Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tung Ling L Chen"'
Publikováno v:
Plant Physiology. 163:1218-1229
Lipid transfer proteins (LTPs) are small secretory proteins in plants with defined lipid-binding structures for possible lipid exocytosis. Special groups of LTPs unique to the anther tapetum are abundant, but their functions are unclear. We studied a
Publikováno v:
Plant Physiology. 161:1862-1874
In primitive and higher plants, intracellular storage lipid droplets (LDs) of triacylglycerols are stabilized with a surface layer of phospholipids and oleosin. In chlorophytes (green algae), a protein termed major lipid-droplet protein (MLDP) rather
Autor:
Karen J. Colley, Brett E. Close, Barbara M. Vertel, Nyahne Q. Bergeron, Tung Ling L Chen, Tracy J. Bohrer, Chun Chen
Publikováno v:
Glycobiology. 13:109-117
alpha2,6-Sialyltransferase (ST6Gal I) functions in the Golgi to terminally sialylate the N-linked oligosaccharides of glycoproteins. Interestingly, rat ST6Gal I is expressed as two isoforms, STtyr and STcys, that differ by a single amino acid in thei
Autor:
Peiyin Y. Wang, Nina W. Flay, Seung S. Gwon, Wei Luo, Marvin L. Tanzer, Barbara M. Vertel, Tung-Ling L. Chen, Jing Zheng, Chunxia Guo
Publikováno v:
Experimental Cell Research. 263:224-235
In this article, we report the misdirected targeting of expressed aggrecan domains. Aggrecan, the chondroitin sulfate (CS) proteoglycan of cartilage, normally progresses through the exocytic pathway. Proteins expressed from constructs containing the
Publikováno v:
Development. 127:2715-2728
During cell sorting in Dictyostelium, we observed that GFP-tagged prestalk cells (ecmAO-expressing cells) moved independently and directionally to form a cluster. This is consistent with a chemotaxis model for cell sorting (and not differential adhes
Publikováno v:
Journal of Cell Science. 98:159-168
Neomycin has been reported to inhibit polyphosphoinositide cycling by preventing the hydrolysis of phosphatidylinositol 4,5-bisphosphate into inositol 1,4,5-trisphosphate and 1,2-diacylglycerol. Inositol 1,4,5-trisphosphate, through the mobilization
Publikováno v:
Journal of cellular biochemistry. 103(3)
Mutations in cartilage oligomeric matrix protein (COMP) produce clinical phenotypes ranging from the severe end of the spectrum, pseudoachondroplasia (PSACH), which is a dwarfing condition, to a mild condition, multiple epiphyseal dysplasia (MED). Pa
Publikováno v:
The Journal of biological chemistry. 281(41)
The addition of sialic acid to glycoproteins and glycolipids requires Golgi sialyltransferases to have access to their glycoconjugate substrates and nucleotide sugar donor, CMP-sialic acid. CMP-sialic acid is transported into the lumen of the Golgi c
Autor:
Barbara M. Vertel, Anish Shah, Lianwu Fu, Elizabeth Sztul, Tung-Ling L. Chen, Albert Tousson, Ya-sheng Gao
Publikováno v:
Molecular biology of the cell. 16(10)
Nuclear aggregates formed by proteins containing expanded poly-glutamine (poly-Q) tracts have been linked to the pathogenesis of poly-Q neurodegenerative diseases. Here, we show that a protein (GFP170*) lacking poly-Q tracts forms nuclear aggregates
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 23(7)
Pseudoachondroplasia (PSACH) is an autosomal dominant disease that mainly affects cartilage, resulting in skeletal dysplasias and early onset osteoarthritis. PSACH is caused by mutations in the cartilage oligomeric matrix protein (COMP) gene. PSACH c