Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tung-Wei Hou"'
HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes
Autor:
Nancy Palechor-Ceron, Xuefeng Liu, Ewa Krawczyk, Thomas Ried, Jan Blancato, Siddartha Paul, Seema Agarwal, Richard Schlegel, Bassem R. Haddad, Naidong Wang, Danny Wangsa, Tung Wei Hou, Faris Alkhilaiwi, Christopher Albanese, Hang Yuan, Shuang Fang, Dan Zhou, Yukari Usuda, Maura L. Gillison, Sujata Choudhary, Yun Ling Zheng, David E. Symer, Aleksandra Dakic, Dan P. Hartmann
Publikováno v:
Scientific Reports
Using conditional cell reprogramming, we generated a stable cell culture of an extremely rare and aggressive neuroendocrine cervical cancer. The cultured cells contained HPV-16, formed colonies in soft agar and rapidly produced tumors in immunodefici
Autor:
Christopher Albanese, Thomas N. Darling, Seema Agarwal, Anatoly Dritschilo, Nancy Palechor-Ceron, Rajesh L. Thangapazham, Sujata Choudhury, Scott H. Randell, Ewa Krawczyk, Richard Schlegel, Hang Yuan, Tung-Wei Hou, Jie Lu, Frank A. Suprynowicz, Yun-Ling Zheng, Praathibha Sripadhan, Bhaskar Kallakury, Vera Simic, Xuefeng Liu, Chen Chen, Olga A. Timofeeva, Aleksandra Dakic, Dean G. Tang
Publikováno v:
Nature protocols. 12(2)
Historically, it has been difficult to propagate cells in vitro that are derived directly from human tumors or healthy tissue. However, in vitro preclinical models are essential tools for both the study of basic cancer biology and the promotion of tr
Autor:
Ewa Krawczyk, Frank A. Suprynowicz, Sujata Choudhury, Aleksandra Dakic, Richard Schlegel, Nancy Palechor-Ceron, Jie Lu, Vera Simic, Tung-Wei Hou, Hang Yuan, Praathibha Sripadhan, Seema Agarwal, Chen Chen, Xuefeng Liu
Publikováno v:
Cancer Research. 77:5777-5777
The E6/E7 oncogenes of the high-risk HPVs are both necessary and sufficient to immortalize HFKs and their presence and expression is required for the continued proliferation of HPV-positive cervical cancer cells. We and others have shown previously t