Zobrazeno 1 - 10
of 543
pro vyhledávání: '"Tung On Yau"'
Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness
Autor:
Maria Hatziapostolou, Marina Koutsioumpa, Abed M. Zaitoun, Christos Polytarchou, Mouad Edderkaoui, Swapna Mahurkar-Joshi, Jayakumar Vadakekolathu, Daniel D'Andrea, Anna Rose Lay, Niki Christodoulou, Thuy Pham, Tung-On Yau, Christina Vorvis, Suchit Chatterji, Stephen J. Pandol, George A. Poultsides, David W. Dawson, Dileep N. Lobo, Dimitrios Iliopoulos
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 5, Pp 687-702 (2024)
Background and Aims: Decoding pancreatic ductal adenocarcinoma heterogeneity and the consequent therapeutic selection remains a challenge. We aimed to characterize epigenetically regulated pathways involved in pancreatic ductal adenocarcinoma progres
Externí odkaz:
https://doaj.org/article/ed3b70b9de5c43699e1addca71804e12
Autor:
Jia Chang, Guangyou Duan, Wenjing Li, Tung On Yau, Chang Liu, Jianlin Cui, Huaijun Xue, Wenjun Bu, Yanping Hu, Shan Gao
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
BackgroundIdentification of transposons without close homologs is still a difficult task. IS630/Tc1/mariner transposons, classified into a superfamily, are probably the most widespread DNA transposons in nature. Tc1/mariner transposons have been disc
Externí odkaz:
https://doaj.org/article/cbb647a3fc954a188f1dc490f4cebf22
Autor:
Sergio Rutella, Jayakumar Vadakekolathu, Francesco Mazziotta, Stephen Reeder, Tung-On Yau, Rupkatha Mukhopadhyay, Benjamin Dickins, Heidi Altmann, Michael Kramer, Hanna A. Knaus, Bruce R. Blazar, Vedran Radojcic, Joshua F. Zeidner, Andrea Arruda, Bofei Wang, Hussein A. Abbas, Mark D. Minden, Sarah K. Tasian, Martin Bornhäuser, Ivana Gojo, Leo Luznik
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
Background Immune exhaustion and senescence are dominant dysfunctional states of effector T cells and major hurdles for the success of cancer immunotherapy. In the current study, we characterized how acute myeloid leukemia (AML) promotes the generati
Externí odkaz:
https://doaj.org/article/9b9ef0d762ff4c06a07a3be5dd99fa73
Autor:
Jia Chang, Jinlong Bei, Qi Shao, Hemu Wang, Huan Fan, Tung On Yau, Wenjun Bu, Jishou Ruan, Dongsheng Wei, Shan Gao
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundCurrently, methylotrophic yeasts (e.g., Pichia pastoris, Ogataea polymorpha, and Candida boindii) are subjects of intense genomics studies in basic research and industrial applications. In the genus Ogataea, most research is focused on thre
Externí odkaz:
https://doaj.org/article/9622e2fa4c3940bc95936b9279008e07
Autor:
Tung On Yau
Publikováno v:
JGH Open, Vol 3, Iss 5, Pp 361-369 (2019)
Until recently, a one‐drug‐fits‐all model was applied to every patient diagnosed with the same condition. But not every condition is the same, and this has led to many cases of ineffective treatment. Pharmacogenetics is increasingly used to str
Externí odkaz:
https://doaj.org/article/bdc95dfdb3dd436f8ae40877df527fce
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background With the unprecedented rapid growth rate (up to 2.75 cm/day), velvet antler is an invaluable model for the identification of potent growth factors and signaling networks for extremely fast growing tissues, mainly cartilage. Antler
Externí odkaz:
https://doaj.org/article/fe98040238ac40368876ea3328cc193e
Autor:
Xin Li, Jia Chang, Shunmei Chen, Liangge Wang, Tung On Yau, Qiang Zhao, Zhangyong Hong, Jishou Ruan, Guangyou Duan, Shan Gao
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
In December 2019, the world awoke to a new betacoronavirus strain named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Betacoronavirus consists of A, B, C and D subgroups. Both SARS-CoV and SARS-CoV-2 belong to betacoronavirus subgroup
Externí odkaz:
https://doaj.org/article/e0226403b3094f40add9e5f814c38320
Autor:
Tanya M. Monaghan, Niharika A. Duggal, Elisa Rosati, Ruth Griffin, Jamie Hughes, Brandi Roach, David Y. Yang, Christopher Wang, Karen Wong, Lynora Saxinger, Maja Pučić-Baković, Frano Vučković, Filip Klicek, Gordan Lauc, Paddy Tighe, Benjamin H. Mullish, Jesus Miguens Blanco, Julie A. K. McDonald, Julian R. Marchesi, Ning Xue, Tania Dottorini, Animesh Acharjee, Andre Franke, Yingrui Li, Gane Ka-Shu Wong, Christos Polytarchou, Tung On Yau, Niki Christodoulou, Maria Hatziapostolou, Minkun Wang, Lindsey A. Russell, Dina H. Kao
Publikováno v:
Cells, Vol 10, Iss 11, p 3234 (2021)
Fecal microbiota transplantation (FMT) is highly effective in recurrent Clostridioides difficile infection (CDI); increasing evidence supports FMT in severe or fulminant Clostridioides difficile infection (SFCDI). However, the multifactorial mechanis
Externí odkaz:
https://doaj.org/article/7745900c03be42aca7c8715cf0961b52
Autor:
Tanya M. Monaghan, Rima N. Biswas, Rupam R. Nashine, Samidha S. Joshi, Benjamin H. Mullish, Anna M. Seekatz, Jesus Miguens Blanco, Julie A. K. McDonald, Julian R. Marchesi, Tung on Yau, Niki Christodoulou, Maria Hatziapostolou, Maja Pucic-Bakovic, Frano Vuckovic, Filip Klicek, Gordan Lauc, Ning Xue, Tania Dottorini, Shrikant Ambalkar, Ashish Satav, Christos Polytarchou, Animesh Acharjee, Rajpal Singh Kashyap
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1485 (2021)
Background: Non-communicable diseases (NCDs) have become a major cause of morbidity and mortality in India. Perturbation of host–microbiome interactions may be a key mechanism by which lifestyle-related risk factors such as tobacco use, alcohol con
Externí odkaz:
https://doaj.org/article/d6457f3fd58745568d8bb0b3ec6842db
Autor:
Guangcai, Liang, Dong, Mi, Jia, Chang, Tung, On Yau, Guofeng, Xu, Jishou, Ruan, Wenjun, Bu, Shan, Gao
Publikováno v:
Mitochondrion. 65:145-149
In the present study, we performed precise annotation of Drosophila melanogaster, D. simulans, D. grimshawi, Bactrocera oleae mitochondrial (mt) genomes using pan RNA-seq analysis. Using PacBio cDNA-seq data from D. simulans, we precisely annotated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33266f7f452ccc5d6425e8ae3955bd0d
https://doi.org/10.1016/j.mito.2022.06.006
https://doi.org/10.1016/j.mito.2022.06.006