Sex specific differences in hepatic and plasma lipid profiles in healthy cats pre and post spaying and neutering: relationship with feline hepatic lipidosis

Autor: Valtolina, Chiara, Vaandrager, Arie B, Favier, Robert P, Tuohetahuntila, Maidina, Kummeling, Anne, Jeusette, Isabelle, Rothuizen, Jan, Robben, Joris H, dB&C FR-RMSC FR, dCSCA AVR

Publikováno v: BMC Veterinary Research, Vol 13, Iss 1, Pp 1-9 (2017)
BMC Veterinary Research, 13(1). BioMed Central
BMC Veterinary Research

Background A link between lipid metabolism and disease has been recognized in cats. Since hepatic lipidosis is a frequent disorder in cats, the aim of the current study was to evaluate liver and plasma lipid dimorphism in healthy cats and the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a15b8357d9eec9e8f762f00c9f707a
http://link.springer.com/article/10.1186/s12917-017-1152-y

No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats

Autor: Valtolina, Chiara, Vaandrager, Arie B, Favier, Robert P, Robben, Joris H, Tuohetahuntila, Maidina, Kummeling, Anne, Jeusette, Isabelle, Rothuizen, Jan, Applied Veterinary Research, Risk Assessment, Infection & Immunity, Fertility & Reproduction, dCSCA AVR, dCSCA RMSC-1, dB&C FR-RMSC FR, dB&C I&I, Intensieve Zorgafdeling, LS Veterinaire biochemie, Sub Hepatologie, LS Algemene chirurgie, LS Interne geneeskunde

Publikováno v: BMC Veterinary Research, 11(1). BioMed Central
BMC Veterinary Research

BACKGROUND: Feline hepatic lipidosis (FHL) is a common cholestatic disease affecting cats of any breed, age and sex. Both choline deficiency and low hepatic phosphatidylethanolamine N-methyltransferase (PEMT) activity are associated with hepatic lipi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4482ad58147fc62bbe416ec14187bf
https://dspace.library.uu.nl/handle/1874/327201

Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells

Autor: Tuohetahuntila, Maidina, Spee, Bart, Kruitwagen, Hedwig S, Wubbolts, Richard, Brouwers, Jos F, van de Lest, Chris H, Molenaar, Martijn R, Houweling, Martin, Helms, J Bernd, Vaandrager, Arie B, Fertility & Reproduction, Regenerative Medicine, Stem Cells & Cancer, dB&C FR-RMSC FR, dB&C I&I, Infection & Immunity, Onderzoek, LS Celbiologie-Algemeen, Sub Center for Cell Imaging, LS Veterinaire biochemie, Sub MS-faciliteit, LS Equine Muscoskeletal Biology, Sub Biochemie Algemeen, Dep Biochemie en Celbiologie, LS Algemeen B&C

Publikováno v: Biochimica et Biophysica Acta, 1851(2), 220

Hepatic stellate cell (HSC) activation is a critical step in the development of chronic liver disease. We previously observed that the levels of triacylglycerol (TAG) species containing long polyunsaturated fatty acids (PUFAs) are increased in in vit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7b71d13f6e204c6c52bad7f13aa9d9
https://doi.org/10.1016/j.bbalip.2014.12.003

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No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats.

Autor: Valtolina C; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands. c.valtolina@uu.nl., Vaandrager AB; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine and Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM, Utrecht, The Netherlands. a.b.vaandrager@uu.nl., Favier RP; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands. r.p.favier@uu.nl., Robben JH; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands. j.h.robben@uu.nl., Tuohetahuntila M; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine and Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM, Utrecht, The Netherlands. t.maidina@uu.nl., Kummeling A; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands. a.kummeling@uu.nl., Jeusette I; Research and Development, Affinity Petcare, Pl. Xavier Cugat, 2 Edificio D, 3ª, Planta, 08174 St. Cugat del Vallès, Barcelona, Spain. ijeusette@affinity-petcare.com., Rothuizen J; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands. j.rothuizen@uu.nl.

Publikováno v: BMC veterinary research [BMC Vet Res] 2015 Nov 09; Vol. 11, pp. 280. Date of Electronic Publication: 2015 Nov 09.