25179873
https://pubmed.ncbi.nlm.nih.gov/25179873
Autor:
Annakaisa Reponen, Sari Lindeman, Tuomas Komulainen, Anna-Maria Keränen, Elsi Rasinaho, Hellinä Hakko, Mona-Lisa Kujari, Markku J. Savolainen
Publikováno v:
International Journal of Circumpolar Health; Vol 70, No 1 (2011)
Objectives. To examine whether a diagnosis for major depression, chronic depression or specific symptoms of depression is associated with the risk of quitting a weight loss program. Study design. The study involved 82 overweight adults participating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbd8ee47803bb55edddd4c14edca1e1
http://www.circumpolarhealthjournal.net/index.php/ijch/article/view/17795
http://www.circumpolarhealthjournal.net/index.php/ijch/article/view/17795
Autor:
Maija Bolszak, Riitta Herva, Johanna Uusimaa, Tuomas Komulainen, Anna-Kaisa Anttonen, Raija Sormunen, Anna-Elina Lehesjoki, Heikki Rantala, Salla Pakanen, Reetta Hinttala, Kari Majamaa
Publikováno v:
Epilepsy research. 85(2-3)
The clinical features of severe myoclonic epilepsy of infancy (SMEI) resemble those of mitochondrial diseases, although most patients have the sodium channel (SCN1A) mutation. We describe a patient with SMEI and enlarged muscle mitochondria associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0c5cc849f00eb8a9d24cab11fa8278
https://pubmed.ncbi.nlm.nih.gov/19359143
https://pubmed.ncbi.nlm.nih.gov/19359143
Autor:
P. Kinnunen, Tuomas Komulainen, Päivi Olsén, Hannu Tuominen, V. Vähäsaija, Päivi Vieira, Petri Lehenkari, Johanna Uusimaa, Heikki Rantala, Salla Pakanen, O. Saarenpää-Heikkilä, J. Palmio, Reetta Hinttala, Kari Majamaa, Milla-Riikka Hautakangas
Publikováno v:
European Journal of Paediatric Neurology. 19:S15
Objective To study the clinical manifestations and occurrence of mtDNA depletion and deletions in paediatric patients with neuromuscular diseases, in order to estimate the role of mtDNA rearrangements in pathogenesis of these diseases and to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ac0582fd29fc50936bf91ba01ee586
https://doi.org/10.1016/s1090-3798(15)30047-7
https://doi.org/10.1016/s1090-3798(15)30047-7
Autor:
Marjo-Riitta Järvelin, Kaisa Saari, Hannu Koponen, M. Tuomas Komulainen, Jaana Laitinen, Helinä Hakko, Sari Lindeman
Publikováno v:
Schizophrenia research. 84(1)
Obesity is a serious health problem, especially in patients with long-term mental disorders. We explored the socio-demographic, psychiatric, and clinical factors that increase the risk of changing from under- or normal weight in adolescence to overwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ef06681d71562933462df2b51de53e
https://pubmed.ncbi.nlm.nih.gov/16626939
https://pubmed.ncbi.nlm.nih.gov/16626939
Autor:
Tuomas Komulainen
This study shows that due to herding behaviour and possible capital outflows, emerging market countries are vulnerable to multiple equilibria situations and currency crises. It uses a model by Jeanne (1997), where currency crises can be formed by mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bb2d830ce2ab301dff536baa9efdbd
http://www.suomenpankki.fi/bofit_en/tutkimus/tutkimusjulkaisut/dp/Documents/dp1001.pdf
http://www.suomenpankki.fi/bofit_en/tutkimus/tutkimusjulkaisut/dp/Documents/dp1001.pdf
