Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Tumour evolution"'
Autor:
Sandra Brosda, Lauren G. Aoude, Vanessa F. Bonazzi, Kalpana Patel, James M. Lonie, Clemence J. Belle, Felicity Newell, Lambros T. Koufariotis, Venkateswar Addala, Marjan M. Naeini, AGITG DOCTOR Investigators, John V. Pearson, Lutz Krause, Nicola Waddell, Andrew P. Barbour
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Oesophageal adenocarcinoma (OAC) is a highly heterogeneous cancer with poor survival. Standard curative treatment is chemotherapy with or without radiotherapy followed by oesophagectomy. Genomic heterogeneity is a feature of OAC a
Externí odkaz:
https://doaj.org/article/43ba55869131407abd9450bd4e269118
Autor:
Serena Mazzucchelli, Lorena Signati, Letizia Messa, Alma Franceschini, Arianna Bonizzi, Lorenzo Castagnoli, Patrizia Gasparini, Clarissa Consolandi, Eleonora Mangano, Paride Pelucchi, Ingrid Cifola, Tania Camboni, Marco Severgnini, Laura Villani, Barbara Tagliaferri, Stephana Carelli, Serenella M. Pupa, Cristina Cereda, Fabio Corsi
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background A reliable preclinical model of patient-derived organoids (PDOs) was developed in a case study of a 69-year-old woman diagnosed with breast cancer (BC) to investigate the tumour evolution before and after neoadjuvant chemotherapy
Externí odkaz:
https://doaj.org/article/87a0c667c3c14d669d41b5cdc4ebd64b
Autor:
Grace Y. Q. Han, Monica Alexander, Julia Gattozzi, Marilyn Day, Elayna Kirsch, Narges Tafreshi, Raafat Chalar, Soraya Rahni, Gabrielle Gossner, William Burke, Mehdi Damaghi
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Ovarian cancer ecosystems are exceedingly complex, consisting of a high heterogeneity of cancer cells. Development of drugs such as poly ADP‐ribose polymerase (PARP) inhibitors, targeted therapies and immunotherapies offer more options for
Externí odkaz:
https://doaj.org/article/15483453998c433487c94769a739a3a3
Autor:
Zeng, Peter Y.F. 1, 2, 3, 4, 47, Prokopec, Stephenie D. 5, 45, 46, 47, Lai, Stephen Y. 6, 47, Pinto, Nicole 1, Chan-Seng-Yue, Michelle A. 5, Clifton-Bligh, Roderick 7, Williams, Michelle D. 8, Howlett, Christopher J. 9, Plantinga, Paul 9, Cecchini, Matthew J. 10, Lam, Alfred K. 10, Siddiqui, Iram 11, Wang, Jianxin 5, Sun, Ren X. 5, Watson, John D. 5, 45, 46, Korah, Reju 12, Carling, Tobias 12, Agrawal, Nishant 13, Cipriani, Nicole 14, Ball, Douglas 15, Nelkin, Barry 16, Rooper, Lisa M. 17, Bishop, Justin A. 18, Garnis, Cathie 19, Berean, Ken 19, Nicolson, Norman G. 12, Weinberger, Paul 20, 21, Henderson, Ying C. 6, Lalansingh, Christopher M. 5, Tian, Mao 45, 46, Yamaguchi, Takafumi N. 5, 45, 46, Livingstone, Julie 5, 45, 46, Salcedo, Adriana 5, 22, 42, Patel, Krupal 1, 5, Vizeacoumar, Frederick 23, Datti, Alessandro 24, 25, Xi, Liu 26, Nikiforov, Yuri E. 27, Smallridge, Robert 28, Copland, John A. 29, Marlow, Laura A. 29, Hyrcza, Martin D. 30, Delbridge, Leigh 31, 32, Sidhu, Stan 31, 32, Sywak, Mark 31, 32, Robinson, Bruce 32, 33, Fung, Kevin 1, 4, Ghasemi, Farhad 1, Kwan, Keith 9, MacNeil, S. Danielle 1, 4, Mendez, Adrian 1, 4, Palma, David A. 2, 3, 4, Khan, Mohammed I. 1, Shaikh, Mushfiq 1, Ruicci, Kara M. 1, Wehrli, Bret 9, Winquist, Eric 2, 3, 4, Yoo, John 1, 4, Mymryk, Joe S. 1, 2, 4, 34, Rocco, James W. 35, Wheeler, David 26, Scherer, Steve 26, Giordano, Thomas J. 36, Barrett, John W. 1, Faquin, William C. 37, Gill, Anthony J. 32, 38, 39, Clayman, Gary 40, 47, Boutros, Paul C. 22, 41, 42, 43, 44, 45, 46, 47, ∗, Nichols, Anthony C. 1, 2, 3, 4, 47, 48, ∗∗
Publikováno v:
In Cell Reports 26 March 2024 43(3)
Autor:
Ariana Huebner, James R. M. Black, Francesca Sarno, Roberto Pazo, Ignacio Juez, Laura Medina, Rocio Garcia-Carbonero, Carmen Guillén, Jaime Feliú, Carolina Alonso, Carlota Arenillas, Ana Belén Moreno-Cárdenas, Helena Verdaguer, Teresa Macarulla, Manuel Hidalgo, Nicholas McGranahan, Rodrigo A. Toledo
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Liquid biopsies and the dynamic tracking of somatic mutations within circulating tumour DNA (ctDNA) can provide insight into the dynamics of cancer evolution and the intra-tumour heterogeneity that fuels treatment resistance. Howe
Externí odkaz:
https://doaj.org/article/21716a2b02ec46eb8dbe1a817c4a0bab
Autor:
Hessey, Sonya 1, 2, 3, Fessas, Petros 2, Zaccaria, Simone 1, 3, Jamal-Hanjani, Mariam 1, 2, 4, 6, ⁎, Swanton, Charles 1, 4, 5, 6, ⁎
Publikováno v:
In Trends in Cancer June 2023 9(6):490-502
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Cancer development is an evolutionary process. A key selection pressure is exerted by therapy, one of the few players in cancer evolution that can be controlled. As such, an understanding of how treatment acts to sculpt the tumour and its mi
Externí odkaz:
https://doaj.org/article/2b0afa506c4d46b3a376ebc5cbd3d3e4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Pettres, Roberto a, b, ⁎
Publikováno v:
In Engineering Analysis with Boundary Elements January 2021 122:214-231