Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Tumor Suppressor Protein p53/*biosynthesis"'
1
Differential expression of anti-apoptotic protein Bcl-2 in keratinizing versus non-keratinizing squamous cell carcinoma of the anus
Autor: Pascal Gervaz, Abdelkarim S. Allal, Marie-Anne Brundler
Publikováno v: International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery, Vol. 20, No 2 (2005) pp. 161-4
Background: Histologically, tumors of the anal region are either keratinizing (K) or non-keratinizing (NK) squamous cell carcinomas (SCCA). We hypothesized that these two variants might represent, not only morphologically, but also biologically, diss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4275aa19c67ac196f5047a278657e7
https://doi.org/10.1007/s00384-004-0651-z
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2
初発の表在性低悪性度の膀胱癌においては, 増殖状態が再発危険因子である
Autor: Su, Jing-Shi, Arima, Kiminobu, Hasegawa, Mariko, Franco, Omar E., Yanagawa, Makoto, Sugimura, Yoshiki, Kawamura, Juichi
Publikováno v: 泌尿器科紀要. 49(11):649-658
再発危険因子検索のため, pTa33例とpTl46例の膀胱癌患者にKi-67, c-erbB-2, p53と多薬剤耐性蛋白(MRP)を免疫組織化学的に検討した.その結果, pTl, 広基性, 腫瘍径の大きな腫瘍(>3cm)の再発率は高か
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::666251f665570daccee6087c78337f67
http://hdl.handle.net/2433/115080
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3
p53 as a potential predictive factor of response to chemotherapy: feasibility of p53 assessment using a functional test in yeast from trucut biopsies in breast cancer patients
Autor: S Bongard, E Lurati, Richard Iggo, Hervé Bonnefoi, S Movarekhi, A Ducraux, M F Pelte
Publikováno v: British Journal of Cancer
British Journal of Cancer, vol. 86, no. 5, pp. 750-755
Assessment of the predictive value of p53 requires the testing of large numbers of samples from patients enrolled in prospective phase III clinical trials. The goal of this study was to determine whether p53 status can be determined by p53 yeast func
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c407ba6c5816d1f1826eef13a724291
http://europepmc.org/articles/PMC2375302
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4
Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed-Sternberg cells
Autor: Vassiliki Galani, Sevasti Kamina, Panagiotis Kanavaros, Kalliopi Stefanaki, Constantina Grepi, Niki J. Agnantis, Elena Tsanou, Maria Bai, Dimitra Rontogianni
Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 17(11)
There is accumulating evidence that Hodgkin's and Reed-Sternberg cells of classical Hodgkin's lymphomas (cHL) display multiple and concurrent alterations in different pathways and checkpoints of the cell cycle. However, the expression of cyclin D2 an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cac71d5651f8634102dd7c5d09f1999
https://pubmed.ncbi.nlm.nih.gov/15354186
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5
Expression of cyclin D3 and cyclin E and identification of distinct clusters of proliferation and apoptosis in diffuse large B-cell lymphomas
Autor: Bai, M., Tsanou, E., Agnantis, N. J., Aristeidis Chaidos, Dimou, D., Skyrlas, A., Dimou, S., Vlychou, M., Galani, V., Kanavaros, P.
Publikováno v: Scopus-Elsevier
DIGITUM. Depósito Digital Institucional de la Universidad de Murcia
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In the present study 79 cases of de novo Diffuse Large B-cell Lymphomas (DLBCL) were studied in order: a) to analyse the expression of cyclin D3, cyclin E and cyclin D1 in relation to other proliferative features (expression of Ki67, cyclin A and cyc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::973c4315e7113ac394c80f1f9a25addc
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6
Expression of cathepsin D in urothelial carcinoma of the urinary bladder: an immunohistochemical study including correlations with extracellular matrix components, CD44, p53, Rb, c-erbB-2 and the proliferation indices
Autor: Ioachim, E., Antonia Charchanti, Stavropoulos, N., Athanassiou, E., Bafa, M., Agnantis, N. J.
Publikováno v: Scopus-Elsevier
The immunohistochemical Cathepsin D (CD) expression of tumor and stromal cells was investigated in a series of 77 urothelial carcinomas of the urinary bladder with the intention to evaluate its prognostic significance and its contribution to the meta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90e83ee066130e026a1375955691d0fb
http://olympias.lib.uoi.gr/jspui/handle/123456789/21707
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7
Low expression of p27 protein combined with altered p53 and Rb/p16 expression status is associated with increased expression of cyclin A and cyclin B1 in diffuse large B-cell lymphomas
Autor: Bai, M. C., Vlachonikolis, J., Agnantis, Niki J., Tsanou, E., Dimou, S., Nikolaides, C., Stefanaki, S. V., Pavlidis, Nicholas, Kanavaros, P.
Publikováno v: Modern Pathology
The expression of the cyclin-dependent kinase inhibitor (CDKI) p27 protein was investigated in relation to (1) the expression of the cell cycle regulators p53, Rb and p16 and (2) the proliferation profile as determined by the expression of Ki67, cycl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a45cd63e3f9847587df6ca3cb8d2860
http://olympias.lib.uoi.gr/jspui/handle/123456789/20306
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8
Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size
Autor: Jean Marie Blanchard, Jacques Piette, Nicole Basset-Seguin, Jean Eudes Dazard, Alberto Gandarillas
Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2000, 19 (33), pp.3693--705
Oncogene, Nature Publishing Group, 2000, 19 (33), pp.3693--705. ⟨10.1038/sj.onc.1203695⟩
p53 transcription factor is mutated in most skin cell carcinomas and in more than 50% of all human malignancies. One of its transcriptional targets is MDM2, which in turn down-regulates p53. The role of the p53/MDM2 regulatory loop upon genotoxic str
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0453596296df0fbbcf7c9a57dbccb9c8
https://pubmed.ncbi.nlm.nih.gov/10949923
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9
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis
Autor: Gomez-Manzano, C., Fueyo, J., Kyritsis, A. P., McDonnell, T. J., Steck, P. A., Levin, V. A., Yung, W. K.
BACKGROUND: Alterations of the p53 (also called TP53) gene are one of the most common abnormalities in gliomas. We have previously reported that restoration of wild-type p53 protein function in glioma cells results in programmed cell death (apoptosis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::bbbab869fa3874aa8af936f2b8fb4ec7
http://olympias.lib.uoi.gr/jspui/handle/123456789/23171
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10
Mycosis fungoides: expression of C-myc p62 p53, bcl-2 and PCNA proteins and absence of association with Epstein-Barr virus
Autor: J. Katsantonis, P. Kanavaros, G. Delidis, Androniki D. Tosca, D. Ioannidou, M. Tzardi, Datseris G
The expression of C-myc p62, bcl-2, p53, PCNA and EBV-encoded LMP-1 proteins was studied by immunohistochemistry on paraffin-embedded skin specimens from 14 patients with early stage (premycotic erythema and second stage plaques) mycosis fungoides (M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e1fdd0a695fe67de2a3d70cce365a0
http://olympias.lib.uoi.gr/jspui/handle/123456789/19838
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