Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Tumour antigen"'
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104963- (2024)
Summary: Glioblastoma (GBM) is one of the most lethal central nervous systems (CNS) tumours in adults. As supplements to standard of care (SOC), various immunotherapies improve the therapeutic effect in other cancers. Among them, tumour vaccines can
Externí odkaz:
https://doaj.org/article/f9e1c717f2e74d06b92da6fd603d9773
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Background Dendritic cells (DCs) mediate divergent immune effects by activating T cells or negatively regulating the immune response to promote immune tolerance. They perform specific functions determined by their tissue distribution and mat
Externí odkaz:
https://doaj.org/article/bdec72febe214cdcbc0ef7c7dd41d275
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
The processing of endogenous tumour antigen peptides was essential for anti-tumour immunity in the tumour microenvironment. A high degree of Endogenous tumour antigen peptide processing has been demonstrated to improve the prognosis of carcinoma pati
Externí odkaz:
https://doaj.org/article/1774c3aea2394fb08d9a7192f22a528d
Autor:
Zhan Zhou, Xingzheng Lyu, Jingcheng Wu, Xiaoyue Yang, Shanshan Wu, Jie Zhou, Xun Gu, Zhixi Su, Shuqing Chen
Publikováno v:
Royal Society Open Science, Vol 4, Iss 4 (2017)
Tumour antigens have attracted much attention because of their importance to cancer diagnosis, prognosis and targeted therapy. With the development of cancer genomics, the identification of tumour-specific neoantigens became possible, which is a cruc
Externí odkaz:
https://doaj.org/article/392d6237f7294e1d9fcfdad14a30782b
Autor:
Christian Ottensmeier, Megan Bowers, Debbie Hamid, Tom Maishman, Scott Regan, Wendy Wood, Angelica Cazaly, Louise Stanton
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 3, Iss 3 (2016)
Background: In the UK almost 7000 people are diagnosed with leukaemia each year, but despite continuing advances in diagnosis and treatment with new drugs, such as the tyrosine kinase inhibitors, the majority of these patients will eventually die fro
Externí odkaz:
https://doaj.org/article/be2d7043717143ab8ebd04f4f6f78058
Akademický článek
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Publikováno v:
Journal of Microencapsulation. 37:14-28
Aim: MUC-1 lipopeptide vaccine exhibited immense potential in the treatment of non-small cell lung cancer (NSCLC) in both preclinical and clinical trials. However, it lacks triggering of mucosal im...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa6fb6d06ffc48d3ca47bf4f51ccc39f
https://doi.org/10.1080/02652048.2019.1692943
https://doi.org/10.1080/02652048.2019.1692943
Publikováno v:
British Journal of Dermatology. 180:1302-1311
Background Human polyomaviruses (HPyVs) are small, nonenveloped, double-stranded DNA viruses that express tumour antigen proteins. Fourteen species of polyomaviruses have been discovered in humans, and since the 2008 discovery of the first cutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208800152f262d59689aae2cb5e1cdd2
https://doi.org/10.1111/bjd.17592
https://doi.org/10.1111/bjd.17592
Akademický článek
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Autor:
Antonio Federico, Beatriz Martins, Manlio Fusciello, Mikaela Grönholm, Satu Koskela, Jukka Partanen, Markus Haapala, Erkko Ylösmäki, Dario Greco, Tuija Kekarainen, Tiina Sikanen, Gabriella Antignani, Antti Rannikko, Firas Hamdan, Seppo Ylä-Herttuala, Karita Peltonen, Olga L. Gurvich, Sari Tähkä, Sara Feola, Rui M. M. Branca, Janne Lehtiö, Jacopo Chiaro, Vilja Pietiäinen, Vincenzo Cerullo, Cristian Capasso, Masoumeh Eshaghi, Michaela Feodoroff
Identification of HLA class I ligands from the tumour surface (ligandome or immunopeptidome) is essential for designing T-cell mediated cancer therapeutic approaches. However, the sensitivity of the process for isolating MHC-I restricted tumor-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ad3c2f2bf97051bde61da31211dac0
https://doi.org/10.21203/rs.3.rs-156531/v1
https://doi.org/10.21203/rs.3.rs-156531/v1
