Zobrazeno 1 - 10
of 695
pro vyhledávání: '"Tumor associated macrophages (TAMs)"'
Autor:
Zhe Zhang, Yao Xiao, Siyi Zhao, Jun Liu, Jie Zeng, Feng Xiao, Bin Liao, Xuesong Shan, Hong Zhu, Hua Guo
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Family with sequence similarity 109, member B (FAM109B) is involved in endocytic transport and affects genetic variation in brain methylation. It is one of the important genes related to immune cell-associated diseases. In the tum
Externí odkaz:
https://doaj.org/article/2b6a81e3ffa04a5892e57ead678f5717
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Tumor-associated macrophages (TAMs) are pivotal in cancer progression, influencing tumor growth, angiogenesis, and immune evasion. This review explores the spatial and temporal heterogeneity of TAMs within the tumor microenvironment (TME), h
Externí odkaz:
https://doaj.org/article/d1f98eb6fcff4d46bd52d7696aad735d
Autor:
Fan Guo, Weina Kong, Dewei Li, Gang Zhao, Miyessar Anwar, Feifei Xia, Yuanming Zhang, Cailing Ma, Xiumin Ma
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background and purpose PD-1/PD-L1 inhibitors have become a promising therapy. However, the response rate is lower than 30% in patients with cervical cancer (CC), which is related to immunosuppressive components in tumor microenvironment (TME
Externí odkaz:
https://doaj.org/article/29645eaa7b054ce9acb617740adc04c8
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
This review provides an in-depth summary of the development of anti-cancer drugs for tumor-associated macrophages (TAMs), with a particular focus on the development and tissue specialization of macrophages, and factors influencing the polarization of
Externí odkaz:
https://doaj.org/article/f5345885e5834cb8a95d4494a4c44782
Autor:
Ana Sami, Afsheen Raza
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Breast cancer has the highest global incidence among all cancers, affecting more than 2 million individuals annually. Despite the availability of new drugs and novel treatment combinations, it is postulated that the incidence and mortality of breast
Externí odkaz:
https://doaj.org/article/c13555746f324d95bce5cc5e85384fc9
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract The tumor microenvironment (TME) constitutes a complex microenvironment comprising a diverse array of immune cells and stromal components. Within this intricate context, tumor-associated macrophages (TAMs) exhibit notable spatial heterogenei
Externí odkaz:
https://doaj.org/article/46421d96d3254d59b417d6d16472da6f
Autor:
Jacek Kuźnicki, Natalia Janicka, Barbara Białynicka-Birula, Wojciech Kuźnicki, Hanna Chorążyczewska, Iwona Deszcz, Julita Kulbacka
Publikováno v:
Cells, Vol 13, Iss 23, p 1948 (2024)
Numerous studies have demonstrated the significant influence of immune cells on cancer development and treatment. This study specifically examines tumor-associated macrophages (TAMs), detailing their characteristics and roles in tumorigenesis and ana
Externí odkaz:
https://doaj.org/article/05a46253f07948ca9b8733bc0b08e73a
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Hepatocellular carcinoma (HCC) is one of the cancers that seriously threaten human health. Immunotherapy serves as the mainstay of treatment for HCC patients by targeting the programmed cell death protein 1/programmed cell death 1 ligand 1 (PD-1/PD-L
Externí odkaz:
https://doaj.org/article/85f0bdd94d9a4b56a1ca3acfc2e4c3a3
Autor:
Kana Shibata, Nobutaka Koibuchi, Fumihiro Sanada, Naruto Katsuragi, Yuko Kanemoto, Yasuo Tsunetoshi, Shoji Ikebe, Koichi Yamamoto, Ryuichi Morishita, Kenzo Shimazu, Yoshiaki Taniyama
Publikováno v:
Cells, Vol 13, Iss 17, p 1410 (2024)
Background: Periostin (POSTN) is a type of matrix protein that functions by binding to other matrix proteins, cell surface receptors, or other molecules, such as cytokines and proteases. POSTN has four major splicing variants (PN1–4), which are pri
Externí odkaz:
https://doaj.org/article/7f3f92684ed748aba17d0ba96d6907e0
Autor:
Camila Sales Nascimento, Naiara Clemente Tavares, Izabella Cristina Andrade Batista, Mônica Maria Magalhães Caetano, Eneida Santos de Oliveira, Stella Garcia Colombarolli, Anna Carolina Pinheiro Lage, Rodrigo Corrêa-Oliveira, Érica Alessandra Rocha Alves, Celso Pinto de Melo, Carlos Eduardo Calzavara-Silva
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Background Breast cancer is the neoplastic disease with the highest incidence and mortality in the female population worldwide. Treatment remains challenging due to various factors. Therefore, it is of great importance to develop new therape
Externí odkaz:
https://doaj.org/article/09ea05dbb5bc469cac2d97cbe9ddaf1e