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pro vyhledávání: '"Tumor protection"'
Akademický článek
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Autor:
Kenneth Lundstrom
Publikováno v:
Viruses, Vol 6, Iss 6, Pp 2392-2415 (2014)
Alphavirus vectors have demonstrated high levels of transient heterologous gene expression both in vitro and in vivo and, therefore, possess attractive features for vaccine development. The most commonly used delivery vectors are based on three singl
Externí odkaz:
https://doaj.org/article/54af5c9b4ac04047bf2d205b731b9c46
Autor:
Han Si, Paola Scaffidi, Anand Merchant, Maggie Cam, Eric Stahlberg, Tom Misteli, Patricia Fernandez
Publikováno v:
Genomics Data, Vol 3, Iss C, Pp 33-35 (2015)
Hutchinson–Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have recently reported that HGPS cells are refractory to experimental oncogenic transformation and we ide
Externí odkaz:
https://doaj.org/article/9ec7ffad5c25415cb9a09e60fa0afdf1
Autor:
Eng Wee Chua, Nor Fadilah Rajab, Muhammad Asyaari Zakaria, Gayathri Thevi Selvarajah, Siti Fathiah Masre
Publikováno v:
Cancer Investigation. 38:445-462
Tissues become more rigid during tumorigenesis and have been identified as a driving factor for tumor growth. Here, we highlight the concept of tissue rigidity, contributing factors that increase tissue rigidity, and mechanisms that promote tumor gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d24dc74b7a4b28680eae83418fcef38
https://doi.org/10.1080/07357907.2020.1802474
https://doi.org/10.1080/07357907.2020.1802474
Autor:
Laura Corrales-Diaz Pomatto, Michel Bernier, Sophia R. Levan, Evi M. Mercken, Jonathan Kato, Kevin J. Pearson, Rafael de Cabo, Theresa Dill, Bethany A. Carboneau
Publikováno v:
Free Radic Biol Med
Caloric restriction (CR) is the leading non-pharmaceutical dietary intervention to improve health- and lifespan in most model organisms. A wide array of cellular pathways is induced in response to CR and CR-mimetics, including the transcriptional act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931e943f661f7b7882beff639cadb838
https://europepmc.org/articles/PMC7382945/
https://europepmc.org/articles/PMC7382945/
Publikováno v:
Cancer Immunology ISBN: 9783030308445
High serum concentrations of IL-1β and IL-18 are correlated to malignancies with low-rate survival from time of diagnosis. The multimeric complex of the inflammasome is responsible for IL-1β/IL-18 synthesis/release. A number of endogenous (damage-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f3f5a020dff4dd9438c6f0d9926b08
https://doi.org/10.1007/978-3-030-30845-2_15
https://doi.org/10.1007/978-3-030-30845-2_15
Autor:
André Uchimura Bastos, Carlos Fm Menck, Davi Jardim, Clarissa Rr Rocha, Marcela Teatin Latancia, Natália Cestari Moreno
Publikováno v:
Cancer Research. 80:4089-4089
Translesion DNA polymerases are capable of replicating damaged DNA, without removing the lesions, performing translesion synthesis (TLS), a mechanism of DNA damage tolerance. Tumor cells use this mechanism in order to survive lesions caused by chemot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c55dbe74a93feee4885916c54a03c8
https://doi.org/10.1158/1538-7445.am2020-4089
https://doi.org/10.1158/1538-7445.am2020-4089
Autor:
Dorothy E. Vatner, Wen Y. Chen, Arnold B. Rabson, Lydia Puricelli, Krista M. D. La Perle, María José Carlini, Erdene Baljinnyam, Thomas E. Wagner, Sanford P. Bishop, Stephen F. Vatner, Mariana S. De Lorenzo
Publikováno v:
Aging Cell
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Disruption of adenylyl cyclase type 5 (AC5) knockout (KO) is a novel model for longevity. Because malignancy is a major cause of death and reduced lifespan in mice, the goal of this investigation was to examine the role of AC5KO in protecting against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34532406a55dc61e51af75cdac4a1c1a
http://europepmc.org/articles/PMC3980454
http://europepmc.org/articles/PMC3980454
Autor:
Bhupinder Singh, Atul Jain, Rajneet Kaur Khurana, Teenu Sharma, Prashant Kesharwani, Ashay Jain
Publikováno v:
Drug discovery today. 23(4)
Several randomized clinical trials have divulged that administration of antioxidants during chemotherapy decreases the effectiveness of treatment. Hence, the characteristic feature of this article is extensive assessment of putative benefits and pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42093f3a05dd590c180d5d4a8e4085b9
https://pubmed.ncbi.nlm.nih.gov/29317341
https://pubmed.ncbi.nlm.nih.gov/29317341
Autor:
Eric Stahlberg, Anand S. Merchant, Paola Scaffidi, Maggie Cam, Han Si, Patricia Fernandez, Tom Misteli
Publikováno v:
Genomics Data, Vol 3, Iss C, Pp 33-35 (2015)
Genomics Data
Genomics Data
Hutchinson–Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have recently reported that HGPS cells are refractory to experimental oncogenic transformation and we ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d23d6d01ae339e181c3cae5c35dd9b
http://www.sciencedirect.com/science/article/pii/S2213596014001184
http://www.sciencedirect.com/science/article/pii/S2213596014001184