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pro vyhledávání: '"Tuo-Xian Tang"'
Publikováno v:
Biomol NMR Assign
Phafin2 is a peripheral protein that triggers cellular signaling from endosomal and lysosomal compartments. The specific subcellular localization of Phafin2 is mediated by the presence of a tandem of phosphatidylinositol 3-phosphate (PtdIns3P)-bindin
Autor:
Anne M. Brown, Daniel G. S. Capelluto, Carla V. Finkielstein, Andrew Biscardi, Wei Song, Jeffrey F. Ellena, Carter J. Gottschalk, Tuo-Xian Tang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Disabled-2 (Dab2) is an adaptor protein that regulates the extent of platelet aggregation by two mechanisms. In the first mechanism, Dab2 intracellularly downregulates the integrin alpha (IIb)beta (3) receptor, converting it to a low affinity state f
Publikováno v:
Biophysical Journal. 121:82a
Publikováno v:
Sensors and Actuators B: Chemical. 243:650-657
Lab-on-a-chip applications rely on the ability to deliver and manipulate pico/nanoliter volumes of liquid. The presence of air bubbles interferes with the stable operation of microfluidic devices leading potentially to catastrophic failures. In this
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1862(6)
Changes in membrane curvature are required to control the function of subcellular compartments; malfunctions of such processes are associated with a wide range of human diseases. Membrane remodeling often depends upon the presence of phosphoinositide
Publikováno v:
Biophysical Journal. 120:230a
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1647
The protein-lipid overlay assay is an inexpensive, easy-to-implement, and high-throughput methodology that employs nitrocellulose membranes to immobilize lipids in order to rapid screen and identify protein-lipid interactions. In this chapter, we sho
Autor:
Wen Xiong, Carla V. Finkielstein, Jeffrey F. Ellena, Shuyan Xiao, Daniel G. S. Capelluto, Xiaolin Zhao, Tuo-Xian Tang, Geoffrey S. Armstrong
Publikováno v:
Scientific Reports
Pathogen-activated Toll-like receptors (TLRs), such as TLR2 and TLR4, dimerize and move laterally across the plasma membrane to phosphatidylinositol (4,5)-bisphosphate-enriched domains. At these sites, TLRs interact with the TIR domain-containing ada
Publikováno v:
Methods in Molecular Biology ISBN: 9781493972005
The protein-lipid overlay assay is an inexpensive, easy-to-implement, and high-throughput methodology that employs nitrocellulose membranes to immobilize lipids in order to rapid screen and identify protein-lipid interactions. In this chapter, we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2300a253e302085ef06650842b5ce8e1
https://doi.org/10.1007/978-1-4939-7201-2_13
https://doi.org/10.1007/978-1-4939-7201-2_13
Autor:
Tuo-Xian Tang
Publikováno v:
Biophysical Journal. 112:495a
Phafin2 is a phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding protein involved in the regulation of endosomal cargo trafficking and in the lysosomal induction of autophagy. Binding of Phafin2 to PtdIns(3)P is mediated by both its PH and FYVE dom