Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tuna Guengoer"'
Autor:
Jens Popken, Alexander Graf, Stefan Krebs, Helmut Blum, Volker J Schmid, Axel Strauss, Tuna Guengoer, Valeri Zakhartchenko, Eckhard Wolf, Thomas Cremer
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124619 (2015)
The present study demonstrates a major remodeling of the nuclear envelope and its underlying lamina during bovine preimplantation development. Up to the onset of major embryonic genome activation (MGA) at the 8-cell stage nuclei showed a non-uniform
Externí odkaz:
https://doaj.org/article/4fbc0a0eb0434c29949c58f6be5f1d1a
Autor:
Valeri Zakhartchenko, Alexander Graf, Daniela Koehler, A. Wuensch, Tuna Guengoer, Eckhard Wolf, Alessandro Brero, Volker Schmid, Thomas Cremer, Helmut Blum, Jens Popken, Stefan Krebs, Axel Strauss
Publikováno v:
Nucleus
Nuclear landscapes were studied during preimplantation development of bovine embryos, generated either by in vitro fertilization (IVF), or generated as cloned embryos by somatic cell nuclear transfer (SCNT) of bovine fetal fibroblasts, using 3-dimens
Autor:
Alessandro Brero, A. Wuensch, Tobias Thormeyer, Thomas Cremer, Valeri Zakhartchenko, Daniela Koehler, Tuna Guengoer, Eckhard Wolf, Jens Popken
Publikováno v:
Nucleus
Cloned bovine preimplantation embryos were generated by somatic cell nuclear transfer (SCNT) of bovine fetal fibroblasts with a silent copy of the pluripotency reporter gene GOF, integrated at a single site of a chromosome 13. GOF combines the regula
Autor:
Fred Sinowatz, Andreas Hofmann, Alexander Pfeifer, M. Reichenbach, Holm Zerbe, Tuna Guengoer, Marieke Matthiesen, Frank Weber, Tiongti Lim, T. Grupp, Eckhard Wolf, Felix A. Habermann, Horst-Dieter Reichenbach
Publikováno v:
Transgenic Research. 19:549-556
Lentiviral vectors are a powerful tool for the genetic modification of livestock species. We previously generated transgenic founder cattle with lentiviral integrants carrying enhanced green fluorescent protein (EGFP) under the control of the phospho
Publikováno v:
The Journal of Reproduction and Development
Utilizing 3D structured illumination microscopy, we investigated the quality and quantity of nuclear invaginations and the distribution of nuclear pores during rabbit early embryonic development and identified the exact time point of nucleoporin 153
Publikováno v:
BMC Developmental Biology
Background Super-resolution fluorescence microscopy performed via 3D structured illumination microscopy (3D-SIM) is well established on flat, adherent cells. However, blastomeres of mammalian embryos are non-adherent, round and large. Scanning whole
Autor:
Stefan Krebs, Tuna Guengoer, Alexander Graf, Eckhard Wolf, Axel Strauss, Thomas Cremer, Volker Schmid, Helmut Blum, Valeri Zakhartchenko, Jens Popken
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0124619 (2015)
PLoS ONE, Vol 10, Iss 5, p e0124619 (2015)
The present study demonstrates a major remodeling of the nuclear envelope and its underlying lamina during bovine preimplantation development. Up to the onset of major embryonic genome activation (MGA) at the 8-cell stage nuclei showed a non-uniform
Autor:
Jens Popken, E. Oztas, Meral Baka, Tuna Guengoer, Özlem Yilmaz, Yiğit Uyanıkgil, Valeri Zakhartchenko, Türker Çavuşoğlu, Utku Ateş
Publikováno v:
Europe PubMed Central
Cryopreservation is the process of freezing and preserving cells and tissues at low temperatures. Controlled slow freezing and vitrification have successfully been used for cryopreservation of mammalian embryos. We investigated the effect of these tw
Autor:
Tuna Guengoer, Helmut Blum, V. Zakhartchenko, Stefan Krebs, Thomas Cremer, E. Wolf, Alexander Graf, Jens Popken
Publikováno v:
Reproduction, Fertility and Development. 27:134
In the present study, we investigated the changes of the nuclear envelope and its underlying lamina, as well as features of higher order chromatin organisation in bovine embryos generated by in vitro fertilization during pre-implantation development.
Autor:
Tuna Guengoer, Jens Popken, Valeri Zakhartchenko, Eckhard Wolf, Axel Strauss, Maik Dahlhoff, Volker Schmid, Thomas Cremer
Publikováno v:
Reproduction, Fertility and Development. 27:139
Nuclear invaginations carrying nuclear pores may facilitate increased mRNA export and protein import to areas inside the nucleus remote from the nuclear border. In this study on rabbit embryos, we investigated whether large early embryonic nuclei and