Zobrazeno 1 - 10
of 1 165
pro vyhledávání: '"Tumour progression"'
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 09, Pp 22-26 (2024)
Introduction: During the Epithelial-mesenchymal Transition (EMT) process, cells undergo a transformation in which they lose their epithelial characteristics and acquire mesenchymal traits. This phenomenon was observed during the metastatic stage of n
Externí odkaz:
https://doaj.org/article/2b5efbf333c14626ad64c31cec21d048
Autor:
Sophie Pirenne, Fátima Manzano-Núñez, Axelle Loriot, Sabine Cordi, Lieven Desmet, Selda Aydin, Catherine Hubert, Sébastien Toffoli, Nisha Limaye, Christine Sempoux, Mina Komuta, Laurent Gatto, Frédéric P. Lemaigre
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Most studies on tumour progression from precursor lesion toward gallbladder adenocarcinoma investigate lesions sampled from distinct patients, providing an overarching view of pathogenic cascades. Whether this reflects the tumouri
Externí odkaz:
https://doaj.org/article/888ee42661c44f70b730f4a7d0dccaca
Autor:
Dániel Sztankovics, Fatime Szalai, Dorottya Moldvai, Titanilla Dankó, Noémi Nagy, Judit Pápay, András Khoór, Ildikó Krencz, Anna Sebestyén
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 4, Pp 151468- (2024)
Small cell lung carcinoma (SCLC) is a highly malignant cancer with early metastatic dissemination and poor clinical outcomes. Mutations in the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway, i
Externí odkaz:
https://doaj.org/article/330b1db415774fd19967c36c4c2a7cae
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Steroid receptor coactivator-1 (SRC-1, also known as NCOA1) frequently functions as a transcriptional coactivator by directly binding to transcription factors and recruiting to the target gene promoters to promote gene transcription by incre
Externí odkaz:
https://doaj.org/article/ada114a6616f4d3c8ca3b5ca8303b817
Autor:
Xinyi Ma, Zhenhua Chen, Wei Chen, Ziyuan Chen, Yue Shang, Yikai Zhao, Leyi Li, Chengwei Zhou, Jinxian He, Xiaodan Meng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Extracellular vesicles (EVs) participate in cancer development via cell-to-cell communication. Long non-coding RNAs (lncRNAs), one component of EVs, can play an essential role in non-small-cell lung cancer (NSCLC) through EV-media
Externí odkaz:
https://doaj.org/article/d26ebc5853734eea8cdd9822d33cb2d3
Autor:
Jianqun Wang, Mei Hong, Yang Cheng, Xiaojing Wang, Dan Li, Guo Chen, Banghe Bao, Jiyu Song, Xinyi Du, Chunhui Yang, Liduan Zheng, Qiangsong Tong
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background A series of studies have demonstrated the emerging involvement of transfer RNA (tRNA) processing during the progression of tumours. Nevertheless, the roles and regulating mechanisms of tRNA processing genes in neuroblastoma (NB),
Externí odkaz:
https://doaj.org/article/4880a7c8cd36489c9cd2b334a707629d
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30654- (2024)
Angiogenin (ANG) is a specialised secreted ribonuclease, also known as RNase5, that is widely expressed in vertebrates. ANG dysregulation is closely associated with the development of breast, nasopharyngeal, and lung cancers. In recent years, studies
Externí odkaz:
https://doaj.org/article/0e4c212878be414bbf6613b1e7f3d744
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 223-234 (2023)
The tricarboxylic acid (TCA) cycle is a central route for generating cellular energy and precursors for biosynthetic pathways. Emerging evidences have shown that the aberrations of metabolic enzymes which affect the integrity of TCA cycle are implica
Externí odkaz:
https://doaj.org/article/39abc19c0537400381820cb6d6a31160
Autor:
Zeli Yin, Liming Wang
Publikováno v:
Annals of Medicine, Vol 55, Iss 1, Pp 1058-1069 (2023)
AbstractTumour-associated endothelial cells (TECs) are a critical stromal cell type in the tumour microenvironment and play central roles in tumour angiogenesis. Notably, TECs have phenotypic plasticity, as they have the potential to transdifferentia
Externí odkaz:
https://doaj.org/article/e9aa2ac6a6c64368a587bd1601cac218
Publikováno v:
BMC Medical Imaging, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background To investigate the diagnostic performance of parameters derived from monoexponential, biexponential, and stretched-exponential diffusion-weighted imaging models in differentiating tumour progression from pseudoprogression in gliob
Externí odkaz:
https://doaj.org/article/ddcb09898c444511a0126758944bd0b8