Zobrazeno 1 - 10
of 1 693
pro vyhledávání: '"Tumor-infiltrating lymphocyte"'
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Background Within the tumor microenvironment, altered lipid metabolism promotes cancer cell malignancy by activating oncogenic cascades; however, impact of lipid metabolism in CD4+ tumor-infiltrating lymphocytes (TILs) remains poorly underst
Externí odkaz:
https://doaj.org/article/5c470a24708949918e126c8e65b3fda8
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Tumor-infiltrating lymphocyte (TIL) therapy in adoptive T-cell therapy (ACT) has already caused durable regression in a variety of cancer types due to T-cell persistence, clinical activity, and duration of objective response and safety. TILs
Externí odkaz:
https://doaj.org/article/9ea2ea92a91e4eacbebc1cd27cde25f4
Autor:
Xinyue Liu, Yan Kong, Youwen Qian, Haoyue Guo, Lishu Zhao, Hao Wang, Kandi Xu, Li Ye, Yujin Liu, Hui Lu, Yayi He
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102143- (2024)
Tumor-infiltrating lymphocytes (TILs) are essential components of the tumor microenvironment (TME) of non-small cell lung cancer (NSCLC). Still, it is difficult to describe due to their heterogeneity. In this study, five cell markers from NSCLC patie
Externí odkaz:
https://doaj.org/article/ceebaaa32b9e4abf9a59a22ef910c20f
Autor:
Jing Guo, Chunyan Wang, Ning Luo, Yuliang Wu, Wei Huang, Jihui Zhu, Weihui Shi, Jinye Ding, Yao Ge, Chunhong Liu, Zhen Lu, Robert C. Bast, Guihai Ai, Weihong Yang, Rui Wang, Caixia Li, Rong Chen, Shupeng Liu, Huajun Jin, Binghui Zhao, Zhongping Cheng
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinical and clinical studie
Externí odkaz:
https://doaj.org/article/47172d00ce154c1d97952eab624ecce7
Autor:
Thomas Morgan Hulen, Christina Friese, Nikolaj Pagh Kristensen, Joachim Stoltenborg Granhøj, Troels Holz Borch, Marlies J. W. Peeters, Marco Donia, Mads Hald Andersen, Sine Reker Hadrup, Inge Marie Svane, Özcan Met
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ef1231a8b35045258c3dac4c45de3bd2
Autor:
Deyong Kang, Chuan Wang, Zhonghua Han, Liqin Zheng, Wenhui Guo, Fangmeng Fu, Lida Qiu, Xiahui Han, Jiajia He, Lianhuang Li, Jianxin Chen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The histological grade is an important factor in the prognosis of invasive breast cancer and is vital to accurately identify the histological grade and reclassify of Grade2 status in breast cancer patients. Methods In this study,
Externí odkaz:
https://doaj.org/article/07583ab960ae4fd79682f8b0a42abe84
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundAurora kinase A (AURKA) and tumor-infiltrating lymphocytes (TILs) are both known to play an essential role in tumorigenesis. However, the expression and prognostic value of the AURKA and TILs in medullary thyroid carcinoma (MTC) have not ye
Externí odkaz:
https://doaj.org/article/a576e9c3c4114f15941d8af360f93c2b
Autor:
Joseph Zenga, Musaddiq Awan, Anne Frei, Jamie Foeckler, Rachel Kuehn, Oscar Villareal Espinosa, Jennifer Bruening, Becky Massey, Stuart Wong, Aditya Shreenivas, Monica Shukla, Julia Kasprzak, Yunguang Sun, Md Shaheduzzaman, Fanghong Chen, Tyce Kearl, Heather A. Himburg
Publikováno v:
Translational Oncology, Vol 42, Iss , Pp 101899- (2024)
Background: Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) remains a treatment-resistance disease with limited response to immunotherapy. While T cells in HNSCC are known to display phenotypic dysfunction, whether t
Externí odkaz:
https://doaj.org/article/17155342d9804d488549332997db6abf
Autor:
Hayato TAKEUCHI, Tohru INABA, Yukiko SHISHIDO-HARA, Taku TSUKAMOTO, Shinsuke MIZUTANI, Takanari OKAMOTO, Seisuke TANIGAWA, Takumi YAMANAKA, Yoshinobu TAKAHASHI, Eiichi KONISHI, Junya KURODA, Naoya HASHIMOTO
Publikováno v:
Neurologia Medico-Chirurgica, Vol 63, Iss 11, Pp 495-502 (2023)
Primary central nervous system lymphoma (PCNSL), a relatively rare brain tumor, bears a dire prognosis. On occasion, the rapid progression of the tumor makes immediate diagnosis and initiation of therapy imperative. To achieve swift diagnosis, we ado
Externí odkaz:
https://doaj.org/article/7ffb17d878e942d88c78a0a02dafcf42
Autor:
Dong Hyun Kim, Yoojoo Lim, Sukjun Kim, Chan‐Young Ock, Jeonghwan Youk, Miso Kim, Tae Min Kim, Dong‐Wan Kim, Hak Jae Kim, Jiwon Koh, Kyeong Cheon Jung, Kwon Joong Na, Chang Hyun Kang, Bhumsuk Keam
Publikováno v:
Thoracic Cancer, Vol 14, Iss 30, Pp 3001-3011 (2023)
Abstract Background Thymic epithelial tumors (TET) are rare malignancies and lack well‐defined biomarkers for neoadjuvant therapy. This study aimed to evaluate the clinical utility of artificial intelligence (AI)‐powered tumor‐infiltrating lymp
Externí odkaz:
https://doaj.org/article/5e44aea6aa9e432da4bc8eedf2075dee