The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells' Ubiquitylome.

Autor: Tundo GR; Department of Clinical Sciences and Translational Medicine, University of Tor Vergata, 00133 Rome, Italy., Cavaterra D; Department of Chemical Sciences and Technologies, University of Tor Vergata, 00133 Rome, Italy., Pandino I; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Zingale GA; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Giammaria S; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Boccaccini A; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Michelessi M; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Roberti G; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Tanga L; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Carnevale C; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Figus M; Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, 56124 Pisa, Italy., Grasso G; Department of Chemical Sciences, University of Catania, 95125 Catania, Italy., Coletta M; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Bocedi A; Department of Chemical Sciences and Technologies, University of Tor Vergata, 00133 Rome, Italy., Oddone F; IRCCS-Fondazione Bietti, 00168 Rome, Italy., Sbardella D; IRCCS-Fondazione Bietti, 00168 Rome, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 17; Vol. 25 (18). Date of Electronic Publication: 2024 Sep 17.

Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

Autor: Benvenuto, M, Angiolini, V, Focaccetti, C, Nardozi, D, Palumbo, C, Carrano, R, Rufini, A, Bei, R, Miele, Mt, Mancini, P, Barillari, G, Cirone, M, Ferretti, E, Tundo, Gr, Mutti, L, Masuelli, L

Publikováno v: Biology Direct. 18

Background Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis. The low efficacy of current treatment options highlights the urge to identify more effective therapies aimed at improving MM patients’ survival. Bortezomib (Bor) is a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754f5e55ea7b4ea9e9abeba4b4be2ed0
https://doi.org/10.1186/s13062-023-00374-w

The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design.

Autor: Tundo GR; Department of Clinical Science and Traslational Medicine, University of Rome Tor Vergata, Via Della Ricerca Scientifica 1, 00133 Rome, Italy., Grasso G; Department of Chemical Sciences, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy., Persico M; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy., Tkachuk O; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy., Bellia F; Institute of Crystallography, CNR, Via Paolo Gaifami 18, 95126 Catania, Italy., Bocedi A; Department of Chemical Sciences and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome, Italy., Marini S; Department of Clinical Science and Traslational Medicine, University of Rome Tor Vergata, Via Della Ricerca Scientifica 1, 00133 Rome, Italy., Parravano M; IRCCS-Fondazione Bietti, Rome, Italy., Graziani G; Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy., Fattorusso C; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy., Sbardella D; IRCCS-Fondazione Bietti, Rome, Italy.

Publikováno v: Biomolecules [Biomolecules] 2023 Oct 07; Vol. 13 (10). Date of Electronic Publication: 2023 Oct 07.

Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study.

Autor: De Simone G; Dipartimento di Scienze, Università Roma Tre, 00146 Roma, Italy., di Masi A; Dipartimento di Scienze, Università Roma Tre, 00146 Roma, Italy., Tundo GR; Dipartimento di Scienze Cliniche e Medicina Traslazionale, Università di Roma Tor Vergata, 00133 Roma, Italy., Coletta M; IRCCS Fondazione Bietti, 00198 Roma, Italy., Ascenzi P; Laboratorio Interdipartimentale di Microscopia Elettronica, Università Roma Tre, 00146 Roma, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 31; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 31.

Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813].

Autor: Persico M; Department of Pharmacy, Università di Napoli 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy., García-Viñuales S; Consiglio Nazionale delle Ricerche, Istituto di Cristallografia, Sede Secondaria di Catania, Via Paolo Gaifami 18, 95126 Catania, Italy., Santoro AM; Consiglio Nazionale delle Ricerche, Istituto di Cristallografia, Sede Secondaria di Catania, Via Paolo Gaifami 18, 95126 Catania, Italy., Lanza V; Consiglio Nazionale delle Ricerche, Istituto di Cristallografia, Sede Secondaria di Catania, Via Paolo Gaifami 18, 95126 Catania, Italy., Tundo GR; IRCSS-Fondazione GB Bietti, 00198 Roma, Italy., Sbardella D; IRCSS-Fondazione GB Bietti, 00198 Roma, Italy., Coletta M; IRCSS-Fondazione GB Bietti, 00198 Roma, Italy., Romanucci V; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, I-80126 Napoli, Italy., Zarrelli A; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, I-80126 Napoli, Italy., Di Fabio G; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, I-80126 Napoli, Italy., Fattorusso C; Department of Pharmacy, Università di Napoli 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy. Electronic address: caterina.fattorusso@unina.it., Milardi D; Consiglio Nazionale delle Ricerche, Istituto di Cristallografia, Sede Secondaria di Catania, Via Paolo Gaifami 18, 95126 Catania, Italy. Electronic address: danilo.milardi@cnr.it.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Sep 01; Vol. 69, pp. 116895. Date of Electronic Publication: 2022 Jun 24.