Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Tuo Deng"'
Autor:
Xia Qiu, Hedong Zhang, Zhouqi Tang, Yuxi Fan, Wenjia Yuan, Chen Feng, Chao Chen, Pengcheng Cui, Yan Cui, Zhongquan Qi, Tengfang Li, Yuexing Zhu, Liming Xie, Fenghua Peng, Tuo Deng, Xin Jiang, Longkai Peng, Helong Dai, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 12, Pp 1453-1464 (2024)
Abstract. Background:. Homoharringtonine (HHT) is an effective anti-inflammatory, anti-viral, and anti-tumor protein synthesis inhibitor that has been applied clinically. Here, we explored the therapeutic effects of HHT in a mouse heart transplant mo
Externí odkaz:
https://doaj.org/article/f1c8744cb5b14f39a49dbb5d2d3abb65
Autor:
Qin Zeng, Jianfeng Song, Xiaoxiao Sun, Dandan Wang, Xiyan Liao, Yujin Ding, Wanyu Hu, Yayi Jiao, Wuqian Mai, Wufuer Aini, Fanqi Wang, Hui Zhou, Limin Xie, Ying Mei, Yuan Tang, Zhiguo Xie, Haijing Wu, Wei Liu, Tuo Deng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Ten-eleven translocation (TET) 2 is an enzyme that catalyzes DNA demethylation to regulate gene expression by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine, functioning as an essential epigenetic regulator in various biological proce
Externí odkaz:
https://doaj.org/article/fcb87b2f32094238a0283b1fb7d3cb6e
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundInflammatory bowel disease (IBD) is a group of diseases characterized by chronic and recurrent inflammation of the gastrointestinal tract. The etiology of IBD remains multifaceted and poorly understood, resulting in limited treatment option
Externí odkaz:
https://doaj.org/article/dddafd0f39984693932807cd52a23276
Autor:
Xiyan Liao, Qin Zeng, Limin Xie, Haowei Zhang, Wanyu Hu, Liuling Xiao, Hui Zhou, Fanqi Wang, Wanqin Xie, Jianfeng Song, Xiaoxiao Sun, Dandan Wang, Yujin Ding, Yayi Jiao, Wuqian Mai, Wufuer Aini, Xiaoyan Hui, Wei Liu, Willa A. Hsueh, Tuo Deng
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113963- (2024)
Summary: T cell infiltration into white adipose tissue (WAT) drives obesity-induced adipose inflammation, but the mechanisms of obesity-induced T cell infiltration into WAT remain unclear. Our single-cell RNA sequencing reveals a significant impact o
Externí odkaz:
https://doaj.org/article/57fce9b83d8041aeb1c2f03a6252fef2
Autor:
Zude Chen, Xiaoshuang Yang, Zugen Chen, Minzhao Li, Wei Wang, Riwei Yang, Zuomin Wang, Yuxiang Ma, Yulong Xu, Shan Ao, Leqi Liang, Chao Cai, Changning Wang, Tuo Deng, Di Gu, Hongqing Zhou, Guohua Zeng
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Prostate cancer (PCa) is the most common malignancy diagnosed in men. Immune checkpoint blockade (ICB) alone showed disappointing results in PCa. It is partly due to the formation of immunosuppressive tumor microenvironment (TME)
Externí odkaz:
https://doaj.org/article/8172630b3a68414aab193319f3c377d9
Autor:
Liming Deng, Wenming Bao, Baofu Zhang, Sina Zhang, Ziyan Chen, Xuewen Zhu, Bangjie He, Lijun Wu, Xiaohu Chen, Tuo Deng, Bo Chen, Zhengping Yu, Yi Wang, Gang Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-13 (2023)
Abstract Intrahepatic cholangiocarcinoma (ICC) is a primary liver malignancy and is characterized by highly aggressive and malignant biological behavior. Currently, effective treatment strategies are limited. The effect of lenvatinib on ICC is unknow
Externí odkaz:
https://doaj.org/article/84741e4629b54363a1ce73514cb84fe9
Autor:
Tuo Deng, Dongxiu Gao, Xuemei Song, Zhipeng Zhou, Lixiao Zhou, Maixian Tao, Zexiu Jiang, Lian Yang, Lan Luo, Ankun Zhou, Lin Hu, Hongbo Qin, Mingyi Wu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Natural adhesives have received a lot of attention recently. Here, the authors develop a natural biological adhesive from snail mucus that can adhere to wet tissue and be used to accelerate healing of skin wounds.
Externí odkaz:
https://doaj.org/article/994234c0e0634876961463caaa86a466
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Vaginally assisted laparoscopic sacrocolpopexy (VALS) refers to the placement of synthetic meshes through the vagina in addition to traditional laparoscopic sacrocolpopexy. In this study, we aimed to investigate the medium- to lon
Externí odkaz:
https://doaj.org/article/084da05fa95243bf80fec5ce566a3271
Impact of sarcopenia on outcomes of patients undergoing liver resection for hepatocellular carcinoma
Autor:
Jinhuan Yang, Kaiwen Chen, Chongming Zheng, Kaiyu Chen, Jian Lin, Qishan Meng, Ziyan Chen, Liming Deng, Haitao Yu, Tuo Deng, Zhiyuan Bo, Qikuan He, Yi Wang, Gang Chen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 5, Pp 2383-2392 (2022)
Abstract Background Previous studies have indicated that sarcopenia is associated with poor post‐operative outcomes in liver cancer patients, but the studies are limited by confounding from mixed diseases, retrospective data, and non‐standardized
Externí odkaz:
https://doaj.org/article/415ed0534de7405b9c79ed463f5ceaf7
Autor:
Xinzhi Li, Kaixin Ding, Xueying Li, Bingchuan Yuan, Yuqin Wang, Zhicheng Yao, Shuaikang Wang, He Huang, Bolin Xu, Liwei Xie, Tuo Deng, Xiao-wei Chen, Zheng Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Ectopic lipid accumulation and inflammation are the essential signs of NASH. Here, the authors show that hepatic WTAP is a key integrative repressor of ectopic lipid accumulation and inflammation during NASH progression, and hepatic deletion of Wtap
Externí odkaz:
https://doaj.org/article/967c9453207440ac8b112043c8a2cc1a