Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Tumor necrosis factor-alpha inhibitor"'
Autor:
Mihoko Yabuuchi, Kazuhito Yokoyama
Publikováno v:
Immunological Medicine, Vol 47, Iss 3, Pp 130-141 (2024)
Although Janus kinase inhibitor (JAKi) therapy is used for patients with autoimmune diseases (AD), one safety concern, interstitial lung disease (ILD), is life-threatening. We evaluated actual usage of JAKi and safety upon JAKi treatment, in an epide
Externí odkaz:
https://doaj.org/article/b7a6397a7fe5457b9d496f0d4f477eb7
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Background Ustekinumab is an interleukin (IL)-12/IL-23 inhibitor for the treatment of moderate-to-severe psoriasis.Objective This real-world study compared ustekinumab and tumor necrosis factor-alpha inhibitors (TNFis) in Chinese moderate-to-severe p
Externí odkaz:
https://doaj.org/article/12de7222177a40edac4b09b5b32c9569
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Background: This paper aims to analyse the active components of Semen cuscutae (SC) by network pharmacology and screen the most stable compounds with tumour necrosis factor-alpha (TNF-α) by molecular docking to explore the mechanisms of SC treatment
Externí odkaz:
https://doaj.org/article/aee0bacf0c63460ebc8043bf019163e7
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 32, Iss , Pp 101908- (2023)
Purpose: To report the clinical and histopathologic features of necrobiosis lipoidica and associated retinal vasculitis and describe successful treatment of both skin and eye manifestations with adalimumab, a tumor necrosis factor (TNF)-alpha inhibit
Externí odkaz:
https://doaj.org/article/c344729fead54d6990dcb66ec843bd4e
Autor:
Tsutomu Takeuchi, Yukihiro Chino, Masafumi Kawanishi, Megumi Nakanishi, Hirotaka Watase, Yoko Mano, Yuri Sato, Saeko Uchida, Yoshiya Tanaka
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Introduction Ozoralizumab (OZR), a tumor necrosis factor alpha (TNFα) inhibitor, is a NANOBODY® compound that binds to TNFα and human serum albumin. The main objective of this study was to analyze the pharmacokinetics (PK) of the drug and
Externí odkaz:
https://doaj.org/article/fbe57d38f1144fd98a623e2911891b98
Autor:
Ashmeetha Manilall, Lebogang Mokotedi, Sulè Gunter, Regina Le Roux, Serena Fourie, Colleen A. Flanagan, Aletta M. E. Millen
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Titin phosphorylation contributes to left ventricular (LV) diastolic dysfunction. The independent effects of inflammation on the molecular pathways that regulate titin phosphorylation are unclear. Methods We investigated the effec
Externí odkaz:
https://doaj.org/article/73f4db01916a4900874dfedfb2989ff8
Autor:
Robert Lersch, Guido Mandilaras, Meike Schrader, Felicitas Anselmino, Nikolaus A. Haas, André Jakob
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
A small group of patients with Kawasaki disease (KD) demonstrates resistance to standard therapy, putting them at high risk for an unfavorable prognosis, especially regarding coronary artery aneurysms. Although adding corticosteroids to first-line i.
Externí odkaz:
https://doaj.org/article/4b50be6726be46bcae6de39419c57cfa
Autor:
Jongwook Yu, Hye Kyung Hyun, Jihye Park, Eun Ae Kang, Soo Jung Park, Jae Jun Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Publikováno v:
Gut and Liver, Vol 16, Iss 3, Pp 414-422 (2022)
Background/Aims: Many patients with Crohn’s disease (CD) undergo intestinal resection during the disease course. Despite surgery, postoperative recurrence (POR) commonly occurs. Although postoperative use of tumor necrosis factor α (TNF-α) inhibi
Externí odkaz:
https://doaj.org/article/34b5d74e54924a6c91cd89e9901263b9
Publikováno v:
European Journal of Breast Health, Vol 18, Iss 1, Pp 94-101 (2022)
Idiopathic granulomatous mastitis (IGM) is a rare, benign, inflammatory breast disease that primarily affects parous women within a period of five years post-partum. Cystic neutrophilic granulomatous mastitis (CNGM) is clinically identical to IGM, bu
Externí odkaz:
https://doaj.org/article/f94918c37b144299ab5166a1550bb098
Autor:
Rachel A. Brown, Fatima Barbar-Smiley, Cagri Yildirim-Toruner, Monica I. Ardura, Stacy P. Ardoin, Shoghik Akoghlanian
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Background Children with rheumatic diseases (cRD) receiving immunosuppressive medications (IM) are at a higher risk for acquiring potentially lethal pathogens, including Histoplasma capsulatum (histoplasmosis), a fungal infection that can le
Externí odkaz:
https://doaj.org/article/8732228570b140d7bfdf9a5ae86de86f