Zobrazeno 1 - 10
of 5 182
pro vyhledávání: '"Tumour microenvironment"'
Autor:
Ana Paula Vargas Garcia, Luana Aparecida Reis, Bárbara Regina Melo Ribeiro, Cristiana Buzelin Nunes, Ana Maria de Paula, Geovanni Dantas Cassali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract New diagnostic and therapeutic approaches have been increasingly demanded due to the high morbidity and mortality associated with breast cancer. Recently, changes in the collagen fibres in mammary neoplasms have been shown to provide informa
Externí odkaz:
https://doaj.org/article/f9513168a1364ec7aac6e213a1e26205
Autor:
Xiang Wang, Bei Feng, Hai-Ying Guo, Fei-Fei Yao, Hui-Nan Song, Xi-Yue Wang, Xiao-Chen Sun, Kai Wang, Yu-Chen Ge, Rui Cui
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Increasing evidence suggests a link between the enzyme cathepsin S (CTSS) and tumour development. However, the potential involvement and molecular functions of CTSS in clear cell renal cell carcinoma (ccRCC) remain unclear. Method
Externí odkaz:
https://doaj.org/article/d32dd82179c1421a9afcc984fbbb3d19
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Uveal melanoma (UM) is a rare aggressive intraocular tumour that spreads most commonly to the liver in tumours with loss of one copy of chromosome 3 (HR-M3); current treatments for metastatic disease remain largely ineffective. Pre-clinical
Externí odkaz:
https://doaj.org/article/d102b717b0814e5f85c61bc4532fd65f
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-23 (2024)
Abstract Background Abnormal sphingolipid metabolism (SM) is closely linked to the incidence of cancers. However, the role of SM in pancreatic cancer (PC) remains unclear. This study aims to explore the significance of SM in the prognosis, immune mic
Externí odkaz:
https://doaj.org/article/090d7c10a95a43cebb5edd5049bf7a5f
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Purposes T cells play a crucial role as regulators of anti-tumor activity within the tumor microenvironment (TME) and are closely associated with the progression of osteosarcoma (OS). Nevertheless, the specific role of T cell-related genes (
Externí odkaz:
https://doaj.org/article/9fbe3966933d4bf0b8724160d6dfd37c
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Metabolic rewiring of cancer cells is one of the hallmarks of cancer. As a consequence, the metabolic landscape of the tumour microenvironment (TME) differs compared to correspondent healthy tissues. Indeed, due to the accumulation of acid m
Externí odkaz:
https://doaj.org/article/4af1616db50a4c1a873ab4c17cd5d14a
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract The tumour microenvironment represents a novel frontier in oncological research. Over the past decade, accumulating evidence has underscored the importance of the tumour microenvironment (TME), including tumour cells, stromal cells, immune c
Externí odkaz:
https://doaj.org/article/f42347b6d51345c1a524356cd0bbf518
Autor:
Inken Flörkemeier, Lisa K. Antons, Jörg P. Weimer, Nina Hedemann, Christoph Rogmans, Sandra Krüger, Regina Scherließ, Astrid Dempfle, Norbert Arnold, Nicolai Maass, Dirk O. Bauerschlag
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract In vitro, spheroid models have become well established in cancer research because they can better mimic certain characteristics of in vivo tumours. However, interaction with the tumour microenvironment, such as cancer-associated fibroblasts,
Externí odkaz:
https://doaj.org/article/64babe67f1b14d97a499efdf4b30fa15
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Purpose The aim of this study is to delve into the value of N6-Methyladenosine (m6A)-associated genes (MAGs) in pancreatic cancer (PC) prognosis. Methods PC sequencing data and corresponding clinicopathological information were retrieved fro
Externí odkaz:
https://doaj.org/article/2637f991f5a44eb3986e6afdaa83184e
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-25 (2024)
Abstract Platelets are a significant component of the cell population in the tumour microenvironment (TME). Platelets influence other immune cells and perform cross-talk with tumour cells, playing an important role in tumour development. Extracellula
Externí odkaz:
https://doaj.org/article/6f8ab7f132404e24a7b2bd0c81bf411b