Zobrazeno 1 - 10
of 568
pro vyhledávání: '"Tung Hu Tsai"'
Autor:
James Mei-Lin Chan, Yuan-Ching Chang, Hua-Chen Chan, Hsiu-Chuan Chan, Wei-Chin Chang, Liu-Fang Wang, Tung-Hu Tsai, Yu-Jen Chen, Wen-Chien Huang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Human malignant pleural mesothelioma (hMPM) is an aggressive, rare disease with a poor prognosis. Histologically, MPM is categorized into epithelioid, biphasic, and sarcomatoid subtypes, with the epithelioid subtype generally displaying a be
Externí odkaz:
https://doaj.org/article/3de7829d7ba14934a8a64cf707823b20
Autor:
Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Ling Yang, Tung-Yi Lin, Muh-Hwa Yang, Tung-Hu Tsai
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-7 (2023)
Abstract Background The antiviral drug molnupiravir is an orally bioavailable prodrug of the nucleoside analog β-D-N4-hydroxycytidine (NHC), which is used to treat coronavirus disease 2019 (COVID-19). However, there is very little information on the
Externí odkaz:
https://doaj.org/article/4083a271a48c4439baf9c131e32988e1
Autor:
Wen-Kuei Chang, Yen-Ting Chen, Chin-Ping Lin, Chia-Jung Wang, Hui-Ru Shieh, Chih-Wen Chi, Tung-Hu Tsai, Yu-Jen Chen
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1568 (2024)
Colon cancer has a poor clinical response to anti-PD1 therapy. This study aimed to evaluate the effect of cordycepin on the efficacy of anti-PD1 treatment in colon cancer. The viability of CT26 mouse colon carcinoma cells, cell-cycle progression, mor
Externí odkaz:
https://doaj.org/article/d901e0ef50c84ff498fb5812e2beae33
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24333- (2024)
Background: Ritonavir is one of the most potent CYP3A4 inhibitor currently on the market, and is often used together with other antiviral drugs to increase their bioavailability and efficacy. Paxlovid, consisting of nirmatrelvir and ritonavir, was ap
Externí odkaz:
https://doaj.org/article/a7e69b23ca7b44748bcef709995ba261
Autor:
Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Tung-Yi Lin, Muh-Hwa Yang, Jeffrey W. Dalley, Tung-Hu Tsai
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104748- (2023)
Summary: Background: Molnupiravir is an orally bioavailable prodrug of the nucleoside analogue β-D-N4-hydroxycytidine (NHC) and is used to treat coronavirus disease 2019 (COVID-19). However, the pharmacokinetics and transplacental transfer of molnup
Externí odkaz:
https://doaj.org/article/ea27156d271348a2a78f0ff4a9a7ce97
Autor:
Tun-Pin Hsueh, Tung-Hu Tsai
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Renal sodium retention is an essential indicator that is used for the prognosis of cirrhosis with ascites that requires diuretic treatment to restore sodium homeostasis. The diuretic effects of Yin-Chen-Hao-Tang (YCHT) alone or in combination with di
Externí odkaz:
https://doaj.org/article/7684b5d2253549c9a2e1ce9cf4a52489
Autor:
Ling Yang, Tung-Hu Tsai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113938- (2022)
Valproic acid (VPA) is a widely used antiepileptic drug, and the herbal extract of Gastrodia elata exerts an anticonvulsant effect. However, few studies have investigated the pharmacokinetic and pharmacodynamic interactions between G. elata extract a
Externí odkaz:
https://doaj.org/article/d9efe5d491dc4d3a964a653de980803a
Autor:
Jung-Hung Chen, I-Hsin Lin, Chung-Kai Sun, Ling Yang, Thomas Y. Hsueh, Chin-Tsung Ting, Tung-Hu Tsai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113613- (2022)
Acetaminophen is among the most widely used analgesics; however, the proportion and mechanism of transplacental transfer of unbound acetaminophen with actual pharmacological activity remain unknown. Our hypothesis is that acetaminophen gradually pene
Externí odkaz:
https://doaj.org/article/11eba6676dd147e5a13e2ffae8da3924
Publikováno v:
ACS Omega, Vol 6, Iss 24, Pp 15804-15815 (2021)
Externí odkaz:
https://doaj.org/article/2a5ff6d447114e2490de7c4bb0403349
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104095- (2022)
Summary: Background: Remdesivir was the first prodrug approved to treat coronavirus disease 2019 (COVID-19) and has the potential to be used during pregnancy. However, it is not known whether remdesivir and its main metabolite, GS-441524 have the pot
Externí odkaz:
https://doaj.org/article/ac67bae12fc34227aafe4f6595334ef8