Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Tumor microenviroment"'
Autor:
Hannah Nelson, Sherman Qu, Jeffrey L. Franklin, Qi Liu, Heather H. Pua, Kasey C. Vickers, Alissa M. Weaver, Robert J. Coffey, James G. Patton
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 17-31 (2024)
Extracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological s
Externí odkaz:
https://doaj.org/article/0149ce03e8b64eb8b051c0b241d31077
Autor:
Zhen Zhen Wang, Xiao Ling Wen, Na Wang, Xu Hua Li, Yu Guo, Xu Zhu, Shu Heng Fu, Fei Fan Xiong, Jin Li, Limei Wang, Xiao Ling Gao, Hong Jiu Wang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background IFN-λ has been shown to have a dual function in cancer, with its tumor-suppressive roles being well-established. However, the potential existence of a negative ‘‘tumor-promoting’’ effect of endogenous IFN-λ is still not
Externí odkaz:
https://doaj.org/article/11ea0a4723dd49eaa947fca90f82b664
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Malignant melanoma (MM) is the most metastatic and aggressive form of skin cancer, and carries a high risk of death. Immune-checkpoint inhibitor therapy and molecular-targeted therapy can prolong the survival of patients with advanced MM significantl
Externí odkaz:
https://doaj.org/article/eda193b1d01849219a9cc068e0060223
Autor:
Ana Montero-Calle, Itziar Aranguren-Abeigon, María Garranzo-Asensio, Carmen Poves, María Jesús Fernández-Aceñero, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, Javier Rodriguez-Cobos, Guillermo Solís-Fernández, Eloy Povedano, Maria Gamella, Rebeca Magnolia Torrente-Rodríguez, Miren Alonso-Navarro, Vivian de los Ríos, J. Ignacio Casal, Gemma Domínguez, Ana Guzman-Aranguez, Alberto Peláez-García, José Manuel Pingarrón, Susana Campuzano, Rodrigo Barderas
Publikováno v:
Engineering, Vol 7, Iss 10, Pp 1393-1412 (2021)
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. The five-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stages but lower than 10% w
Externí odkaz:
https://doaj.org/article/37d8fc52650e413c80d384b5a7c4075f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundColorectal adenocarcinoma (COAD) is one of the most common malignancies and angiogenesis is vital to the development of cancer. Here, we explored the roles of angiogenesis-related genes (ARGs) that affect the prognosis of COAD and construct
Externí odkaz:
https://doaj.org/article/62b5dffc63874097964cd1def5fb8913
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing. First, we presented a multi-omics scale
Externí odkaz:
https://doaj.org/article/6beab90f051343f08315aaab9188e9c5
Autor:
Isabella Giacomini, Monica Montopoli
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/07c6aab840454fa59050e88826820fc1
Autor:
Maria Rosaria Ruocco, Annalisa Lamberti, María José Serrano, Giuseppe Fiume, Alessandro Arcucci
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/17d60300e2294dd49b471730261100c6
Autor:
Anna Pasetto, Yong-Chen Lu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cells have been known to be the driving force for immune response and cancer immunotherapy. Recent advances on single-cell sequencing techniques have empowered scientists to discover new biology at the single-cell level. Here, we review the single-
Externí odkaz:
https://doaj.org/article/6c5cf338d89246f1bdc01a44cd6a7e59
Publikováno v:
Frontiers in Oral Health, Vol 2 (2021)
Background: The tumor microenvironment (TME) of oral squamous cell carcinoma (OSCC) is associated with immune suppression, one of the pathways being the programmed death receptor 1 (PD-1) and its ligands (PD-L1/PD-L2). Checkpoint inhibitors of PD-1/P
Externí odkaz:
https://doaj.org/article/6ba9ee45480c46a6aa46ba57a2dd149d