Zobrazeno 1 - 10
of 5 994
pro vyhledávání: '"Tumor promotion"'
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34961- (2024)
Background: The functions of the ELOVLs are mainly involved in the elongation of saturated and polyunsaturated fatty acids, thus influencing the metabolism of fatty acids. Abnormal lipid metabolism may result in NAFLD and NASH, which may lead to cirr
Externí odkaz:
https://doaj.org/article/e985b5aea5b045e7ba788c8d0d8fd563
Publikováno v:
Zhongguo linchuang yanjiu, Vol 37, Iss 1, Pp 6-11 (2024)
Mast cells are a type of innate immune cells, and have long been considered to be related to the pathogenesis of allergic and autoimmune diseases. However, in recent years, a number of studies have found that mast cells play an indispensable role in
Externí odkaz:
https://doaj.org/article/0835272fb9a84a5f81d1ad3e1d5afd59
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Functional role of Rho GDP-dissociation inhibitor beta (RhoGDIβ) in tumor biology appears to be contradictory across various studies. Thus, the exploration of the molecular mechanisms underlying the differential functions of this
Externí odkaz:
https://doaj.org/article/fafc6730e67545929a1b9829631282b8
Autor:
Zhiying Shao, Wendong Yang, Xiannan Meng, Minle Li, Pingfu Hou, Zhongwei Li, Sufang Chu, Junnian Zheng, Jin Bai
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11177-11190 (2023)
Abstract Background Yin Yang‐1 (YY1) is identified as a transcription factor with multiple functions. However, the role of YY1 in tumorigenesis remains controversial and its regulatory effects may depend upon not only cancer types, but also its int
Externí odkaz:
https://doaj.org/article/48fc82e5a16f4b6a8867f4845fb2f7e2
Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to the emergence of traditional drug resistance in tumor treatment, the anti-cancer therapies are facing multiple challenges. Immunotherapy, as a new and universal treatment, has been gradually concerned. The macrophages, as an important part of
Externí odkaz:
https://doaj.org/article/46eec2a8ac6d447b8330ac66ff6f18b5
Autor:
Eric Solary, Lucie Laplane
Publikováno v:
Evolutionary Applications, Vol 13, Iss 7, Pp 1756-1770 (2020)
Abstract Somatic mutations in oncogene and tumor suppressor genes accumulate in healthy tissues throughout life and delineate clones with limited expansion. Lifestyle‐related toxic insults increase the size and number of these clones that participa
Externí odkaz:
https://doaj.org/article/96ec2e7950ab4755bee1fa1c35f181c6
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103375- (2021)
Cholangiocarcinoma (CCA) is an aggressive and multifactorial malignancy of the biliary tract. The carcinogenesis of CCA is associated with genomic and epigenetic abnormalities, as well as environmental effects. However, early clinical diagnosis and r
Externí odkaz:
https://doaj.org/article/ab102acf7ed64f9e9927934a673dea45
Autor:
Veronica Angela Maria Vitto, Silvia Bianchin, Alicia Ann Zolondick, Giulia Pellielo, Alessandro Rimessi, Diego Chianese, Haining Yang, Michele Carbone, Paolo Pinton, Carlotta Giorgi, Simone Patergnani
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1596 (2022)
Autophagy is an evolutionarily conserved and tightly regulated process that plays an important role in maintaining cellular homeostasis. It involves regulation of various genes that function to degrade unnecessary or dysfunctional cellular components
Externí odkaz:
https://doaj.org/article/5758ca11a4c6496c91868f4443b85b18
Akademický článek
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